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Báo cáo khoa học: Repeats of LacdiNAc and fucosylated LacdiNAc on N-glycans of the human parasite Schistosoma mansoni doc

Báo cáo khoa học: Repeats of LacdiNAc and fucosylated LacdiNAc on N-glycans of the human parasite Schistosoma mansoni doc

Báo cáo khoa học: Repeats of LacdiNAc and fucosylated LacdiNAc on N-glycans of the human parasite Schistosoma mansoni doc

... S. mansoni N-glycans with dimeric LacdiNAc FEBS Journal 273 (2006) 347–361 ª 2005 The Authors Journal compilation ª 2005 FEBS 361 Repeats of LacdiNAc and fucosylated LacdiNAc on N-glycans of the ... including the human parasite Schistosoma mansoni [2]. Glycans with LDN and LDNF {GalNAc(b1–4)[Fuc(a1–3)]GlcNAc(b1-}expressed by S. mansoni are targets of the humoralimmune responses of the host ... found on N-glycans from totalS. mansoni worm glycoproteins [2–5,24], O-glycans of the circulating cathodic antigen of S. mansoni worms[2–5,25] as well as on glycoproteins and glycolipids of granulocytes...
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Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc

Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc

... con-centration [44]. The dependences of the period of oscillations on the RPTP and Csk concentrationsalmost mirror each other, although there are quantita-tive differences in the changes of the period ... thatmirror stimulation or changes in the external condi-tions.We consider the time scale on which the total Srcconcentration (Stot) is conserved. Neglecting the con-centrations of dimers, S Á ... Dependence of the oscillation amplitude (A) and period(B) on the active RPTP concentration at constant Csk concentration(25 nM). The amplitude is the difference between maximal (s1max) and minimal...
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Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx

Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx

... 4¢-phosphopantothenicacid, CTP and cysteine. The synthesis of PPC occurs in two half reactions starting with the formation of 4¢-phosphopantothenoyl-CMP (activation of the carboxyl group of 4¢-phosphopantothenate). ... 6); the G-A transition concurs with the use of hydroxylamine as the mutagenic agent [14]. Therefore, the dfp-1 mutation is within the AAVAD motif of the C-terminal PPC synthetase (CoaB) domain of ... of D-pantothenate results in higher concentrations of 4¢-phos-phopantothenate and that the partial blocking of the Dfp(CoaBC) enzyme is overcome in this way. The molecular basis for the conditional...
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Báo cáo khoa học: Amino acid biosynthesis and metabolic flux profiling of Pichia pastoris ppt

Báo cáo khoa học: Amino acid biosynthesis and metabolic flux profiling of Pichia pastoris ppt

... 2004Cb (Table 2). These reveal the reversible activity of the transketolase and transaldolase reactions when P. pastorisis grown on glycerol. On the other hand, the wealth of information obtained ... for the duration of one volume change with the mediumcontaining the 13C-labeled substrate [16,18] before harvest-ing the biomass. Then, the fraction of unlabeled biomassproduced prior to the ... carbon source. Hence, the comparison of flux ratios at this dilution rate allows one toassess the impact of the different chemical nature of the twomolecules (Fig. 1) on metabolic regulation...
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Báo cáo khoa học: Crosstalk between Src and major vault protein in epidermal growth factor-dependent cell signalling docx

Báo cáo khoa học: Crosstalk between Src and major vault protein in epidermal growth factor-dependent cell signalling docx

... MVP, which may regulate the interaction of Src and MVP. With all the uncertainty and lack of infor-mation, we strongly believe that elucidation of the interplays between Src and MVP can be very ... elu-cidation of the physiological function of the PTEN–MVP interaction and effects on PTEN activity mayshed new light on the role of MVP in cells. In a morerecent study, SH2 domain-containing ... correlation exists between the suppression of Src activities by MVP and suppression of Src-mediated ERK activation upon EGF stimula-tion. Thus it is tempting to suggest that the two arelinked, and...
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Báo cáo khoa học: Super life – how and why ‘cell selection’ leads to the fastest-growing eukaryote doc

Báo cáo khoa học: Super life – how and why ‘cell selection’ leads to the fastest-growing eukaryote doc

... biomass synthesized. The rate of growth is independent of BCR and DpH, and depends only on the conditions under which the micro-organism is cultured and the properties of the Control of highest ... (BCR,defined as the amount of acid or base required tochange the pH of 1 L of the medium in the reservoirto the pH of the medium in the culture vessel [56]),provided that a constant number of protons ... environ-mental conditions at constant pH, temperature and biomass concentrations [1,56]. The rate of growth wasindependent of the buffer capacity of the inflowing freshmedium and the pH difference...
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Báo cáo khoa học: Apo a-lactalbumin and lysozyme are colocalized in their subsequently formed spherical supramolecular assembly doc

Báo cáo khoa học: Apo a-lactalbumin and lysozyme are colocalized in their subsequently formed spherical supramolecular assembly doc

... spectral modefor the acquisition of the spectra of the dyes. For the acqui-sition of images using the standard mode, FITC and RBITCwere excited at 488 and 543 nm, respectively, and the emit-ted ... similar, with the visualization of the same spheres in the same area of the image. Further-more, the size of the spheres observed with FITC(Fig. 4A) was identical to the size of the spheresobserved ... nat-ure and energy of the interactions) leading to differentsupramolecular structures [3], and for the control and orientation of protein interactions and cluster forma-tion. We are convinced...
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Báo cáo khoa học: Structural evidence for a constant c11 ring stoichiometry in the sodium F-ATP synthase doc

Báo cáo khoa học: Structural evidence for a constant c11 ring stoichiometry in the sodium F-ATP synthase doc

... ringpreparations suggests that the insertion of the last csubunit forms the limiting step in the assembly process of a functional oligomer.Upon closer inspection, the occurrence of additionalprotrusions ... the recombinant T67C mutant, with the exception of anadditional band corresponding to (c11)2 and aggregatesat the top of the gel. For comparison, the c11ring pre-paration of wild-type I. tartaricus ... expression levelor the nutritional status of the cells [15].Knowledge on the aggregation behavior of the c ringhas been of considerable value in exploring suitablecrystallization conditions for structure...
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Báo cáo khoa học:

Báo cáo khoa học: "From Submit to Submitted via Submission: On Lexical Rules in Large-Scale Lexicon Acquisition" docx

... checking of the results of the application of LRs to the basic entries, such as those for the verbs. The shifts and modulations studied in the litera- ture in connection with the LRs and generative ... possibly updated. • Itule LIIS Constraints - The other approach is to maintain a bank of LRs, and rely on their LHSs to constrairi the application of the rules to only the appropriate cases; in ... is their promise to aid the task of massive lexical acqui- sition. Section 2 below outlines the nature of LRs in our approach and their status in the computational pro- cess. Section 3...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

... otherenzymes in neurons. Alternatively, the inhibition of neuronal long-chain fatty acid oxidation could contrib-ute to body weight control. The roles of long-chainfatty acyl-CoAs and long-chain fatty ... physiological conditions? Because glucose is the primary fuel for the CNS and blood glucose and hypothalamic malonyl-CoA levels fall and rise togetherduring food deprivation and refeeding, it was reasonedthat ... entry of fatty acid into mitochon-dria. Thus, the steady-state level of malonyl-CoA inthese tissues is determined by the relative activities of ACC and malonyl-CoA decarboxylase.Role of the...
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