Báo cáo khoa học: "The Morphological Abstraction of Russian Verbs" doc

... (Matrix of Alternations) 62 [Mechanical Translation, Vol.6, November 1961] The Morphological Abstraction of Russian Verbs by Milos Pacak*, assisted by Antonina Boldyreff, Institute of ... continuation of an earlier study* of Russian morphology as prescribed by the demands of machine translation. There are three main reasons why it has been found necessary to handle the morphology of Russian ... establishment of distribution classes of Rus- sian verb-base alternants in terms of sets of paradig- matic suffixes should demonstrate the usefulness of the suggested procedure. The listing of pertinent...

Tài liệu Báo cáo khoa học: The social life of ribosomal proteins doc

... Positions of S2, S13, S16, S17, S19 and S21 inthe 30S ribosomal subunit of Escherichia coli. J MolBiol 200, 65–87.19 Stoffler G & Stoffler-Meilicke M (1984) Immunoelec-tron microscopy of ribosomes. ... rRNAs of the ribosomes in all kingdoms of life. Following the determination of the complete crystal structures of both the large and small ribosomal subunits from bacteria, the functionalrole of ... lack of a globular proteinfold (Fig. 2B). Towards the end of the ‘presubunit era’the first examples of structures of isolated protein–rRNA complexes representing important subdomains of the...

Báo cáo khoa học: "The Linguistic Basis of Text Generation" doc

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Báo cáo khoa học: "The clinical value of daily routine chest radiographs in a mixed medical–surgical intensive care unit is low"

... performance of a bronchoalveolar lavage for culture,or start of or a change in antimicrobial therapy in case of unex-pected infiltrates on the CXR; repositioning of tubes in case of malposition of orotracheal ... ultrasound of the thorax in case of pleural effusion onthe CXR, start or change in medication (diuretics); insertion of a pleural drain; and repositioning of devices in the case of mal-position of ... andmalposition of the orotracheal tube (32 in 26). Fewer than half of the CXRs with a new and unexpected finding were ultimatelyclinically relevant; in only 2.2% of all daily routine CXRs (6.4% of patients)...

Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... Expression of SV40 T antigen in promoter-reporter assays yieldedderegulation, which was dependent on the CDE of thehuman Cdc25C promoter. Dimethyl sulfate footprint-ing of the CDE in the presence of ... footprinting.Loss of the two pocket proteins leads to deregulation of the B-Myb promoter during the cell cycle. Re-intro-duction of p107, and to some extent also p130, causesrepression of the B-Myb ... these factors.Consistent with a function of p107 and p130 in thecontrol of CDE ⁄ CHR promoters is the loss of regula-tion observed for the expression of cyclin A, B-Myband Cdc2 in p107) ⁄...

Tài liệu Báo cáo khoa học: The capsid protein of human immunodeﬁciency virus: intersubunit interactions during virus assembly doc

... indicate that poly-merization of Gag occurs mainly through the forma-tion of an intermediate layer of cup-shaped structures,each made of one hollow hexameric ring of CAdomains placed immediately ... pseudoatomic models of capsid-like particles [30,39]; (b) analyses of the effect of CA mutations on the assembly of mature capsid-like particles (Fig. 2E,F) and ⁄ or the formation of viralcores; ... of the precise residues and interac-tions involved in the NTD–CTD interface [46]. Most of these involve side chains from helix 8 of the CTDwhich pack against the N-terminal end of helix 4 of the...

Tài liệu Báo cáo khoa học: The capsid protein of human immunodeﬁciency virus: designing inhibitors of capsid assembly ppt

... mature capsid of human immunodeﬁciency virus, HIV-1, is formed bythe assembly of copies of a capsid protein (CA). The C-terminal domain of CA, CTD, is able to homodimerize and most of the dimerization ... shifts of the whole dimer-ization helix of CTD [27] (otherwise, those chemicalshifts are too broad to be observed because of thepresence of interconverting conformers) [29]. The bind-ing site of ... ring of CAP-1 inserts; the urea and dimethyla-monium groups of CAP-1 also make contacts with theside chains and ⁄ or backbones of several residues in theprotein. Thus, most of the contacts of...

Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

... biological function of the pro-form of bone morphogenetic protein-2 (BMP-2), a member of the transforminggrowth factor b (TGFb) ⁄ BLP superfamily. The role of the 263 amino acids of the pro-peptide ... experi-ments demonstrate binding of proBMP-2 tothe ECD of BMPR-IA. Interaction of BMP-2(A) and proBMP-2 (B) with immobilized ECD of BMPR-IA. Interaction of BMP-2 (C) andproBMP-2 (D) with ... effect of BMP-2 and proBMP-2 on the phosphorylation status of p38 was tested, addition of BMP-2 resulted inmaximal phosphorylation of p38 after 60 min, whileproBMP2 showed no induction of p38...

Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

... understanding of the ACMSDcatalytic mechanism is still incomplete. In light of thereported ACMSD upregulation in the liver of streptozotocin-induced diabetic rats and the suppres-sion of such elevation ... withArg47 (distance of 3.0 A˚), an electrostatic interactionwith the Zn2+ion (closest distance of 4.1 A˚) and anextensive network of hydrogen bonds involving a set of well-ordered solvent ... structure of hACMSD in complex with DHAPmay used for the design of potent and highly selectiveenzyme inhibitors that may prove to be of potentialinterest to reduce life-threatening complications of cerebral...

Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

... 100 lm of (GlcNAc)1–4was analysed at thestart, in the middle and at the end of each series of sam-ples. The resulting average values of the standards (display-ing standard deviations of < ... 4MU-(GlcNAc)2assubstrate; 50 lL of supernatant was mixed with 50 lLof50 mm citrate–phosphate buffer, pH 3.8, containing 50 lm of substrate and 0.1 mgÆmL)1 of bovine serum albumin,giving a ﬁnal volume of 100 lL. ... Reaction mixtures contained 1 lm of LlChi18A and ⁄ or 3 lm of LlCBP33A, 0.1 mgÆmL)1 of puri-ﬁed bovine serum albumin, 0.1 mgÆmL)1 of b-chitin powderor 0.5 mgÆmL)1 of a-chitin powder, in 50 mm...

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