Báo cáo khoa học: Cellular retinol-binding protein type II (CRBPII) in adult zebraﬁsh (Danio rerio) cDNA sequence, tissue-speciﬁc expression and gene linkage analysis pptx

... acid binding protein; cellular retinol binding protein; tissue-specific expression; retinolmetabolism. Cellular retinol-binding proteins (CRBPs) are members ofthe intracellular lipid-binding protein ... Cellular retinol-binding protein type II (CRBPII) in adult zebrafish (Danio rerio) cDNA sequence, tissue-specific expression and gene linkage analysis Marianne C. Cameron1, ... zebrafish cDNA clone that codes for a cellular retinol-binding protein type II (CRBPII). Radiation hybrid mapping revealed thatthe zebrafish and human CRBPII genes are located in syntenic groups. In...

Tài liệu Báo cáo khoa học: Molecular determinants of ligand speciﬁcity in family 11 carbohydrate binding modules – an NMR, X-ray crystallography and computational chemistry approach doc

... for screening and identifying ligand binding to protein receptors. Angewandte Chemie-International Edi-tion 42, 864–890.16 Mayer M & Meyer B (1999) Characterization of ligandbinding by saturation ... could indicate that the corre-sponding hydroxyl groups are involved in protein binding.The results for the linebroadening measurements ofprotons H1a in the alpha and beta conﬁgurations,aHa1 and ... protein modules havebeen grouped into three subfamilies: ‘surface-binding’CBMs (type A), ‘glycan-chain-binding’ CBMs (type B), and ‘small sugar-binding’ CBMs (type C) [5].The focus of the present...

Báo cáo khoa học: The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco⁄endoplasmic reticulum calcium stores ppt

... class III phosphatidylinositol 3-kinase-interacting protein [11], plays a role in promotingautophagy [12]. Beclin 1 contains a Bcl-2-bindingdomain which may serve as a point of cross-talk betweenthe ... were incubated for 20 min in 2 lm Fluo-2 ⁄ AM at37 °C in MKH buffer. Then the dye-containing solutionwas replaced with dye-free MKH buffer containing 0.1 mmnorepinephrine and cells were incubated ... H+-ATPase inhibitor) to inhibitautophagosome–lysosome fusion [24], and E64d (5 lgÆmL)1,inhibitor of cysteine proteases, including cathepsin B), and PepA (5 lgÆmL)1, cathepsin D inhibitor) to inhibit...

Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/– pdf

... able t o bind lipoproteins containing apoB and apoE;(b) LSR displays high afﬁnity for T RL; (c) LSR b inding isinhibited by lactoferrin, receptor associated prote in ( RAP), and apoCIII, all ... band.Ó FEBS 2004 LSR gene and protein expression (Eur. J. Biochem. 271) 3107amount in adrenal glands was only 4 % of that o f liver.A substantial expression was found in intestine and brain(respectively ... oldstein, J .L., Orth, K., Brown, M.S. & H erz, J.(1992) Low density lipoprotein receptor-related protein and gp330bind similar ligands, including plasminogen activator-inhibitorcomplexes and...

Báo cáo khoa học: Serine-arginine protein kinases: a small protein kinase family with a large cellular presence potx

... October2010)doi:10.1111/j.1742-4658.2010.07987.xSerine-arginine protein kinases (SPRKs) constitute a relatively novelsubfamily of serine-threonine kinases that specifically phosphorylate serineresidues residing in serine-arginine ⁄ arginine-serine ... Reg-ulation of binding of lamin B receptor to chromatin bySR protein kinase and cdc2 kinase in Xenopus eggextracts. J Biol Chem 279, 13265–13271.Serine-arginine protein kinases T. Giannakouros ... resistance to cis-platin [58,59]. These tissue-specific findings again pointout the intricate and fine-tuned cellular networks regu-lated by SRPK activity.Serine-arginine protein kinases T. Giannakouros...

Báo cáo khoa học: Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-a pdf

... throughoutthe brain, and is involved in the regulation of energybalance by stimulating increased food intake. Pep-tide YY (PYY) is produced by the gastrointestinaltract, and, via NPY receptor binding, ... Pure E (2009)Targeting ﬁbroblast activation protein inhibits tumorstromagenesis and growth in mice. J Clin Invest 119,3613–3625.Substrates of ﬁbroblast activation protein F. M. Keane et al.1330 ... granulocyte chemotactic protein- 2;CXCL9 ⁄ MIG, C-x-C motif chemokine 9 ⁄ monokine induced by interferon-c ; CXCL10 ⁄ IP10, C-x-C motif chemokine 10 ⁄ interferon-c-induced protein 10; CXCL11 ⁄ ITAC,...

Báo cáo khoa học: Cellular and molecular action of the mitogenic protein-deamidating toxin from Pasteurella multocida pptx

... protein serine ⁄ threonine protein kinase; MEK, MAPK serine ⁄ threonine protein kinase; MLCK, myosin light chain kinase(serine ⁄ threonine protein kinase); MLCPase, myosin light chain phosphatase; ... threonine protein kinase-1; PKA, cAMP-dependent protein ser-ine ⁄ threonine kinase A; PKC, calcium-dependent serine ⁄ threonine protein kinase C; PKD, diacylglycerol-dependent serine ⁄ threonine protein kinase ... inhibiting factor; CREB, cAMP response element-binding protein; Erk, extracellularsignal-regulated serine ⁄ threonine protein kinase; JAK, Janus tyrosine protein kinase; MAPK, mitogen-activated protein...

Tài liệu Báo cáo khoa học: Transient RNA–protein interactions in RNA folding docx

... the properties of the three protein classes, with the main focus being on RNAchaperones and annealer proteins.Speciﬁcally binding proteinsA speciﬁc protein cofactor binds to its RNA targetthrough ... of lysines and arginines to oppose thenegatively charged sugar-phosphate RNA backbone isimportant, and they are found 1.5 and 1.4 times moreoften than in interfaces of protein- protein complexes[31]. ... theirresemblance to proteins with RNA-annealing activity.DEAD-box proteins should therefore be considered asmajor players in RNA folding and in the assembly and functioning of RNP machines, mostly...

Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx

... protein kinase; MAPKK, mitogen-activated protein kinase kinase; MBP, myelin basic protein; OXI1, oxidativesignal-inducible 1; PDK1, 3-phosphoinositide-dependent kinase 1; PTI1, Pto-interacting ... activation of the mitogen-activated protein kinases (MAP-Ks), MPK3 and MPK6, in response to oxidative stress. In addition, theserine ⁄ threonine protein kinase Pto-interacting 1-2 (PTI1-2) has beenpositioned ... subdomain VII of the catalytic domain and by the presence of an amino acid insertion of variablesize between subdomains VII and VIII [8,9]. Such asOXI, other AGC kinases of the AGC VIII subgrouphave...

Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

... enterobactin and coelichelin [6,7]. The C-terminal adenylation domainA4again is predicted to activate l-arginine, displaying60% identity to the characterized A-domain of MycC.Interestingly, A1 and ... (solvent A) and methanol ⁄ 0.05%formic acid (solvent B) at a ﬂow rate of 16 mLÆmin)1: lin-ear increase from 0% B to 50% within 50 min followed bya linear increase to 95% B in 5 min, holding B ... (solvent A) and methanol ⁄ 0.05% formic acid (solvent B) at a ﬂow rate of16 mLÆmin)1: linear increase from 0% B to 50% within50 min followed by a linear increase to 95% B in 5 min,holding B for...

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