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Báo cáo Y học: A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H37Rv and the secreted chorismate mutase (y2828) from Yersinia pestis pptx

Báo cáo Y học: A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H37Rv and the secreted chorismate mutase (y2828) from Yersinia pestis pptx

Báo cáo Y học: A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H37Rv and the secreted chorismate mutase (y2828) from Yersinia pestis pptx

... of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H37Rv and the secreted chorismate mutase (y2 828) from Yersinia pestis Sook-Kyung Kim*, Sathyavelu K. Reddy, Bryant ... dehydrogenase and prephenate dehydratase catalyze the biosynthesis of tyrosine and phenylalanine, respectively. As this bio-synthetic pathway is absent in mammals but is essen-tial for the survival of ... *YpCM, secreted chorismate mutase from Yersinia pestis; CM, chorismate mutase; EcCM, chorismate mutase domain of chorismate mutase prephenate dehydratase from Escherichia coli; IPTG,isopropyl-thio-b-D-galactoside;...
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Báo cáo Y học: Azidothymidine causes functional and structural destruction of mitochondria, glutathione deficiency and HIV-1 promoter sensitization pptx

Báo cáo Y học: Azidothymidine causes functional and structural destruction of mitochondria, glutathione deficiency and HIV-1 promoter sensitization pptx

... Saitama, JapanMitochondrial functional and structural impairment and generation of oxidative stress have been implicated in aging,various diseases and chemotherapies. This study analyzedazidothymidine ... Kurata11Department of Biochemical Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan;2Ikawa Laboratory, RIKEN, The Institute of Physical and Chemical Research, Wako, ... Reduction of CAT activity by NAC-incorporation after15-day incubation with AZT or 25-day incu-bation with H2O2. Results of the CAT assayare shown in chromatograms (a) and relativeenzyme activities...
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Báo cáo khoa học: Site-directed mutagenesis and footprinting analysis of the interaction of the sunflower KNOX protein HAKN1 with DNA ppt

Báo cáo khoa học: Site-directed mutagenesis and footprinting analysis of the interaction of the sunflower KNOX protein HAKN1 with DNA ppt

... 5¢-GCGGAATTCAAAAAGAGAAAGAAAGGG-3¢ and MALC:5¢-GGCCTGCAGCTAGAGAAGTGAAACATC-3¢ withHAKN1 cDNA [28] as the template.An I50S mutant was constructed using complementaryoligonucleotides I50SF and I50SR ... byfilling-in the 3¢-ends using the Klenow fragment of DNApolymerase) generated by hybridization of the complement-ary oligonucleotides 5¢-AATTCAGATCTTGTGACAGAAGAG-3¢ and 5¢-GGATCCTCTTCTGTCACAAGATCTG-3¢, ... hydro-xyl radical attack, free (F) and bound (B) DNA were separated and analysed. The left and right panels in (A) and (B) represent the top and bottom strands of the binding site, respectively. A...
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Báo cáo khoa học: Phosphatidylserine induces functional and structural alterations of the membrane-associated pleckstrin homology domain of phospholipase C-d1 docx

Báo cáo khoa học: Phosphatidylserine induces functional and structural alterations of the membrane-associated pleckstrin homology domain of phospholipase C-d1 docx

... domain of phospholipase C-d1Naoko Uekama, Takio Sugita, Masashi Okada, Hitoshi Yagisawa and Satoru TuziGraduate School of Life Science, University of Hyogo, Harima Science Garden City, Kamigori, ... X-ray diffraction. Asshown with dotted lines, the chemical shifts of the sig-nals of Ala116 and Ala118 are not affected by addition of PS, indicating that conformations of Ala116 and Ala118 ... within the C-terminal a3 -helix of the PHdomain are unchanged. These signals are indifferent to the presence of the membranes, probably because the positions of Ala116 and Ala118 are located far from the...
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Báo cáo y học:

Báo cáo y học: "Lifetime health effects and medical costs of integrated stroke services - a non-randomized controlled cluster-trial based life table approach"

... dis-ability after stroke, and the four probabilities of death -affect patients’ courses in the same way as they did in the original life-table model [5]. The annual probability of a vascular ... cardiovascular events separately. Finally,patients can leave the model because of any other, (iv)non-related cause of death. All death, incidence and recurrences rates are stroke severity specific and ... early institutionalized rehabilitation by a multidisciplinary team [33]. However, length of stay instroke units may vary within Europe and this maychange the financial, short-term, impact of...
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Báo cáo y học:

Báo cáo y học: "A Comparative Effectiveness Study of Bone Density Changes in Women Over 40 Following Three Bone Health Plans Containing Variations of the Same Novel Plant-sourced Calcium"

... meta -analysis [5] of randomized trials in-volving 63,897 subjects 50 years of age and older, most of whom were healthy postmenopausal women with an average age of 67.8 years. The meta -analysis ... benefit of adding the physi-cal activity and health literacy components, the data also support the efficacy of plant-source calcium as a stand-alone product. Authors’ Contributions Kaats GR was ... was the principal investigator; he se-cured and audited all study data, conducted all of the statistical analyses, and contributed significantly to the preparation and submission of the manuscript....
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Báo cáo y học:

Báo cáo y học: "A comparative analysis of antibody repertoire against Staphylococcus aureus antigens in Patients with Deep-Seated versus Superficial staphylococcal Infections"

... quantitative measurement of IgG antibodies to peptidoglycan and teichoic acid in sera from patients and healthy controls was checked by ELISA. The sera obtained from both patients and healthy controls ... we used the commercially available PG and TA 3.6 Correlation coefficients We analyzed the correlation of levels of anti- peptidoglycan and teichoic acid antibodies in sera from patients with ... group and healthy control group. These two unique bands are likely to be of diagnostic value. The diagnostic efficacy of antibody detection tests was not the primary objective of this study and...
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Báo cáo y học:

Báo cáo y học: "Foramen Magnum Arachnoid Cyst Induces Compression of the Spinal Cord and Syringomyelia: Case Report and Literature Review"

... The commonest type of arachnoid cyst that causes compression of the spinal cord and develop-ment of syringomyelia is the Chiari malformation type I [1]. Other types of arachnoid cysts can ... 2011.05.27 Abstract It is very rare that a foramen magnum arachnoid cyst induces compression of the spinal cord and syringomyelia, and currently there are few treatment experiences available. Here ... the su-pratentorial ventricular system was normal (Figure 1). Based on history and physical and MRI examinations, we diagnosed the lesion as a foramen magnum arachnoid cyst with syringomyelia....
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Báo cáo y học:

Báo cáo y học: "Multivariate explanatory model for sporadic carcinoma of the colon in Dukes’ stages I and IIa"

... phosphatase (AP), and the CA 19.9 marker as predic-tors [20]. Sample size was taken into account [21]. A first analysis was made on the “raw” data package. The selection of variables was always ... format for its later sta-tistical analysis, and the quality controls were also made at this stage. Statistical analysis An initial study was made on the set of records to obtain centralization ... moment of the construction of the data package. The funda-mental cause was the lack of fulfilment of the inclu-sion criteria. The assembly of the previous data package with a total of 93 records...
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