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Báo cáo Y học: Kinetic and biochemical analyses on the reaction mechanism of a bacterial ATP-citrate lyase ppt

Báo cáo Y học: Kinetic and biochemical analyses on the reaction mechanism of a bacterial ATP-citrate lyase ppt

Báo cáo Y học: Kinetic and biochemical analyses on the reaction mechanism of a bacterial ATP-citrate lyase ppt

... Kinetic and biochemical analyses on the reaction mechanism of a bacterial ATP-citrate lyase Tadayoshi Kanao, Toshiaki Fukui, Haruyuki Atomi and Tadayuki ImanakaDepartment of Synthetic ... account the reaction mechanism of mammalian ACL [23], the final step of the reaction can be assumed to be the nucleophilic attack of CoA to the phosphorylated carbonyl carbon of citrylphosphate, and ... play a vital role in providing acetyl-CoA and oxaloacetate in the cytosol as starting materials for a variety of biosynthetic pathways. Rat and human ACLs fromvarious organs and tissues have...
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Báo cáo y học:

Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"

... its translocation to the cytoplasm and nucleus and that the subcellular localization of claudin-1 may dictate the metastatic capacity of melanoma cells. Our findings suggest that nuclear versus ... F:5'-ttcctgtccccgaaaaacagactcttacccaacaccaagg-3' R:5'-ccttggtgttgggtaagagtctgtttttcggggacaggaa-3' 189-192 KTTS KXX[pS/pT] PKA A5 68G_C56 9A_ A570C_ A5 71G_C57 2A F:5'-actttgctgttcctgtccccgaaaagacgactcttacccaacaccaaggccc-3' ... PKA A5 71G F:5'-gctgttcctgtccccgaaaaacagcctcttacccaa-3' R:5'-ttgggtaagaggctgtttttcggggacaggaacagc-3' 189-192 KTTS* KXX[pS/pT] PKA A5 68T _A5 71G F:5'-ctgttcctgtccccgaaaatcagcctcttacccaacac-3'...
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Tài liệu Báo cáo Y học: Structural and biochemical characterization of neuronal calretinin domain I– II (residues 1– 100) Comparison to homologous calbindin D28k domain I–II (residues 1 –93) pdf

Tài liệu Báo cáo Y học: Structural and biochemical characterization of neuronal calretinin domain I– II (residues 1– 100) Comparison to homologous calbindin D28k domain I–II (residues 1 –93) pdf

... C.P.(1999) A kinetic and stereochemical investigation of the role of lysine-32 in the phenylpyruvate tautomerase activity catalyzed bymacrophage migration inhibitory factor. Biochemistry 38,16024–16033.44. ... critical evaluation of the manuscript and Barbara Zarzycka (Warsaw) for her technical assistance. This work wassupported by an International Center for Genetic Engineering and Biotechnology (ICGEB) ... data of A ˚kerfeldt et al. [29] agreeswith the large body of independent data collected on Calb and truncated Calbs by Kumar’s group. This latter workrevealed that EF-hands II and VI of Calb...
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Báo cáo Y học: Structural and biochemical characterization of calhepatin, an S100-like calcium-binding protein from the liver of lungfish (Lepidosiren paradoxa) docx

Báo cáo Y học: Structural and biochemical characterization of calhepatin, an S100-like calcium-binding protein from the liver of lungfish (Lepidosiren paradoxa) docx

... showing an aberrant mobility, in the same wayas other CaBPs [10,18–20]. The molecular mass as deter-mined by MALDI-TOF MS is 8672 Da.Analysis of the apo-calhepatin, at 7 lMmonomerconcentration, ... trifluoroacetic acid] over 80 min.Amino-acid analysis and sequencingPeptide amino-acid analyses and automatic amino-acidsequence determination by Edman degradation were carriedout in an Applied ... where the Ca2+concen-tration reaches a relatively high level [3]. Additional modes of affinity control may involve other factors such as othercations. The affinity of S100 proteins for Ca2+can...
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Báo cáo y học:

Báo cáo y học: "Surgical and medical emergencies on board European aircraft: a retrospective study of 10189 cases"

