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Báo cáo khoa học: Yeast oxidative stress response Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state pot

Báo cáo khoa học: Yeast oxidative stress response Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state pot

Báo cáo khoa học: Yeast oxidative stress response Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state pot

... 2006 The Authors Journal compilation ª 2006 FEBS Yeast oxidative stress response Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state Ana P. D. Demasi1, ... function, is probablyinvolved with its specific role in the antioxidant defense of yeast with mitochondrial dysfunction.cTPxI influences the expression of genes involvedin yeast oxidative stress response: ... dehydrogenase, mitochondrial isocitrate de-hydrogenase, glutathione peroxidase III, heat shockprotein 104, thioredoxin peroxidase II, catalase A, nuc-lear thioredoxin peroxidase, thioredoxin I and glutare-doxin...
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Báo cáo khoa học: Exogenous oxidative stress induces Ca2+ release in the yeast Saccharomyces cerevisiae potx

Báo cáo khoa học: Exogenous oxidative stress induces Ca2+ release in the yeast Saccharomyces cerevisiae potx

... Transcription factors regulat-ing the response to oxidative stress in yeast. AntioxidRedox Signal 4, 123–140.25 Ikner A & Shiozaki K (2005) Yeast signaling pathwaysin the oxidative stress response. ... contribution of E. Mar-tegani and R. Tisi (Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan,Italy) to the manuscript. This work was supported by the Ministry of Education ... calmodulin, which can bind and activate calcineurin; this inhibits, at the post-tran-scriptional level, the function of Vcx1p [11,15,16] and induces the expression of PMC1 and PMR1 genes viaactivation...
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Tài liệu Báo cáo khoa học: Yeast glycogenin (Glg2p) produced in Escherichia coli is simultaneously glucosylated at two vicinal tyrosine residues but results in a reduced bacterial glycogen accumulation docx

Tài liệu Báo cáo khoa học: Yeast glycogenin (Glg2p) produced in Escherichia coli is simultaneously glucosylated at two vicinal tyrosine residues but results in a reduced bacterial glycogen accumulation docx

... unambiguousidentification of the glucosylation sites in Glg2p. However, the different modes of action o f the two hydrolases result i nno obvious physiological implications. The degree to which the ... Thus, the precise function of the multiple tyrosineresidues remains to be clarified.In this communication, we have expressed one of the t wo yeast glycogenins, Glg2p, in E. coli. Functionality of ... recently identified that interacts with the mamma-lian glycogenin and thereby enhances the self-glucosylatingactivity [14,15].In prokaryotes the initiation of glycogen b iosynthesis hasnot...
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Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

... to domains I and II. In this case, the EGFR tyrosine kinase is acti-vated constitutively without ligand binding, as in the case of EGFR vI. EGFR vIII is reported to occur in30–50% of glioblastomas ... as in the case of activation of cyclin-dependent kinases by cylclins. Dimerization con-sequently stimulates intrinsic tyrosine kinase activity of the receptors and triggers autophosphorylation ... tyrosine kinase activity because of substitutionsin crucial residues in the tyrosine kinase domain. How-ever, it has many binding sites for p85, a regulatorysubunit of phosphatidylinositol 3-kinase,...
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Báo cáo khoa học: Cotton GhMPK2 is involved in multiple signaling pathways and mediates defense responses to pathogen infection and oxidative stress doc

Báo cáo khoa học: Cotton GhMPK2 is involved in multiple signaling pathways and mediates defense responses to pathogen infection and oxidative stress doc

... species scavenging capability and oxidative stress tolerance. These results increased our understanding of the role of the group C GhMPK2 gene in multiple defense-signaling pathways,including ... signalingprocesses and have unique biological functions.Cotton (Gossypium hirsutum) is one of the oldest and most important fiber and oil crops. Its growth and yield are severely inhibited under various biotic ... of the biologi-ABFig. 6. Analysis of ROS accumulation in wild-type and transgenicplants in response to abiotic and abiotic stresses. (A) Virus infec-tion-induced H2O2accumulation detected...
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Báo cáo khoa học: C fi G base mutations in the CArG box of c-fos serum response element alter its bending flexibility Consequences for core-SRF recognition potx

