Báo cáo Y học: A polymer with a backbone of 3-deoxy-D-glycero -D-galacto -non-2ulopyranosonic acid, a teichuronic acid, and a b-glucosylated ribitol teichoic acid in the cell wall of plant pathogenic Streptomyces sp VKM Ac-2124 pdf
Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... arginase and agmatinase. This aspect ispresently under investigation in our laboratory. In any case,despite the structural differences between agmatinase and arginase, agmatine and arginine ... the structural alignment. The alignment was then corrected byhand. Since the sequences of the two arginases and agmatinase greately differ in the N terminal region, the agmatinase and rat liver arginases ... Genetic Engineering and Biotechnology, Habana, CubaUpon mutation of Asp153 by asparagine, the catalyticactivity of agmatinase (agmatine ureohydrolase, EC3.5.3.11) from Escherichia coli was reduced...
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Báo cáo y học: "Users' guides to the medical literature: how to use an article about mortality in a humanitarian emergency"
... Relief-Web (a media and NGO repositorymaintained by the Office for the Coordination of Human-itarian Affairs), the Uppsala Conflict Database Program (a database that contains information on armed ... survey to determine the validity of the study and the applicability of the findings to theirsettings.Public health scenarioYou are a physician working for an international human-itarian medical ... Monitoring and Assessment of Relief and Transition (SMART) initiative and seek studies of high quality [3]. You will ask a support team in the capital,Kinshasa – your own electronic access is painfully...
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Báo cáo Y học: Novel fish hypothalamic neuropeptide Cloning of a cDNA encoding the precursor polypeptide and identification and localization of the mature peptide pptx
... carried out in a reactionmixture containing Taq polymerase [Ex Taq polymerase(Takara Shuzo, Kyoto, Japan) or gene Taq polymerase(NIPPON GENE, Tokyo, Japan)] and 0.2 mMdNTP on a thermal cycler ... lengths of poly (A) tail. The open reading frameregion began with a start codon at position 16 and terminated with a TAA stop codon at position 607. A single polyadenylation signal (AGTAAA) was found ... Hinuma, S., Shintani, Y. , Fukusumi, S., Iijima, N., Matsumoto, Y. , Hosoya, M., Fujii, R., Watanabe, T., Kikuchi, K., Terao, Y. ,Yano, T., Yamamoto, T., Kawamata, Y. , Habata, Y. , Asada,M., Kitada,...
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Báo cáo Y học: Expression pattern in the antennae of a newly isolated lepidopteran Gq protein a subunit cDNA potx
... cDNArevealed that there is a polyadenylation signal upstream of the poly (A) .Analysis of the primary structure of M. brassicaeGqa The putative protein product encoded by the cloned cDNAwas aligned ... liberating inositol 1,4,5-triphosphate (InsP3) and diacylglycerol. Although cAMP and InsP3cascadesappear to be active as two alternative pathways in vertebrate olfaction [7], mechanisms of olfactory ... wereseparated by SDS/PAGE and analysed by Western-blotusing a Gq/11 a antiserum (Fig. 1). Crude homogenates of male and female antennae contained an immunoreactiveband with an apparent molecular mass of...
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Báo cáo Y học: The mitochondrial-lysosomal axis theory of aging Accumulation of damaged mitochondria as a result of imperfect autophagocytosis ppt
... composition arebasically the same in aging and disease. In a lysosome, where different organelles and a variety of proteins and other macromolecules are degraded, the milieu is acidic and reducing, partly ... explanation for many of the features of aging. A number of early explanations of aging, such asOrgel’s error catastrophe theory and the somatic mutationtheory, were based on the idea that aging results ... lost withinlipofuscin-loaded lysosomes. Apparently, cells have a limitedcapacity to produce lysosomal enzymes, and as lipofuscin-containing lysosomes act as sinks for newly synthesizedenzymes,...
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Báo cáo Y học: Modeling the three-dimensional structure of H+-ATPase of Neurospora crassa Proposal for a proton pathway from the analysis of internal cavities pptx
... transports ions outs ide the cell in a nelectrogenic way using energy from M gATP hydrolysis and its catalytic cycle is characterized by the formation of a covalent enzyme-aspartyl phosphate intermediate[2,3,42,43]. The ... modelidentify a string of internal polar cavities, tracing a well-defined pathway connecting the phosphorylation site in the extracellular domain to the intracellular side of the mole-cule. Most of these ... domain is remarkablyconserved between the C a 2+-ATPase and the solublemembers of the haloacid dehalogenases whose catalyticactivity proceed essentially by the same mechanism. Indeed,catalytic...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... antiplateletagents, warfarin or niacin. Carbamazepine acts as aninducer of cytochrome 3A4 , which may increase the metabolism of some anticoagulant and cardiovascularmedications. Olanzapine may induce or ... with advanced cancer and pain. J Pain Symptom Manage 2002,23:526-532.83. Khojainova N, Santiago-Palma J, Kornick C, Breitbart W, GonzalesGR: Olanzapine in the management of cancer pain. J PainSymptom ... comorbidity. Patients with psychiatric illness may not have routine general medicalcare and diagnosis of general medical conditions may bedelayed. As the physician with the most (and often the only)...
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Báo cáo khoa học: Broad antibiotic resistance profile of the subclass B3 metallo-b-lactamase GOB-1, a di-zinc enzyme potx
... substrate. In these cases, the kcatvalues were obtained frominitial hydrolysis rates measured at saturating substrateconcentrations. All data were analysed using MicrosoftExcel and the kaleidagraph ... inactivation of wild-type and mutant GOB-1 by the chelating agent EDTA was followed using imipenem as a reporter substrate and measuring the initial rates of hydro-lysis at varying EDTA concentrations ... reverse:(5¢-GATCTTGCTGCTTACTGCGGCTCACTACGACCATACAGG-3¢)(5¢-GCACCTGTATGGTCGTAGTGAGCCGCAGTAAGCAGC-3¢)For the Q116N mutant forward and reverse:(5¢-GATCTTGCTGCTTACTAACGCTCACTACGACCATACAGG-3¢)(5¢-GCACCTGTATGGTCGTAGTGAGCGTTAGTAAGCAGC-3¢)For the...
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Báo cáo khoa học: In vitro gamma-secretase cleavage of the Alzheimer’s amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc potx
... CTFmigrating faster than C101-3FLAG as an a- CTF within27 Da of the calculated molecular mass. Finally the same line was used to predict the molecular mass of a third FLAG-reactive protein between alpha ... R, Maruyama H, Koo EH, Haass C, TakioK, Morishima-Kawashima M, Ishiura S & Ihara Y (2003) Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49–99 of beta-amyloidprecursor ... University of Melbourne and the Mental Health Research Institute, Parkville, Victoria, AustraliaGamma-secretase is an aspartyl protease that cleavestype I integral membrane proteins intramembranously.The...
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Báo cáo y học: "Randomized trial comparing daily interruption of sedation and nursing-implemented sedation algorithm in medical intensive care unit patients"
... participated in study design, data analysis and interpretation, and drafting of the manuscript. WIJ partici-pated in data acquisition and drafting of the manuscript. SKEparticipated in study ... and were not involved in the DSMB's dataanalysis. The study was not terminated because of the finding of increased hospital mortality in patients treated by DIS.CensoringThirty-six patients ... and SA.Materials and methods The study was conducted in accordance with the ethicalstandards of the Virginia Commonwealth University Institu-tional Review Board (IRB) and the Declaration of...
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