... Saitama, JapanMitochondrial functional and structural impairment and generation of oxidative stress have been implicated in aging,various diseases and chemotherapies. This study analyzedazidothymidine ... Kurata11Department of Biochemical Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan;2Ikawa Laboratory, RIKEN, The Institute of Physical and Chemical Research, Wako, ... Reduction of CAT activity by NAC-incorporation after15-day incubation with AZT or 25-day incu-bation with H2O2. Results of the CAT assayare shown in chromatograms (a) and relativeenzyme activities...