... to the
types found in
G,),
therefore c H
aVaa) must be in
Tree,.
All
the
other types found in this tree must
be introduced by hypotheses, and all
the hypotheses introduced have to
be eliminated ... typical in learn-
ability theory.
The negative results for Lambek- like systems
show that this is not the case. Even placing
bounds on the complexity of the types appea...
... recovered,
only the longest amino acid sequences that included
the DNA binding, hinge and ligand-binding domains
were used for this analysis, except for the Knirps fam-
ily members that lack the LBD. In D. ... library
prepared from the fat bodies of vitellogenic female
mosquitoes. They isolated several clones that code
for a single protein. Interestingly, during the initial
proc...
... interpretation in distinguish-
ing interacting from noninteracting proteins. One
Fig. 1. Schematics of library designs. The helical wheel diagram looks down the axis from the N-terminus to the C-terminus. ... focused on small molecule inhibitors, but
the potential of using peptides as the starting point in
the generation of therapeutics is now a growing area
[18,19]. Peptide...
... enzymes
involved in nicotine catabolism will have applications
not only in the bioremediation of nicotine waste, but
also in the supply of nicotine derivatives as starting
materials for the synthesis ... lead to the complete mineraliza-
tion of the pyrrolidine ring of nicotine, which after
oxidation by 6-hydroxy-l-nicotine oxidase, is cleaved
off from the pyridine ring of...
... discussion
The isochores in the chicken genome
It should be noted that the chicken genome sequence
still contains a large number of gaps (Table 1). In the
case of GGA1, there are 9847 gaps remaining. There-
fore, ... denotes the first point
occurring during the course of segmentation, and l and r denote
that the point occurs in the left and right subsequence, respect-
i...
... neuropathology in SE [6]. Despite numerous
studies clearly indicating the importance of enzyme
activity in the epileptic phenomenon, the mechanisms
by which these enzymes in uence SE are not com-
pletely ... concentrations are not
raised in epileptic patients [27]. Other mechanisms may
be associated with the increase in ROS levels in the
epilepsy model as well as...
... unusual in having
two histidine residues (rather than the His-Asn pair
seen in OYE, MR and some of the other member
proteins; Fig. 1B) in the active site for ligand and
substrate binding. For ... role in the binding of phenolic compounds
in the active site [3,26]. Likewise, in MR the counter-
part residues His186 and Asn189 form key interactions
with reducing nicotinam...
... were
remaining vs. 50–60% of the membrane fraction.
These results are consistent with the idea that the
Ga subunits are more stable in the membrane than in
the cytoplasm. To study this further we ... RGS domain in the amino-terminus of G
protein-coupled receptor kinase 2 inhibits Gq-mediated
signaling. Int J Mol Med 5, 335–340.
20 Chen CA & Manning DR (2001) Regulati...
... extracts used in the assay system.
We observed that during in vitro cultivation, the L3 could
not develop and molt to L4 in the presence of inhibitor, even
at the end when the culture had terminated ... determined by incubating the diluted recombin-
ant proteins in the standard reaction mixture in the presence
of increasing concentrations of PP
i
(0.05–0.5 m
M
)at5...
... control of the underlying applica-
tion. Figure 1 shows screen shots of the COMIC
interface.
There are four main phases in the demonstra-
tor. First, the user specifies the shape of their
own bathroom, ... bound-
ary tones are selected by the realiser based on the
context-sensitive information-structure annotations
(theme/rheme; marked/unmarked) included in the
logical...