... RC -10 1 [14 ]. Ofthe three mutations, one was found in gp120 and oneeach in the HR1 and HR2 regions of gp 41, and allthree mutations converted a polar or anionic residue toa cationic residue [14 ]. ... residues suggest an attempt by the virus to repel the cationic lectin, RC -10 1 [14 ,17 ].As all nonsynonymous mutations in RC -10 1-exposed HIV -1 were cationic mutations [14 ], andbecause HR2 is the principal ... RC -10 1 overcomes cationic mutations in HIV -1 gp 41 FEBS Journal 274 (2007) 6477–6487 ª 2007 The Authors Journal compilation ª 2007 FEBS 6487Retrocyclin RC -10 1 overcomes cationic mutations on...