Báo cáo khoa học: The effect of heme on the conformational stability of micro-myoglobin doc

Báo cáo khoa học: Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase pdf

... Val position in order to verify the inﬂuence of the nature of the amino acid at this position on determination of the cleavage sites and on the amount of their hydrolysis. This series of peptides ... [3]; and from the deconvolution of CD at 37 °C in the absence of NaCl (195–260 nm) was 51%. For the spectrum of TOP in the sameconditions the deconvolution indicated 45% of a helixcontent. This ... TDSÃð3ÞDependence of the hydrolysis reaction ratesby neurolysisn and TOP on concentration and chemicalnature of salts The dependence of the rate constants according to the concentration and the chemical...

Tài liệu Báo cáo khoa học: "Organizing Encyclopedic Knowledge based on the Web and its Application to Question Answering" ppt

... to the description.For the second type of question, human examineeswould search their knowledge base for the description of each of four candidate terms. Then they wouldchoose the candidate ... Examinations The Class II examination consists of quadruple-choicequestions, among which technical term questions canbe subdivided into two types.In the ﬁrst type of question, examinees choose the ... foundthat each of the TREC questions can be recast as ei-ther a single axis or a combination of axes. They alsofound that out of the 200 TREC questions, 64 ques-tions (approximately one third)...

Báo cáo khoa học: "SOLUTIONS TO ISSUES DEPEND ON THE KNOWLEDGE REPRESENTATION" ppt

... b,~se, the h~ndling o? time is rrither strriightforwrird, However this c~se of& quot;~en does not ripply, Consider the ?allowing e xQmp], e. : " ;The Ki~tyhriwk ~rrived in London Monday, The ... in London together sriil together?" One rins~er would be: " ;The Ki~i'.vh~.~wk rirrived IriF~t Mondc~y~ the Mor, u will soil next Friday, I~ they will hrive b~.en there ... will hrive b~.en there qt the same ~iMe~ then not rill ships ~hr~t were in London together will sriil 1'ogether~ bu~ they v:ould be the only exceptions," Choosing ~ relev~mt...

Báo cáo khoa học: "Automatic Text Summarization Based on the Global " ppt

... browsing these texts. The browser has the functionality of summarization and content-based retrieval of tagged documents. This paper focuses on summarization based on this system. The main ... or One of them is the syntactic head of the other. 2. The unmarked element with the highest activation value is marked for inclusion in the sum- mary. 3. When an element is marked, other ... elements in the intra-docmnent net- work are generated preserving the order of their positions in the original document. 5. If a size of the sunnnary reaches the user- specified value, then ternfinate;...

Báo cáo khoa học: "AN INTERNATIONAL DELPHI POLL ON FUTURE TRENDS IN "INFORMATION LINGUISTICS"" doc

... Standardization of Information/Documentation Languages il6 Documentation Languages for Non-Textual Data il7 Information/Documentation Languages for Heterogeneous Domains lib Determination of Linguistic ... practitioners, on advices from members of FID/LD, and on long discussions with Don Walker, Hans Karlgren, and Udo Hahn. Altogether, there were 91 topics in the first round and 90 in the second ... point of view looks different from an application one. The values in the second round are in general higher than in the first one. This is an argument against the oft cited Delphi hypothesis...

Báo cáo khoa học: Small exterior hydrophobic cluster contributes to conformational stability and steroid binding in ketosteroid isomerase from Pseudomonas putida biotype B pot

... steroids rather than the binding itself.In conclusion, the mutational studies on the role of the SEHC in KSI-PI demonstrate that the SEHC con-tributes not only to conformational stability, ... kH2OUis the unfolding rate constant in the absence of urea and mUà the dependence of the unfolding rate con-stant on urea concentration. The free energy of activationfor the unfolding of KSI-PI ... extrapolation of the data to a concentration of 0 M urea during denaturation.bm is the slope of the linear dena-turation plot, dDGU⁄ d[urea].c[Urea]50%is the concentration of urea at...

Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

... posi-tioned in the connecting loops. Approximately one-third of all mutations in the BTK gene are missenseand some of these reduce the stability of the protein.This is exempliﬁed by mutations ... substitution of the corresponding R25 in the pleckstrin homology(PH) domain also results in loss of function [16,17],thereby demonstrating related functions amongselected PH domains. Thus, from the ... the effect of proteasome inhibitors on HIV infection and ⁄ or replica-tion. To determine whether the depletion of ITK couldaffect HIV replication, we treated activated periph-eral blood mononuclear...

Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc

... assessment of the trajec-tory of interconversion rates as a function of time of cold exposure, (b) comparison of the magnitudes of the various interconversion rates, and (c) lineup of the accessions ... activity of the catalysingenzyme (Vmax,A) and the enzyme speciﬁc substrate afﬁnity,expressed by Km,A. It also depends on the concentration of the reaction product and the dissociation constant ... correlation of sucrose synthesisand degradation with the process of cold acclimation.We conclude that acclimation to low temperature rep-resents a dynamic process, the investigation of whichtherefore...

Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc

... modu-lation of Ca2+oscillations by increasing agonist con-centration [44]. The dependences of the period of oscillations on the RPTP and Csk concentrationsalmost mirror each other, although there ... thatmirror stimulation or changes in the external condi-tions.We consider the time scale on which the total Srcconcentration (Stot) is conserved. Neglecting the con-centrations of dimers, S Á ... QSS curve on each kineticparameter involved.Fig. S4. Effects of saturabilities of reaction rates on the QSS dependencies.Fig. S5. Effects of large concentrations of Src dimers on the QSS dependence.Table...

Tài liệu Báo cáo khoa học: A facile method for expression and puriﬁcation of the Alzheimer’s disease-associated amyloid b-peptide pdf

... preventdegradation. A common drawback of such approachesis the cost of the afﬁnity resins used to isolate the fusion protein and the proteases required to liberate the protein of interest from the fusion ... using the devices and loss of peptide on the column resin. The only detriment of the peptidesproduced here is the fact that they contain an exo-genous N-terminal methionine. However, the presence of ... absorption of tyrosine at 275 nm(e275= 1400 m)1Æcm)1) was used to estimate the concentration of Ab in solution. In four separate puri-ﬁcation experiments, the concentration of Ab(M1–40)in the...

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