Báo cáo khoa học: Bridging the gap between in silico and cell-based analysis of the nuclear factor-jB signaling pathway by in vitro studies of IKK2 ppt
... proliferation and collagen synthesis
involve the b-catenin signaling pathway.
Inhibition of b-catenin signaling pathway using
quercetin blocked the a-defensin-induced
increase in collagen release ... signaling pathway. We then studied the role
of the b-catenin signaling pathway in a-defensin-
induced increases in the proliferation and collagen syn-
thesi...
... categories of the words in the sentence and dis-
play the information they contain. Figure 2 and 3
show, respectively, several annotation levels of the
sentences in the example and the constituency ... using the Jaccard coefficient. First,
the sets of all lexical items that are found in the ref-
erence and the candidate sentences are considered.
Then, O...
... present the first provably
efficient algorithm to enumerate the read-
ings of MRS structures, by translating
them into normal dominance constraints.
1 Introduction
In the past few years there has ... are
connected by a hypernormal path in the graph of the
restricted constraint Φ
|V−{X
1
}
, and there exists no Z
such that X
∗
Z in Φ.
The requirement of hypernorma...
... sit-
uated in a solution of the solved form. They can
either dominate each other in either direction, or
they can be
disjoint.
But if they are disjoint, we
also know the lowest node that dominates them
both, ... holes in all connecting
chains in
y
o
.
Then the constraint
y
o
A • A (p
0
is
chain-connected.
2
The original grammar accounts for scope island con-
straints...
... FEBS
Bridging the gap between in silico and cell-based analysis
of the nuclear factor-jB signaling pathway by in vitro
studies of IKK2
Adaoha E. C. Ihekwaba
1,4
, Stephen J. Wilkinson
1
, Dominic ... absence of the SC-514 inhibitor. (D, E) Time
course plot of nuclear NF-jB from in vitro and in silico analysis of the data. The...
... (EMSA) and R dRp
assays, and examined the in uence of d ifferent cis-acting
elements on binding of NS5B protein and RNA synthesis
in vitro.
Materials and methods
Expression and purification of NS5B ... to
binding of the CSFV NS5B protein. The minus-strand
3¢ UTR with deletion of the 21 nucleotide fragment at the
terminal did not interact with the N S5B prot...
... could
participate in proton translocation or, in the case of
E103, in the binding of the twin-arginine motif in the
signal peptide. The absence of any translocation
defects leads us to conclude that these ... 2275
Evidence for interactions between domains of TatA
and TatB from mutagenesis of the TatABC subunits
of the twin-arginine translocase
Claire M. L...
... removal of which shifts the ratio between the strength (indica-
ted by the thickness of the curved arrows) of the cis and trans
interactions in favor of the latter. An increase in the trans inter-
action ... pairing between these sequences within
the BX-C plays a role in restricting the extent of loop-
ing-out domains.
Tethering elements
Deletion ana...
... representation is defined as a
mapping between elements of the set of substrings
of the string and elements of the set of subtrees
of the tree : such a relation is called a string-
tree correspondence. ... string
of terms, and finally the correspondence which is
a mapping (given by the arrows ~ ~>) defined
between substrings of STRING and subtrees...
... enzyme
The activity of the enzyme present in the crude extract of
strain 10d that used 2 -amino-5-carboxymuconic 6-semi-
aldehyde as substrate was measured by monitoring the
increase in the absorbance ... of the purified enzyme at 266 nm. The typical
protein absorption p eak of 2 80 nm shifts to 265 nm if the
protein contains a flavin-type cofac tor [28]. We faile...