... presence of this enzyme in different tissues with properties of endothelial NOS, nNOS, and ⁄ or iNOS [14,31,32]. Indifferent models of sepsis and tissues, the existence of both mtNOS and i-mtNOS isoforms ... formation of O2–through the partial reduc-tion of oxygen by one electron. Subsequent reduction by one or two electrons can yield H2O2, and HO, respect-ively [46]. However, the main source of ... designer software(Premier Biosoft Int., Palo Alto, CA, USA) and obtainedfrom Thermo Electron GmbH (Ulm, Germany). Real-timePCR reactions were carried out in a final volume of 25 lL of reaction...