... clinical experience with dronabinol.Pharmacol Biochem Behav 1991;40:695-700.124. Di Marzo V, Goparaju SK, Wang L, et al.Leptin-regulated endocannabinoids are involved in maintaining food intake. ... 73CA Cancer J Clin 2002;52:72-91routinely used, this method can provide datathat is helpful in evaluating investigationaltreatments and, in the future, may becomemore important in clinical ... participating in the response remain to be determined. Serotonin may also play a role in the development of cancer anorexia. Increased levels of plasma and brain tryptophan, the precursor of serotonin,...