Báo cáo khoa học: "Features and Agreement" pptx

... '/' and 'V are the standard LCG forward and backward implication operators. 7- ::= Y= + 7-^7- + 7-v7- C ::= 7- + C/C + C\¢ In general, atomic categories in a standard catego- ... straight- forwardly to the cases of coordination and morphological neutralization discussed by Zaenen and Kar- tunen (1984), Pullum and Zwicky (1986) and In- gria (1990). The nature of an appropriate ... see Shieber (1986) and Pollard and Sag (1994) for details. Then each of the follow- *We would like to thank Bob Carpenter, Pauline Ja- cobson, John Maxwell, Glynn Morrill and audiences at Brown...

Báo cáo khoa học: "PARSING AND FASY" pptx

... prncessability is dominant. Can these two functional demands be recrtnciled? There is in fact no a priori reason to believe that the demands of learnability and parsability are necessarily compatible. ... morphological and phtmological systems, and advances the notion of k.reversibility as the analog of bounded context parsability for such finite state sysiems. 1I IIOUNDED CONTEXT PARSAIflI.ITY AND ... A and learner component C, if A and C disagree on any phrase-marker b generated by B. then they disagree on some phrase-marker b generated by B, with b' ofdegree at most U. Wexler and...

Báo cáo khoa học: "Features and Values" docx

... general- ized and expanded version of a system that Stuart Shieber originally designed for the PATR-II project at SRI in the spring of 1983 with later modifications by Fernando Pereira and me. Like ... sentences like "he and I agree" the verb has the same form as in "we agree. " The morphological equivalence of "he" and I," "you and I," and "we" ... A B) inherits both negative and positive constraints of A and B. This follows from the fact that the generalization of A and B is the ma~ximal sub- graph of A and B that will unify with either...

Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx

... tumors and cell lines, miR-17-5p and miR-20a are induced in a manner that dependson cyclin D1 and repress the expression of cyclin D1.Hence, miR-17-5p ⁄ 20a and cyclin D1 form a feedbackloop and ... transcription factors E2F and Myc but,in turn, miR-17-92 downregulates the expression ofE2F and Myc [52]. In tumor progression, the tran-scription repressors ZEB1 and SIP1 and the miR-200family ... repressingthe indicated targets and presumably hundreds of other as yetunidentiﬁed targets. (B) miR-34a and the miR-34a-binding site inthe 3¢ UTR of genes shown in (A).miRNAs and cell signaling A. Ichimura...

Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of ﬂavoproteins: probes of hydrogen tunnelling pptx

... tunneling and is promoted byboth inter- and intramonomeric correlated motions. JAm Chem Soc 128, 8015–8023.26 Garcia-Viloca M, Truhlar DG & Gao JL (2003) Reac-tion-path energetics and kinetics ... J (1999) Proton and hydro-gen atom tunnelling in hydrolytic and redox enzymecatalysis. Can J Chem 77, 1085–1096.33 Bell R (1980) The Tunnel Effect in Chemistry. Chap-man and Hall, London.34 ... BuckmannAF (1989) Enzymatic-synthesis of 4R-H-2NAD(P)H and 4S-H-2NAD(P)H and determination of the stereo-speciﬁcity of 7-alpha-hydroxysteroid and 12-alpha-hy-droxysteroid dehydrogenase. Biochim...

Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

... WAF1 and MDM2 seem to beslightly more sensitive to mutations and NOXA and p53R2 slightly less so. This is indicated by the averageactivity of mutants in the central domain of 26% forWAF1 and ... middle group and the high-severity scores and thereby low activity in a thirdgroup, the mutants placed in the ﬁrst and third groupscan be expected to correlate well with high and lowactivity, ... severity scores canbe calculated for several candidate mutants and, subse-quently, the mutant(s) with the lowest score(s) can beselected. If, on the other hand, the aim is a predictionof the activity,...

Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

... insulin receptor and Grb7. A role for two of itsbinding domains, PIR and SH2. Oncogene 19, 2052–2059.36 Daly RJ, Sanderson GM, Janes PW & Sutherland RL(1996) Cloning and characterization ... procedures.Untreated and KCl-treated fractions wereassayed for Grb14, IRb and phosphorylatedIRb (p-IRb) content (B) and for ability tophosphorylate RCAM-L (C). The ﬁgureshows representative immunoblots and results ... added, and after rotatory shaking for 2 h, beadswere sedimented and washed four times in 25 mm Hepesbuffer, 100 mm NaCl, 1 mm Na3VO4 and 0.1% TritonX-100. Immunoprecipitated Grb14 and IRb...

Tài liệu Báo cáo khoa học: Gas6 and protein S Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily pptx

... expands theboundaries of signalling mediators, and it is thereforenot unlikely that Sky and Mer could be involved inTable 1. Afﬁnities of Gas6 and protein S for Axl, Sky and Mer RTKs within and ... (N-terminal segment and LG1) and green (LG2), and Axl Igdomains are in yellow (IG1) and brown(IG2); a calcium ion in the LG1–LG2 inter-face is shown as a pink sphere, and theGas6–Axl contact ... between the Axl RTK sub-family and platelet-derived growth factor receptor (Ig domains) and EphA (FNIII and Ig domains) RTKs. No similarity is shared betweenAxl and EGFR, which possesses cysteine-rich...

Tài liệu Báo cáo khoa học: Structural and biochemical characterization of a human adenovirus 2/12 penton base chimera pptx

... residues(residues 133–367) between strands D and E and asmaller insertion of  50 residues (residues 404–458)between strands F and G. The hypervariable loop,Table 1. Data collection and reﬁnement statistics ... expression, the SF21 and Hi5 cell lines and the Bac-to-Bac expression system and vectors were fromInvitrogen (Carlsbad, CA, USA). Protease inhibitors werefrom Roche (Basel, Switzerland) and Ni-NTA resin ... domain formed by two b-sheets and a distal domain formed by insertions between thestrands of the jellyroll domain (Fig. 3). Antiparallelb-sheets made up of strands CHEF and BIDG packagainst each...

Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx

... (APs; EC 3.4.23) have been extensivelystudied and characterized and are widely distributed amongvertebrates, plants, yeast, nematodes, parasites, fungi and viruses [1,2]. AP activity has also been ... differentclans based on their evolutionary relationship and tertiarystructure. Plant APs have been distributed among familiesA1, A3, A11 and A12 of clan AA, and family A22 of clanAD. The majority of plant ... prosegment and the active site render the prosegment more ﬂexible and enable the substrate to enter the catalytic cleft. Nevertheless,only the structural characterization of procardosins and Fig....

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