... European Joint AviationAuthorities (JAA; Cologne, Germany) regulate aviation on the national and continental level. They regulate by law the con-tents of an on- board dispensary and the MFK. However, ... whichincluded the frequency and type of emergency. The frequency of aircraft diversion was also investigated. All data regardingnames, ages and the sex of the patient and the name of the air-line were anonymous. ... in a variety of different med-ications and equipment on board. In Germany, the regulations of the National Federal Aviation Agency (Luftfahrt-Bundesamt,Braunschweig, Germany) and the European...
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Tài liệu Báo cáo khoa học: Molecular and biochemical characterization ofD-phosphoglycerate dehydrogenase fromEntamoeba histolytica A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways docx

Tài liệu Báo cáo khoa học: Molecular and biochemical characterization ofD-phosphoglycerate dehydrogenase fromEntamoeba histolytica A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways docx

... Nozaki, T.(2003) Identification and characterization of two isoenzymes of methionine c -lyase from Entamoeba histolytica: a key enzyme of sulfur-amino acid degradation in an anaerobic parasitic ... respectively [14]. These dataindicate, by analogy, that serine biosynthesis may also beregulated to maintain the intracellular cysteine concentra-tion in the amoeba. Modulation of expression of PGDH and ... PGDH and other enzymes involved in the phosphorylated pathwayby cultivation of the amoebic trophozoites with a variety of amino acids is underway.It was previously shown that dimerization and...
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Báo cáo khoa học: Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis pptx

Báo cáo khoa học: Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis pptx

... interactions of the carbonyl oxygen atoms of the pyrimidine ring and the protein chain. Namely, there are two new directhydrogen bonds formed between carbonyl oxygen O1 and the main chain Ala59N and ... oxygen atoms of Ala59 and Glu61 of one subunit and with the main chain nitro-gen of Asn114¢ of the other subunit. The contacts of the ribityl chain to His89 and Lys138¢ are mediated by a net of ... furthermore,NHNHNH2HNOONONNNHONHNO ON NOPO3OOHPO4OHOHOHOHOHOHOHOHOHOHOHOH3-Lumazine SynthaseRiboflavin SynthaseGTP123+4Fig. 1. Terminal reactions catalyzed by luma-zine synthase and riboflavin synthase in the pathway of riboflavin biosynthesis. 1,5-Amino-6-ribitylamino-2,4(1H,3H)...
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Báo cáo y học:

Báo cáo y học: " Facilitators and obstacles in pre-hospital medical response to earthquakes: a qualitative study"

... Absence of transportation plan- Lack of standardized transportation system- No control on transportation of the casualties- Airlifting of casualties by ArmyDjalali et al. Scandinavian Journal of ... standardiza-tion or overall coordination and with a delayed start.They divided the airport waiting rooms into a few sepa-rate areas. They evaluated most of the casualties beforefurther transport ... by vehicles. Additionally alltransportation from Bam to the airport and the furtherevacuation by air was stopped during the first nightbecause of darkness, very cold weather and lack of safety....
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Báo cáo y học:

Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"

... contributions All authors made substantial contributions to conception and design, and to the analysis and interpretation of the data. TRM and GWC handled acquisition of data. All authors contributed ... administrative claims data. By way of comparison, the Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis ... provide a preliminary mechanism to evaluate the effectiveness of RA medications in administrative claims and pharmacy data. While clinical disease activity measures remain the gold standard for assessing...
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Báo cáo y học:

Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"

... only after the second year of life [4,8,9]. By the age of 4 years, the average cranial extent of the frontal sinus reaches half the height of the orbit and extends just above the top of the ... Embryology, Development and Anatomy of the Nose, Paranasal Sinuses, Nasolacrimal Passageways and Ol-factory Organs in Man. Philadelphia: P Blakiston’s Son; 1920. 8. Som PM, cCurtin HD. Head and ... study evaluated the DVT images using DVT software (Quantitative Radi-ology, NNT Software version 2.21, Verona, Italy) with respect to aplasia and agenesis of the frontal sinus on coronal images...
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