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Báo cáo khoa học: Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost fish Cyprinus carpio pot

Báo cáo khoa học: Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost fish Cyprinus carpio pot

Báo cáo khoa học: Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost fish Cyprinus carpio pot

... Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost fish Cyprinus carpio Margarita I. Concha1, Valerie J. Smith2, Karina Castro1, ... 2004 ApoA-I and apoA-II in innate immunity of the carp (Eur. J. Biochem. 271) 2987Fig. 4 B, t he inta ct a poA-I (b and a), an intermedia ryfragment (band b) and a more stable third band (band ... among other things, the need of teleost fish to rely more on their innate immunity forsurvival. As we described previously [8], apoA-I and apparently also apoA-II are locally synthesized and secretedin...
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Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

... (F340) increases, whereas the fluorescence intensity at 380 nm (F380) decreases upon the binding of Ca2+. The change in the ratio of F340 ⁄ F380 determined the change in Ca2+concentrationinside ... Ca2+⁄CaM-binding IQ domain that is involved in the activa-tion of Ras-GRF1.Stimulation of all the splice variants of the Gs-coupledserotonin receptor 5-hydroxytryptamine7(5-HT7)increases intracellular ... to N-terminal deletions of the full-length 140 kDa protein. The physiological role of the guanine nucleotide exchange activity of the truncatedforms is not known as they are missing the Ca2+⁄CaM-binding...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "Universal Grammar and Lexis for Quick Ramp-Up of MT Systems" doc

... ernment and binding (Chomsky 1981), principles and parameters (Chomsky 1986) and the minimal- ist position (Chomsky 1995). The theory postulates a small number of general principles defining the ... list of parameters in the single-TL environment is facilitated not only by the availability of the initial set of lexical parameters but also by the prominence of the syn- 977 tactic and ... acquisition in Boas, both in terms of resources cre- ated and reused and in terms of the actual elicita- tion techniques, differentiating between the acquisition of grammatical and lexical...
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Báo cáo khoa học: 3 Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines potx

Báo cáo khoa học: 3 Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines potx

... villi (the intervillus e pithelium), where the proliferating cells of the intestinal epithelium are localized (Fig. 5A). Geminin mRNA has a distributionsimilar to Cdt1 in the small and large intestine. ... [17]. We investigated the in vivo expression of Cdt1 and compared it t o that o f geminin in the d evelopingmouse gut epithelium, a tissue in which a p roliferating and adifferentiating z one ... pecific for the human gemin in g ene w ere g enerated by random primingusing the complete open reading frame of the humangeminin cDNA. A probe directed against the actin mRNAserved as a loading control....
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Báo cáo khoa học: A new and efficient method for inhibition of RNA viruses by DNA interference pptx

Báo cáo khoa học: A new and efficient method for inhibition of RNA viruses by DNA interference pptx

... 3¢-overhangs of two nucleotides are incor-porated into RNA-induced silencing complex (RISC),where they unwind, and an antisense strand of siR-NA (guide strand) then binds to the complementaryRNA. ... multidomain members of the RNase III fam-ily that are responsible for processing long dsRNAsinto effector siRNAs. Human Dicer contains a singlePAZ domain, a single dsRNA-binding domain, and ATPase ... processeddsDNA, which suggests activation of the cellular machinery involved in silencing of RNA. For the silencing of viral RNA effected with dsDNA,we coined the term DNA interference technology.AbbreviationsAgo,...
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Báo cáo khoa học: Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis pdf

Báo cáo khoa học: Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis pdf

... dissociation of these twoproteins inhibits the antiapoptotic activity of Bcl-2 byinitiating the release of cytochrome c from mitochon-dria into the cytosol and increasing the activities of caspase 3 and ... cl-1,Bcl-B and A1. The proapoptotic proteins are dividedinto two distinct groups: the multidomain proteins,containing three BH domains (Bax, Bak and Bok); and the BH3-only proteins (Bad, Bid, Bim, ... and other close Bcl-2 homologs, such asBcl-xL and Mcl-1 [45]. Mutation of the BH3 domain of Beclin 1 or of the BH3 receptor domain of Bcl-2 ⁄Bcl-xL abolishes their capacity to inhibit Beclin1-dependent...
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Báo cáo khoa học: PKA independent and cell type specific activation of the expression of caudal homeobox gene Cdx-2 by cyclic AM pptx

Báo cáo khoa học: PKA independent and cell type specific activation of the expression of caudal homeobox gene Cdx-2 by cyclic AM pptx

... allele be insufficient in maintaining itsown expression in the intestinal nonendocrine cells, and in preventing the formation of intestinal polyps for the nonendocrine intestinal epithelia?We ... Cis-Acting elements and tran-scription factors involved in the intestinal specificexpression of the rat calbindin-D9K gene: binding of the intestine-specific transcription factor Cdx-2 to the TATA ... normalintestinal epithelia continues [8,9]. However, the expression of both Cdx-2 and proglucagon in the endocrine cells of both pancreatic and intestinal originappears to be unaltered in the...
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Tài liệu Báo cáo khoa học: A second novel dye-linked L-proline dehydrogenase complex is present in the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 pptx

Tài liệu Báo cáo khoa học: A second novel dye-linked L-proline dehydrogenase complex is present in the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 pptx

... at the interface between the a and b subunits.A comparison of the amino-acid sequences showed that the ADP-bindingmotif in the a subunit of PDH1 clearly differs from that in the a subunit of ... stream from the 5¢-terminus of the predic-ted ORF, is the proper initial codon for a2. The N-ter-minal amino-acid sequences of the b2 and c2 subunitscorresponded to the sequences of the predictedPH1751 ... show the amino-acidalignment of the a and b subunits of PDH1, PDH2 and T. profundus dye-l-proDH. The amino-acid sequence of the a1 subunit of PDH1 showed 31% and 32% identi-ties with the a2...
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Báo cáo khoa học: Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA potx

Báo cáo khoa học: Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA potx

... pair of rare AGAAGG codons has been demonstrated in a natural gene and ribosome stalling and drop-off at a pair of argin-ine codons in mini-genes [19]. In the present study we show that the ... inhibitgrowth of the strain even in the presence of IPTGinduction. All of these results suggest that the low geneexpression associated with NGG codons in the down-stream region following the initiation ... paus-ing at early NGG codons is the reason for the observed low gene expression. The length of the peptidyl moiety of the peptidyl-tRNA in uences the drop-off process in the case of very small mini-genes...
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Báo cáo khoa học: Activated transglutaminase from Streptomyces mobaraensis is processed by a tripeptidyl aminopeptidase in the final step pptx

Báo cáo khoa học: Activated transglutaminase from Streptomyces mobaraensis is processed by a tripeptidyl aminopeptidase in the final step pptx

... Ne-(c-glutamyl)lysine bonds, the incorpor-ation of polyamines into proteins, the deamidation of protein-bound glutamines, and the covalent attachment of proteins to lipids such as x-hydroxyceramides ... nucleases and proteases, the functions of which are not well under-stood. It would appear that they have more important roles in regulating cellular differentiation over and above the mere digestion of ... distinct differ-entiation stages. Culture on agar plates containing glucose,yeast and malt extracts allows the organism to developsubstrate and aerial mycelia culminating in the formation of spores...
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