... synthase gene; Gb4, globotetraosylceramide (GalNAcb1,3Gala1,4LacCer); GD 1a, NeuAca2,3Galb1,3GalNAcb1,4(NeuAca2,3)LacCer; GD1b, Galb1,3GalNAcb1,4(NeuAca2,8NeuAca2,3)LacCer; GM1, Galb1,3GalNAcb1,4(NeuAca2,3)LacCer; ... forward primer 5¢-CGTCCCCACAATCGGTGTCA-3¢ and the reverse primer5¢-ACCACTCCCTCTTTGACCAG-3¢; for GAPDH, the forward primer 5¢-CCACCCATGGCAAATTCCATGGCA-3¢ and the reverse primer 5¢-TCTAGACGGCAGGTCAGGTCCACC-3¢. ... From these observations, wereasoned that the transcriptional inhibition of Gb3Smay be an effective means of treatment of Gb3-relateddiseases.Previously, we have identified and characterizedthe...