Báo cáo khoa học: Re-evaluation of the function of the F420dehydrogenase in electron transport ofMethanosarcina mazei potx

Báo cáo khoa học: Re-evaluation of the function of the F420dehydrogenase in electron transport ofMethanosarcina mazei potx

Báo cáo khoa học: Re-evaluation of the function of the F420dehydrogenase in electron transport ofMethanosarcina mazei potx

... absent in the cyto- plasmic fraction of the DfpoF mutant. This observation prompted investigation into the function of FpoF in more detail. The corresponding gene, mm0627, was expressed in E. ... in favour of this hypothesis came from the finding that the rate of F 420 H 2 -depen- dent heterodisulfide reduction in cell lysates of the DfpoA-O mutant or the D...
Ngày tải lên : 14/03/2014, 23:20
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Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt

Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt

... contained a 30 bp insertion in the ORF, beginning at nucleotide 516. This resulted in insertion of a 10 amino acid segment (TREIDYPETI) and one substitution (Ser fi Gly) at the C-terminal end of the ... ortho- log of the product of this gene. In the clade including Spa ¨ tzle-1, the branch lengths are noticeably longer and the bootstrap values are lower than in t...
Ngày tải lên : 06/03/2014, 09:22
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Báo cáo khóa học: Selective release and function of one of the two FMN groups in the cytoplasmic NAD + -reducing [NiFe]-hydrogenase from Ralstonia eutropha pptx

Báo cáo khóa học: Selective release and function of one of the two FMN groups in the cytoplasmic NAD + -reducing [NiFe]-hydrogenase from Ralstonia eutropha pptx

... The protein part that holds two of the Fe-S clusters in the small subunit of the D. gigas enzyme is missing in HoxY of the SH, suggesting an exposure of part of the hydrophobic surface of the HoxH ... changes of the Ni-Fe site. The Fe-S clusters in the HoxFUY subunits and the flavin in the HoxF subunit are all considered to be functional in the...
Ngày tải lên : 07/03/2014, 15:20
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc

Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc

... argues against a role for a3inthe formation of native MII binding sites, but may reflect the scarcity of these sites in the investigated brain tissues and/or the formation of low affinity binding sites ... microdomains within the same binding site [35]. The proline residue in position 6, which is conserved in all other a-conotoxins, appears to be the major determinant o...
Ngày tải lên : 19/02/2014, 12:20
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Báo cáo khoa học: Studies on structure–function relationships of indolepyruvate decarboxylase from Enterobacter cloacae, a key enzyme of the indole acetic acid pathway ppt

Báo cáo khoa học: Studies on structure–function relationships of indolepyruvate decarboxylase from Enterobacter cloacae, a key enzyme of the indole acetic acid pathway ppt

... tripalmitin as standards. The scattering patterns were collected in 15 frames of 1 min to verify the absence of radiation damage. The experimental data was normalized to the intensity of the incident ... enol form of indolepyruvate (Fig. 1). In the course of the establishment of the equilibrium % 85% of the enol form is converted into the ketone (half-tim...
Ngày tải lên : 08/03/2014, 02:20
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Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc

Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc

... successful metabolic engineering of freezing tolerance in plants should include such an analysis of the dynamics of metabolism to gain com- prehensive information about the effects of individual overexpression ... simulta- nous reduction in hexose concentration, particularly during the initial period of cold exposure. Using RNA interference-mediated inhibition of the d...
Ngày tải lên : 14/02/2014, 22:20
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Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx

Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx

... N7 (Fig. 1C). The 2¢OH of the ribose is hydro- gen bonded to the main chain and the side chain of Asp142 (Fig. 1C). Both hydroxyl groups of the ribose are involved in coordinating a putative ... solutions. The ligand bound was interpreted as GMP because the N2 of the base makes a hydrogen bond to a main chain car- bonyl. Binding of a xanthine base from XMP in th...
Ngày tải lên : 15/02/2014, 01:20
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Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx

Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx

... all-alpha domain, STAT protein DNA-binding domain and SH2 domain of stat6, and the zinc-finger domain, leucine-zipper domain and fork-head domain of foxp3. In addition, for stat6 and foxp3, there were ... adjacent DNA-binding sites, a coiled-coil STAT protein all-alpha domain, which is implicated in other protein–protein interactions, a STAT protein DNA-binding domain and an SH2 doma...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion pptx

Tài liệu Báo cáo khoa học: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion pptx

... strains [3]. Pathogenic Yersiniae are typically taken up through ingestion and first reach the intestine. The Yersinia surface protein invasin binds to b1 integrins on the apical surface of M ... In addition to actin, other host cell proteins have been shown to bind to the virulence factor YpkA, including OTUB1 [13]. In order to investigate the role of OTUB1 in Yersinia inv...
Ngày tải lên : 16/02/2014, 15:20
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Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx

Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx

... number of these modifications is low, the density of modifications is much the same as in the rest of the lin- ker histones. It is the shortness of the N-terminal tails Table 1. Alignment of chicken, ... the triphosphate form being incorpo- rated into DNA in place of the natural base cytosine [12]. The use of such analogues results in the global depletion...
Ngày tải lên : 18/02/2014, 08:20
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