Báo cáo khoa học: "Is the Generally Accepted Strategy of Machine-Translation Research Optimal?" ppt

Tài liệu Báo cáo khoa học: "Is the End of Supervised Parsing in Sight?" pdf

... derivations, the probability of a tree is the sum of the probabilities of the derivations producing that tree. The probability of a derivation is the product of the subtree probabilities. The original ... consists of the computation of the shortest derivations and the extraction of subtrees, UML-DOP involves iterative training of the parameters. Once we have extracted the STSG, we compute the most ... maximizing the joint probability of their shortest derivations (i.e. the derivations consisting of the fewest subtrees). This assumption is in consonance with the principle of simplicity, but there...

Báo cáo khoa học: Epl1, the major secreted protein of Hypocrea atroviridis on glucose, is a member of a strongly conserved protein family comprising plant defense response elicitors potx

... 32]+). Although the information con-tent of the PMF based on the number of detected pep-tides was high with respect to the size of the protein(five detected peptides out of seven theoretical pep-tides), ... strands, and the black line indi-cates coiled, unstructured regions. The bars at the location of the corresponding amino acids indicate the confidence of the second-ary structure prediction. The vertical ... shown).Identification of the two major components of the secretome on glucose via cross-speciesidentificationFor protein identification of spots g1 and g2, the spotswere cut out of the gels and digested...

Báo cáo khoa học: Comparing the substrate speciﬁcities of cytochrome c biogenesis Systems I and II docx

... observationregarding the substrate speciﬁcity of the Ccm system.Neither single-cysteine holocytochrome c550wasdetected with the coexpression of the System II plas-mid, as shown in the spectra of the periplasmicextracts ... to reduce the cysteine thiols in the cytochrome heme-binding motif (neither ResA of System II nor CcmG of System I are present), the effect of the addition of a chemical reductant to the growth ... revealed the production of spectroscopically detectable AXXCH above the level of spontaneous cytochrome formation in two of the cultures. These data are responsible for the apparentformation of AXXCH...

Báo cáo khoa học: Unravelling the functional interaction structure of a cellular network from temporal slope information of experimental data docx

... fij> 0 then we interpret that the node j activates the node i by increasing the net rate of xiand if fij< 0 then the node j inhibits the node i.We note that the dynamics of the system ... results. On the otherhand, for identiﬁcation of the sign of f11, we needto consider another time interval in which we canidentify the remaining impossible sign combinations of f11, f12.Guidance ... interaction’) for the unknown sign of fij. We can then obtain the feasiblenetwork signs (FNS) at xiby excluding the INS from the all network signs (ANS) as a complementary set of the INS in ANS...

Báo cáo khoa học: "Relieving The Data Acquisition Bottleneck In Word Sense Disambiguation" ppt

... contexts are added to the seed corpus. The words in the contexts of the seed words retrieved arethen disambiguated. The disambiguated contextsare then used for querying the Web for yet moreexamples, ... scores of — the ﬁrst 16 nouns inTable 2 for — the overall potentialprecision of is signiﬁcantly increasedto 63.8% and the overall precision of is increased to 68.4%.8These results support the ... when the number of senses in-creases, PR tends to decrease.5.2 Number of Training ExamplesThis is a characteristic of the training data. We ex-amine the correlation between the PR and the...

Báo cáo khoa học: "On the Evaluation and Comparison of Taggers: the Effect of Noise in Testing Corpora." doc

... the error commited by the tagger is other than the error in the test corpus, but wrongly evaluated as right (false positive) if the error is the same. Table 1 shows the computation of the ... state than one of the taggers performs better than the other when the two intervals overlap, since this implies a chance that the real performances of both taggers are the same. The following ... better than another using noisy test corpus, there are reasonable chances that they are in fact very similar but one of them is just adapting better than the other to the noise in the corpus....

Tài liệu Báo cáo khoa học: Pharmacologic chaperoning as a strategy to treat Gaucher disease ppt

... reduc-tion therapy [11]. The premise behind this strategy isthat intralysosomal glucosylceramide accumulation willoccur in individuals where the amount of substrateexceeds the capacity of the endogenous ... approach. The promise of the pharmacologicchaperone strategy for GDPharmacologic chaperones penetrate the plasma mem-brane and the ER, and by binding to the folded mutantGC enzyme population in the ... which arerecycled in the cytoplasm. Mutations in both alleles of GC sometimes result in the accumulation of glucosyl-ceramide in the lysosomes of monocyte-macrophagecells, often leading to hepatomegaly,...

Báo cáo khoa học: In situ proton NMR analysis of a-alkynoate biotransformations ppt

... However, while protons from the solvent are incorporated in the course of the pathway, the metabolites can be detected and identiﬁed. Therefore adetailed determination of the metabolic process is ... [1]. Inaddition to these natural compounds, several syntheticchemicals contain triple bonds. The amount of theseproducts released to the natural environment in the form of drugs, pesticides, ... isshowninFig.4.Biotransformation of 2-butynedioate The UV spectrophotometric analysis of the 2-butynedioatemetabolism provided scattered absorptions at kmax¼265 nm during the ﬁrst 24 h of the biotransformation.Furthermore...

Báo cáo khoa học: Betaine protects urea-induced denaturation of myosin subfragment-1 pptx

... The inhibition of catalytic activity was counteracted by methylamines.With the aim of comprehending the effects of urea on the catalytic (globu-lar) portion of myosin, this study examines the ... obtained in the absence of betaine (P > 0.05,Student’s t-test). The center of mass of the intrinsicﬂuorescence spectrum is not affected by urea up to4 m, being shifted to the red region of the ... which no changes are observed in the center of mass [7–12,16]. Nevertheless, the attenuation of the ﬂu-orescence intensity is generally correlated with the exposure of protein tryptophan residues...

Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx

... reduced the degree of [3H]daunomycinbinding to ABCG2R482G, thus warranting furtherexamination of the effect of these nucleotideanalogues. Figure 3 shows the effects of a range of ATP-c-S ... potency. Figure 1B dem-onstrates the ability of the nucleotides to reduce the fraction of [3H]daunomycin bound to ABCG2R482G.In the presence of AMP, the binding of [3H]daunomycinremained at ... whether the binding of nucleotide to ABCG2R482Gwas the power stroke required to switch the conﬁgura-tion of the drug binding site(s). This hypothesis wasexamined using a direct measure of...

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