... article.
Modulating amyloid-b aggregation M. Nitz et al.
1674 FEBS Journal 275 (2008) 1663–1674 ª 2008 The Authors Journal compilation ª 2008 FEBS
Modulation of amyloid-b aggregation and toxicity
by inosose stereoisomers
Mark ... identified inositol stereoisomers as exhibiting stereospecific
inhibition of A b aggregation and toxicity in vitro and in vivo. We re...
... mediated by the ANT in maximally
polarized (forward mode of both ANT and ATPase)
and maximally depolarized (reverse mode of both
ANT and ATPase) mitochondria.
Flux control coefficients of ANT and F
0
F
1
-ATP
synthase ... difference of DWm (termed
Delta phi) before and after the addition of ADP
(2 mm) to WT and CYPD KO mitochondria, and cal-
culated on the basis of...
... action of EPA and DHA (Eur. J. Biochem. 271) 4465
Modulation of cyclin D1 synthesis and
hyperphosphorylation of Rb by n-3 and n-6 PUFAs
Induction of cyclin D1 is one of the e arliest effects of
mitogenic ... Anti-mitogenic action of EPA and DHA (Eur. J. Biochem. 271) 4473
Modulation of cyclin D1 and early growth response factor-1 gene
expression in interleukin-...
... 3).
Modulation of the interaction of AhR-LBD with
CBP by AhR ligands
AhR activation is at least partially mediated by the
recruitment of CBP to the target promoters [29]. To
assess the influence of ... receptor:
implications for prevention of dioxin toxicity. Mol Phar-
macol 56, 784–790.
51 Edwards DP (2000) The role of coactivators and core-
pressors in the biology and...
... Ricerche, Genova, Italy
3 Heisenberg Group of Biophysics and Molecular Plant Biology, Institute for Biochemistry and Biology, University of Potsdam, Potsdam-
Golm, Germany
Introduction
Plants ... (nPKC; d, h, g and e), which lack
Ca
2+
-binding sites, and atypical PKCs (aPKC; f, k ⁄ i
and l), which are Ca
2+
-insensitive and are not acti-
vated by phorbol esters [37]. Both c...
... Modulation of Ca
2+
entry by TRPM4b
FEBS Journal 274 (2007) 704–713 ª 2006 The Authors Journal compilation ª 2006 FEBS 713
Modulation of Ca
2+
entry and plasma membrane potential
by human TRPM4b
Ralf ... indicated by arrow; solid lines) or untreated
(dashed lines). (B) Quantitative analysis of the amplitude of Ca
2+
released by ionomycin (left) and the amplitude of C...
... solu-
tion of ThT and the fluorescence intensity of the solu-
tion was measured at 482 nm. Figure 4A shows the
kinetics of aggregation of a-synuclein in the presence
of 100 lm MPTP and the effect of 50 ... rate of a-synuclein aggregation even in the absence of com-
ponents of mitochondrial complex I. In contrast to the effect of dopamine
on the aggregation of a-...
... system of shuttle vec-
tors and yeast host strains designed for efficient manip-
ulation of DNA in Saccharomyces cerevisiae. Genetics
122, 19–27.
Sterol homeostasis modulation by Ste20p and Cla4p ... Deletion of CLA4 results in higher amounts of SE. (A) Quan-
tification of SE in cell polarity mutants. Cells of the indicated strains
were grown to stationary phase and then l...
... arrangement.
Design and construction of C266, G267 and L268
single and double FNR mutants
Five single mutants of C266, G267 and L268 and a
double mutant of C266 and L268 were successfully
constructed and confirmed ... Role of methionine
56 in the control of the oxidation–reduction potentials
of the Clostridium beijerinckii flavodoxin: effects of
substitutions by al...
... digestion of the DNA samples.
On the other hand, the absence of a second hybridiza-
tion band in lane 1 might be the result of insufficient
sensitivity of our assay. Rehybridization of the mem-
brane ... the
time-course modulation of foreign gene expression
and to investigate whether this modulation can be
explained by the concomitant changes occurring in the
parasite genom...