... micro-domains contain, among others, a potential regulatoryprotein of T c ell growth, CD48. A pivotal role of cholesterol in maintaining such t ransient protein assemblies, includingalso HLA ... of the interleu kin-2 receptor complex(IL-2R) are involved in both proliferative and activation-induced cell death ( AICD) s ignaling o f T cells. In addition,the s ignaling b and c chains are ... Sugamura, K. &Waldmann, T.A. (1994) Cooperative interactions between theinterleukin 2 receptor alpha and beta chains alter the interleukin2-binding affinity o f the receptor subu nits. Proc. Natl...