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Báo cáo khoa học: H2O2, but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae An experimental and theoretical approach pot

Báo cáo khoa học: H2O2, but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae An experimental and theoretical approach pot

Báo cáo khoa học: H2O2, but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae An experimental and theoretical approach pot

... but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae An experimental and theoretical approach Hugo Osorio1,2, Elisabete Carvalho1, ... concom-itant appearance of inosine (Fig. 1A) . Incubation timeslonger than 30 min in the presence of H2O2did not greatlychange the ratio SATP + ADP + AMP/Ino. Similarchanges in ATP and inosine ... H2O2evokes a decrease and an increase in the intracellularconcentration of ATP and inosine, respectively. Searchingfor the rationale for these phenomena, possible changes in the specific activities...
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Báo cáo khoa học: Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria doc

Báo cáo khoa học: Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria doc

... representing the mature form of the protein (Fig. 1B, lanes 2 and 3). An additional band seen after proteinase K treatmentof Cox 7a samples most likely represents a protease-resistant domain of the ... com-plex may be involved in altered complex IV assembly and human disease, and also to assess the possibleinvolvement of Surf1 in the formation and assembly of the LSI complex. BN-PAGE and western ... Massa V, Fernandez-Vizarra E, Alshahwan S, BakhshE, Goffrini P, Ferrero I, Mereghetti P, D’Adamo P,Gasparini P & Zeviani M (2008) Severe infantileencephalomyopathy caused by a mutation in...
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Báo cáo khoa học: Inhibition kinetics of catabolic dehydrogenases by elevated moieties of ATP and ADP – implication for a new regulation mechanism in Lactococcus lactis potx

Báo cáo khoa học: Inhibition kinetics of catabolic dehydrogenases by elevated moieties of ATP and ADP – implication for a new regulation mechanism in Lactococcus lactis potx

... LDH, ADH and GAPDH with ATP, ADP and the cofactor product (NAD for ADH and LDH, and NADH for GAPDH) as inhibitors. Similarly, for purified horse liver and yeastADHs, with ATP and ADP as inhibitors.I1+ ... modulated by these nucleo-tides in a nonlinear manner in many organisms. The action of an elevatedpool of ATP and ADP may effectively inactivate lactococcal ADH, but not GAPDH and LDH, providing ... of ADP + NADfor ADH, whereas there was a slight increase in inhibi-tion of ADH by the combination of ATP + NAD. The combinations ATP + NADH and ADP +NADH had a severe inhibitory effect on GAPDH,...
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Báo cáo khoa học:

Báo cáo khoa học: "Last but Definitely not Least: On the Role of the Last Sentence in Automatic Polarity-Classification" pdf

... be-tween authors’ ratings and readers’ rating for whole reviews and the correlation between au-thors’ rating and readers’ rating upon reading the last sentence are similar, while the correla-tion ... (Giora and Lee, 1996) that when the DT appears also at the end of a text it is somewhat information-ally redundant. However, functionally, it plays a role in wrapping the text up and marking ... representing the polarity of the entire posts. Then, they divided the posi-tive category into 2 sub-categories - happy and joy, and the negative category - into angry and sad. They showed that...
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Báo cáo y học:

Báo cáo y học: "TPO, but not soluble-IL-6 receptor, levels increase after anagrelide treatment of thrombocythemia in chronic myeloproliferative disorders"

... Moreover, the lack of correlation between changes of levels of the here measured cytokines with levels of anagrelide is understandable, since the varia-tion in maintenance dose was small (mean daily ... levels did not change significantly. There was no correlation between levels of anagrelide and cytokine levels at 6 months, and changes of cytokine levels did not relate to changes of platelet ... routine of the hospital laboratories of clinical chemistry. Serum and plasma samples were collected at baseline and after 6 months of therapy and stored at –70oC until analyzed. Only patients...
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Tài liệu Báo cáo khoa học: Bacitracin is not a specific inhibitor of protein disulfide isomerase pptx

Tài liệu Báo cáo khoa học: Bacitracin is not a specific inhibitor of protein disulfide isomerase pptx