Báo cáo khoa học: C fi G base mutations in the CArG box of c-fos serum response element alter its bending flexibility Consequences for core-SRF recognition potx

... provide information on the localrepartition of the angles involved in the SREfoshelixbending.Relative effect of bending strainThere are several indications of a redistribution of the strains ... 25 °C, the higher entropy of the linearform is likely due to its higher flexibility, the highermobility of the hydration shell, or both. In the curved conformation, the strain exerted on the secon-dary ... take the effects of the thermal fluctuations by a higher frequency of helixtwisting [56]. The double mutation brings a higherrigidity and instability of the bent form, correlated to the higher...
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Báo cáo khoa học: Rice cytosine DNA methyltransferases – gene expression profiling during reproductive development and abiotic stress pptx

Báo cáo khoa học: Rice cytosine DNA methyltransferases – gene expression profiling during reproductive development and abiotic stress pptx

... showed similarity with the expression of AtCMT3 in young actively dividing tissues of roots and during the formation of inflorescence and floralmeristems and the initiation of floral organs (P1 -I and P1-II ... dur-ing the transition of plants from the vegetative to the reproductive phase has provided weighted insight into the developmental timing of the activity of these genes. The specific activation of ... maximumaccumulation in the SAM and early stages of panicleinitiation (P1 -I, P1-II and P1-III) and thereafter theirlevels declined in mature organs and during seed forma-tion. Transcripts for OsMET1-2,...
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Báo cáo khoa học: Endoplasmic reticulum stress caused by aggregate-prone proteins containing homopolymeric amino acids doc

Báo cáo khoa học: Endoplasmic reticulum stress caused by aggregate-prone proteins containing homopolymeric amino acids doc

... The accumulation of polyubiquitinated proteinwas also detected by western blotting withanti-ubiquitin antibody. (C) The accumulation of polyubiquitinated protein in the cytoplasm of homopolymeric Ile-expressing ... to their hydrophobic-ity. In the present study, we investigated the cytotoxicity of these aggre-gate-prone hydrophobic HPAAs, assuming that the ubiquitin proteasomesystem is impaired in the ... proteins invariably induceexcessive ER stress. In the context of disease, manystudies have shown the apparent toxicity of proteinaggregates in cell and animal models, but the specific-ity of the...
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Tài liệu Báo cáo khoa học: Transient RNA–protein interactions in RNA folding docx

Tài liệu Báo cáo khoa học: Transient RNA–protein interactions in RNA folding docx

... in either the replacement of the original strand or the expulsion of the invadingstrand, according to the kinetics and thermodynamicsituation. If the RNA chaperone also has annealingactivity, ... strand (Fig. 1C). A thirdstrand can utilize such destabilized regions as startingpoints for invasion. The concerted process of opening of the initial double strand and the annealing of the new ... chaperone–RNA interactionsis not a coincidence, but is in fact a prerequisite for the chaperone and annealing activity, and that it is the key to understanding the mechanism of protein-facilitated...
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Tài liệu Báo cáo khoa học: Diol dehydratase-reactivating factor is a reactivase – evidence for multiple turnovers and subunit swapping with diol dehydratase pdf

Tài liệu Báo cáo khoa học: Diol dehydratase-reactivating factor is a reactivase – evidence for multiple turnovers and subunit swapping with diol dehydratase pdf

... [17].Nucleotide and divalent cation specificities of the reactivase The specificities of the reactivase for nucleotides in the activation of the enzymeÆCN-Cbl complex were studiedin the presence of AdoCbl ... Positions of DD and its subun-its (aD, bD and cD) and the reactivase (DD-R) and its subunits (aR and bR) are indicated on the right of the gels. In (C), to improve visi-bility of the bands of ... specificity for nucleoside triphosphates in the activation of the enzymeÆcyanocobalamin complex. This result is consistentwith the lack of specific interaction with the adenine ring of ADP in the crystal...
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