Báo cáo khoa học: "Effects of Word Confusion Networks on Voice Search" pdf

... Proceedings of the 12th Conference of the European Chapter of the ACL, pages 238–245,Athens, Greece, 30 March – 3 April 2009.c2009 Association for Computational LinguisticsEffects of Word Confusion ... ﬁelds with par-ticular emphasis on exploiting the ASR output be-yond the 1-best hypothesis. We demonstrate thatby parsing word confusion networks, the accuracy of the query parser can be improved. ... number of reasons.First, as can be expected the ASR 1-best out-put is typically error-prone especially when a userquery originates from a noisy environment. How-ever, ASR word confusion networks...

Báo cáo khoa học: Effects of the antioxidant PycnogenolÒ on cellular redox systems in U1285 human lung carcinoma cells docx

... functions, including reduction of thioredoxin andother low molecular weight substances, and reductionand detoxiﬁcation of hydroperoxides [9]. This reductionmay be direct or by regeneration of ... here that regulation of TrxR appears to beprimarily dependent on the redox state of the cell,rather than the selenium content. This is demonstratedby the effect of addition of PycnogenolÒafter ... [24–26].The aim of this study was to investigate the antioxi-dant effects of PycnogenolÒ on redox enzymes, withemphasis on the regulation of TrxR.ResultsEffects of PycnogenolÒ on cellular TrxR...

Báo cáo khoa học: Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4 doc

... biological action of the peptide. Finally, the effect of the tryptophanyl substitution at position 16 on thebiological activity was conﬁrmed for the native GGN4.Consistent with the results of the C-terminally ... C-terminal part. The dis-ordered conformation in the C-terminal region of D24)37GGN4 is probably due to the break of the peptide bond atposition 23. In contrast, the ﬁnally selected structures(Fig. ... inan aqueous solution, but adopts a helical conformationconsisting of two amphipathic a helices (residues 2–10 and16–32) in membrane-mimetic environments. Recently, aspart of an effort to develop...

Tài liệu Báo cáo khoa học: Effects of sequestration on signal transduction cascades docx

... concentrationand total kinase concentration, respectively, and KMisthe Michaelis–Menten constant of the kinase. The con-centration of the complex [TK] approaches the totalconcentration of ... expressedthe response of the active fraction to a change of thekinase concentration as a function of the concentra-tions of the two forms ([T] and [T*]) and the elastici-ties of the enzymes ... of the kinase (G–I). (A) Contour plot of the responsecoefﬁcient RT ÃKTas function of the total concentration of the phosphatase and the kinase (normalized to the phosphatase concentration)....

Báo cáo khoa học: Effects of a novel arginine methyltransferase inhibitor on T-helper cell cytokine production pot

... identiﬁcation of one such com-pound and the characterization its inhibitory proper-ties, focusing on its modulation of Th cell function.ResultsChemistryIn the report disclosing the activity of AMI-1, ... methylation reactions of recombinant Set7 ⁄ 9 with calf thymushistones as substrate and [3H]SAM in the presence of increasing concentrations of AMI-1 or compound 4. Data are representative of at ... of increasing concentrations of AMI-1 or compound 4(Compd 4). (B) In vitro methylation reactions of recombinant GST–PRMT6 or GST–PRMT8 together with GST–GAR and [3H]SAM in the pres-ence of...

Báo cáo khoa học: Effects of thymoquinone on isolated and cellular proteasomes pot

... TQ concentrations of 5 and20 lm, whereas it decreases at a concentration of 100 lm (corresponding to the recovery of proteasomeactivity). At the same time, increases in TQ concentra-tion resulted ... mutation consists of a single G ﬁ A transi-tion in codon 237, resulting in a missense mutation of methionine to isoleucine [32,33]. Interestingly, a studyconducted by Van Meir et al. on different ... the hydrolyzed AMCwas detected on a SpectraMax Gemini XPS microplatereader.Detection of proteasome–quinone adductsDetection of the TQ-mediated formation of quinoneadducts in isolated 20S immunoproteasomes...

Báo cáo khoa học: Effects of the G376E and G157D mutations on the stability of yeast enolase – a model for human muscle enolase deﬁciency pdf

... position would result ina change in the conformation of this loop. Changes inthe conformation of the backbone at this point andchanges in the orientation of other side chains, as aresult of ... protein was dimeric under ourstandard conditions of 1 mgÆmL)1and 15 °C. Physio-logical conditions of ionic strength and temperaturepromoted the dissociation of both variants. This is notsurprising, ... of variants of yeast enolase and, inmany cases, the introduction of mutations hasdecreased the temperature stability. Although aFig. 6. Peptide bond CD of the monomeric and dimeric forms of wild-type...

Báo cáo khoa học: Effects of salt on the kinetics and thermodynamic stability of endonuclease I from Vibrio salmonicida and Vibrio cholerae potx

... the effect of NaCl concentration on the kinetic constants and thermodynamic stability of VsEndA and VcEndA was investigated. In addition,the effects of reciprocal mutations of two non-con-served ... stoichiome-tries of participation of water, cations and anions inspecific and non-specific binding of lac repressor toDNA. Possible thermodynamic origins of the ‘‘gluta-mate effect’’ on protein–DNA ... ithmeasurement of reflection h and <I(h)> is the weighted mean of allmeasurements of h.b5% of the reflections were used in theR-free calculations.Effects of salt on Vibrio endonucleases L. Niiranen...

Báo cáo khoa học: Effects of cardiomyopathic mutations on the biochemical and biophysical properties of the human a-tropomyosin docx

... by varying the concen-tration of Tm in the presence of constant concentration of F-actin and myosin S1. In this condition, Tm inh ibits theATPase activity as its concentration increases [33]. ... absence of troponin as a function of tropomyosinconcentration, and in the presence of troponin and Ca2+concentration varying from 10)6to 10)3M. InorganicÓ FEBS 2004 Cardiomyopathic mutations ... hepresence of troponins. In the absence of troponins, binding of Tms to actin was very weak and only small amounts of Tm wer e detected in gels after centrifugation (data notshown). The addition of...

Báo cáo khoa học: Effects of juvenile hormone on 20-hydroxyecdysone-inducible EcR, HR3, E75 gene expression in imaginal wing cells of Plodia interpunctella lepidoptera ppt

... effects of 20E both on cell proliferation and morphological changes of IAL-PID2 cells.Isolation and characterization of P. interpunctellaEcR-B1mRNACloning of a PIEcR cDNA frament. We wonderedwhether ... B1 i soform) o f other insect EcRs and a strongdegree of identity was conﬁned to the two ends of N-terminal region of the A/B domain. Using a B1isoform-speciﬁc probe from the A/B region of PIEcR, ... wth conditions f or 36 h. Cells were th en grown f or36 h in Grace’s medium containing no ho rmone or only 20E at 10)7Mor in combinat ion with JH II at various concentrations. At the end of treatment,...

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