Báo cáo khoa học: "Machine-Learning-Based Transformation of Passive Japanese Sentences into Active by Separating Training Data into Each Input Particle" ppt

Báo cáo khoa học: "Machine-Learning-Based Transformation of Passive Japanese Sentences into Active by Separating Training Data into Each Input Particle" doc

... could not improve the rate of ac-curacy.5 Method of separating training data into each input particleWe develo ped a new method of separating train-ing data into each input (source) particle ... particles when trans-forming Japanese passive sentences into active sentences. It separates training data into each input particle and uses machinelearning for each particle. We also usednumerous ... ques-tion. Methods of transforming passive sentences into active are important in natural language pro-cessing.The transformation of case particles in trans-forming passive sentences into active is...

Báo cáo khoa học: "Machine-Learning-Based Transformation of Passive Japanese Sentences into Active by Separating Training Data into Each Input Particle" ppt

... 10% of all texts, wererandomly taken to obtain test data. The rest of texts were used to generate training data. We evaluated performance of prediction by ac-curacy. We deﬁned accuracy by the ... accuracy by the ratio of thenumber of correct predictions to that of instances of the target noun in the test data. 5.2 Experimental ProceduresFirst, we generated training data for each targetnoun ... their heads. Of the extracted instances, we excluded those that hadno contextual cues from the training data (and alsothe test data) . We also generated another set of training data by removing...

Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf

... the conformationaround the active site of ApeSOD is independent of the presence of a metal cofactor.Figure 3D shows the superimposition of the active site structures of apo, Mn-bound and Fe-bound ... (Fig. 3A). Three of the ligands,OD2 of Asp165, NE2 of His79 and NE2 of His169,formed an equatorial plane. The other protein ligand,NE2 of His31, bound to the metal, in the company of a water oxygen, ... structure of ApeSOD. In particular, we focuson the coordination of the metal cofactor in the active site as well as the changes it experiences in response todifferent metal cofactors. Finally, by...

Tài liệu Báo cáo khoa học: Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT–MIM interaction pptx

... inserted into the BamHI–EcoRIsites of pGST–pHis, a cDNA fragment encoding aminoacids 1–165 of calpain 7 (calpain 7MIT) was ampliﬁed by using a pair of primers (forward, 5¢-GAGAGATCTEnhancement of ... analyzed by WB withmAb against GFP to compare the electrophoreticmobility of 30 K with that of each mGFP construct. Asshown in Fig. 6D, the electrophoretic mobility of 30 Kwas closer to that of ... were proba-bly derived by limited digestion with other cellular pro-teases, and not by autolysis of mGFP–calpain 7.Enhancement of autolysis of mGFP–calpain 7–Strep by GST–MIM in vitroAs we...

Tài liệu Báo cáo khoa học: Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites doc

... (Met1) of Tat(1–9) andAsp709 as well as Asp739 of DP IV, between the C-terminalGlu9 of Tat(1–9) and the side chains of Arg560 and Lys554 of DP IV. Furthermore, the side chain of Asp5 of Tat(1–9) ... carbonyl group of Asn7 of Tat(1–9) and theside chain of Lys554 of DP IV and finally, between thecarbonyl group of Ile8 of the peptide interacting with theTyr752 hydroxyl group of the enzyme. ... both at the active siteand at an additional binding site. Binding of one inhibitormolecule out of the active site, here defined by the Kivalue,decreases the affinity for binding of the substrate....

Báo cáo khoa học: Catalytic digestion of human tumor necrosis factor-a by antibody heavy chain pot

... conformation of ETNF-6mAbSequencing of the cDNA of the variable region of ETNF-6 mAb was performed, and this was followed by molecular modeling of its three-dimensional struc-ture. The heavy chain of ... the Ser5-Arg6 bond of TNF-a at the ﬁrst step, resulting in the generation of a fragment of  17 kDa. This fragment was digested to a smaller molecule of 15 kDa by scission of the Gln21-Ala22 ... reaction time of 47.2 h, the amount of TP41-1 at aretention time of 11 min decreased, because of frag-mentation. The fragment was observed at a retentiontime of 13 min (indicated by an arrow)...

Báo cáo khoa học: Selective inhibition of ADAMTS-1, -4 and -5 by catechin gallate esters ppt

... addition of type-specific covalentinactivators of serine and cysteine proteinases, the lack of cleavage of a quenched fluorescence substrate sensitive tohydrolysis by matrixins, the detection of aggrecan ... a representative of the ADAM group of metalloproteinases. Statisticallysignificant inhibition of the collagenases by any of thecatechins or gallates required a concentration of at least20 lM. ... 7.5). Active fractions were elutedbetween 0.2Mand 0.45MNaCl on a salt gradient andwere pooled. The purity of the enzyme preparations wasassessed by SDS/PAGE followed by silver staining of...

Báo cáo khoa học: "Conceptual Analysis of Garden-Path Sentences" ppt

... in a number of ways, the simplest of which is the notion of one word preceding or following another. Such information is encoded as a positional predicate in the test of a type of production ... restrictions by dividing the test part of request into a number of facets. There are three reasons for doing this. First, it allows for a distinction between different kinds of knowledge. ... " ;by& apos;, etc. [The usage of "subject" is incorrect in the usual sense of the word.) The Time facet of REQ2a states that the request should be considered only after the type of...

Báo cáo khoa học: The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors ppt

... hyperphosphorylated form, by a positive effect caused by accumulation of thehypophosphorylated form or by a combination of the two mechanisms, in keeping with the self-regulation of the Rb gene by its own ... effect of UCN-01 on the levels of Rbprotein may be caused by an increase in the synthesis of Rband by a decrease in its degradation. However, the effect onSp1 could be accounted for by the ... activityincreases the expression of Rb and Sp1.Fig. 1. Eﬀects of UCN-01 on the levels of Rb and Sp1 protein. (A), (B) Dose–response of the eﬀect of UCN-01 on the levels of retinoblastoma geneproduct...

Báo cáo khoa học: Crystal structure of Thermoanaerobacter tengcongensis hypoxanthine-guanine phosphoribosyl transferase L160I mutant ) insights into inhibitor design potx

... N-terminus of each subunit of the tetra-mer forms crystal contacts with the active site of asubunit of the neighboring tetramer. As a result, onetetramer links to four other tetramers via the active site ... L160Imutant. (A) Each subunit of a tetramer (red)links its N-terminus to the active site of aneighboring tetramer subunit (green).(B) Stereo diagram of the crystal packingarrangement of the tetramers. ... The crystal structure of the L160Imutant of T. tengcongensis HGPRT was determined at1.7 A˚resolution. Unexpectedly, the enzyme active sitewas occupied by the N-terminus of a neighboring pep-tide....

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