Báo cáo khoa học: "Hunting for the Black Swan: Risk Mining from Text" doc

... AlertingNotiﬁcation Risk Taxonomy Risk Mining for Risk IdentiﬁcationInformation Extraction for Risk MonitoringFigure 2: The risk mining and monitoring systemarchitecture The second part of the system, the Risk Mon-itor, ... and the types of risk they are facing, together with bub-ble sizes proportional to the number of alerts that the Risk Monitor could discover in the corpus. The second option also permits the ... Proceedings of the ACL 2010 System Demonstrations, pages 54–59,Uppsala, Sweden, 13 July 2010.c2010 Association for Computational LinguisticsHunting for the Black Swan: Risk Mining from TextJochen...

Tài liệu Báo cáo khoa học: "Methods for the Qualitative Evaluation of Lexical Association Measures" doc

... the respective SL, while the -axis represents the precision (or recall) valuesachieved. For instance, the precision values for and for the AdjN data can beread from the -axis in Figure 1 at ... precision values above50% for the ﬁrst 10% of the list, but is outper-formed by the t-test afterwards. Looking at the ﬁrst 40% of the data, there is a big gap between the good measures (t-test, ... stated at the be-ginning of this section, the performance ofand relative to the other AMs is not better for high-frequency data than for low-frequency data.Instead, the poor performance observed...

Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt

... [9,19,24,25]. The main goal of the present study was to investi-gate further the resemblance between hcHAT proteinsand the enzymes from the a-amylase family. We there-fore carried out a bioinformatics ... knowl-edge, from Urochordata (Fig. 1). The second sequence feature clearly visible from the alignment is whether the individual catalytic residues,or even the entire catalytic triad of the GH13 ... and for rBAT also with the short stretch near the C-terminusof domain B [9,19]. From the sequence–structure pointof view, the basic difference between rBAT and 4F2hcis that rBAT possesses the...

Tài liệu Báo cáo khoa học: Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina doc

... genomic DNA. For that rea-son, we amplified the open reading frame from cDNA. For the second of the two potential glycerol dehydro-genases, we predicted no introns and therefore ampli-fied the open ... protein was purified and then used for furtheranalysis.In the reductive reaction, the Michaelis–Menten con-stant Km for DHA was 1 mm, and the Km for NADPH was 50 lm. The Vmaxwas estimated ... USA)three times for 30 s. The mixture was then centrifuged inan Eppendorf microcentrifuge at full speed for 25 min, and the supernatant used for the analysis. The protein contentof the extract...

Báo cáo khoa học: Evidence for the presence of ferritin in plant mitochondria pdf

... Table 2. The theoric molecular mass, 23.6 kDa,calculated from the database sequence after removal of the N-terminus signal peptide, is in agreement with the value of25–26 kDa estimated from the ... activation of the iron trans-port systems [37]. Therefore, they are crucial in controllingiron storage and homeostasis in the plant cells. Otherfunctions of plant ferritins are, on the other hand, ... that the proteins AtFer1–4 possess at the N-terminus the typical presequences of the chloroplastic protein transit peptide [28], similarly to whatreported for pea ferritin [29,30]. On the other...

Tài liệu Báo cáo khoa học: Properties of the recombinant glucose⁄galactose dehydrogenase from the extreme thermoacidophile, Picrophilus torridus ppt

... cleft, the putative catalytic zinc being at the bottom of the cleftand a lobe containing the structural zinc at the mouthof the cleft and thus exposed to the solvent [8]. Grad-ual depletion of the ... cata-lytic site, similar to the glucose dehydrogenase enzymes from yeast andThermoplasma acidophilum. Strikingly, NADPH, one of the products of the GdhA reaction, is unstable under the conditions thought ... toexplain the dual cofactor speciﬁcity of the enzyme from T. acidophilum.Cloning and expression of the P. torridus glucosedehydrogenase genePrimers were constructed using the data of the com-plete...

Báo cáo khoa học: "Searching for Topics in a Large Collection of Texts" doc

... while the other iscalled exhaustivity of cut, which is defined as. Both functionsare positive.Thus, the specificity of cut can be formalizedby the following formula— the greater this value, the ... membership of a documentin a concept-formative clusteris a function : . For we definewhere is a constant. For we define. The following holds true for any concept--formative cluster and any document ... The cosine similarity wasused to compute the document similarity; thresh-old was . There were edges in the graph of the collection.We had computed a set of concept-formativeclusters and then...

Báo cáo khoa học: Characterization of the cofactor-independent phosphoglycerate mutase from Leishmania mexicana mexicana docx

... or afterpreincubating the enzyme with the metal for 15–30 min at the con-centrations indicated (black line). All assays were performed for the forward reaction, using the NADH oxidation method. ... was corrected manually using the information from the CLUSTALXmultiple alignment. Then the L. mexicana sequence was threaded into the structuresof the B. stearothermophilus enzyme cocrystallized ... and human PGAM offergreat promise for the design of inhibitors with highselectivity for the parasite’s enzyme. Therefore, this ﬁndingshould aid in the search for new drugs that are neededagainst...

Tài liệu Báo cáo khoa học: Upregulation of the a-secretase ADAM10 – risk or reason for hope? docx

... of intervention within the biosyntheticpathway of ADAM10 is provided by directly interfer-ing with the expression of the gene for ADAM10: the promoter region of the gene for ADAM10 has beencharacterized ... partially penetrant, theseresults give support to the hypothesis that the humangene for ADAM10 plays a role in the aetiology ofAD.ADAM10 and tumour necrosis factor a(TACE): the ill-matched coupleThree ... whether solubleADAM10 and the transmembrane variant cleave the same substrates and whether they have the same cata-lytic properties in vivo, this type of regulation has tobe elucidated further....

Tài liệu Báo cáo khoa học: Myristoylation of the dual-speciﬁcity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis pdf

... attached to the culture dish. Furthermore,cells expressing the JSP1-G2A mutant remainedattached to the dish despite the fact that the mutantprotein was expressed at similar levels to those of the wild-type ... 293T cells as the expression system, as the presence of the SV40 largeT antigen in these cells enhances their resistance toapoptosis.Apoptosis is a tightly regulated mechanism for the disposal ... sites in the cytoplasm, and was excluded from the nucleus, JSP1-G2A was uniformly distributed through-out the cell. Cells transfected with a control GFPexpression plasmid displayed a uniform distribution...

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