... thior-edoxin-like domains, a, b, b¢, and a , a linker region xbetween the and a domains, and a C-terminal acidicextension. The a and a domains contain the CGHCactive site motif, and are sufficient alone ... Escherichia coli DsbA and DsbC,as well as the isolated catalytic a domain of PDI. Both the PDI a domain and DsbA have a catalytic site, with an associated substrate-binding site, but lack an inde-pendent ... further study the mechanism of action of bacitra-cin, the reduction of insulin was analyzed in the pres-ence of the PDI a domain and DsbA, which arecapable of catalyzing the oxidation and...
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Báo cáo khoa học: Distinct but critical roles for integrin aIIbb3 in platelet lamellipodia formation on fibrinogen, collagen-related peptide and thrombin pot

Báo cáo khoa học: Distinct but critical roles for integrin aIIbb3 in platelet lamellipodia formation on fibrinogen, collagen-related peptide and thrombin pot

... conformationalchange in the extracellular domain, leading to an increase in affinity, thereby promoting integrin–ligandinteractions [2]. In turn, clustering of integrins gene-rates a series of intracellular ... rather than the nature of the ligand medi-ating lamellipodia formation. As shown in the presentstudy, immobilized CRP and thrombin induced a much greater increase in intracellular Ca2+relative ... CD40ligand and fibronectin. Integrin a IIbb3plays a vital role in supporting platelet adhesion to the extracellularmatrix and promoting platelet–platelet interaction(aggregation). In addition, integrin...
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Báo cáo khoa học:

Báo cáo khoa học: "MIX Is Not a Tree-Adjoining Language" doc

... is a terminating rule, then a treewith a single node labeled by A( w1, w2)isaderivation tree for A( w1, w2).S(aa a aa a, #¯aa a aaa)D(aa a aa a, ¯aa a aaa)F(aa a a, a aaa) A( a, a) ... E (a a a, a aa)D (a a, ¯aa)F (a a, ¯aa) A( a, a) E( a, a) D(ε, ε) A ( a, a) D(ε, ε) A ( a, a) D (a a, ¯aa)F (a a, ¯aa) A( a, a) E( a, a) D(ε, ε) A ( a, a) D(ε, ε)C(ε, #)Figure 1: An ... LinguisticsMIX Is Not a Tree-Adjoining LanguageMakoto KanazawaNational Institute of Informatics2–1–2 Hitotsubashi, Chiyoda-kuTokyo, 101–8430, Japankanazawa@nii.ac.jpSylvain SalvatiINRIA Bordeaux Sud-Ouest,...
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Báo cáo khoa học: Lack of stabilized microtubules as a result of the absence of major maps in CAD cells does not preclude neurite formation pot

Báo cáo khoa học: Lack of stabilized microtubules as a result of the absence of major maps in CAD cells does not preclude neurite formation pot

... were stained simultaneously with anti-tubulin (DM 1A) and anti-actin (lanes 1 and 2). Other samples were stained with anti-neurofilament protein (lanes 3 and 4). The volume of each sample was adjusted ... the protein in brain samples was found in the pellet, whereas, in dCAD cells samples, no MAP bandwas observed (not shown).Gene and mRNA analyses of MAP1b, MAP2, Tau, and STOP The finding that ... lm Taxol did not cause increase of acetylatedtubulin (Fig. 1E), indicating that the acetylation stateof tubulin depends mainly on the relative activities of the acetylating and deacetylating...
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Báo cáo khoa học: NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical b-toxin sequence but with a-like physiological activity doc

Báo cáo khoa học: NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical b-toxin sequence but with a-like physiological activity doc

... rectangle the slower the exchange. Arrows indicate b-strands and zig-zaglines indicate the a- helix. (B) Ribbon diagram of Cn12 showing an a- helix at residues 24–32, three strands of antiparallel ... net increase in the inactivationtime constant. Ipeakvs. V plots obtained in the same cell in Fig. 1. Final purification and amino-acidsequence determination of Cn12. (A) A sampleof fraction ... Na+channel binding sites usinginformation from 112 Na+channel gene clones available in the literature, focusing on the extracytoplasmic loops of the S5–S6 transmembrane segments of domain I and...
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