... promoting an increase in
proopiomelanocortin and cocaine and amphetamine
regulated transcript. Taken together, these findings
provide a compelling argument for the role for malo-
nyl-CoA in regulating ... and certain amino acids [16].
A linkage between fatty acid synthesis in the CNS
and feeding behavior was uncovered with the finding
that systemic or intracerebroventricular adminis...
... the meta-
llation mechanisms of the individual domains, in the
hope, initially, of simplifying the interpretation of
the metallation details of the two-domain protein. The
results presented here ... investigated the metal-binding reactivity of the
isolated a domain of human metallothionein isoform 1a, with specific
emphasis on resolving the debate concerning...
... were raised in rabbits
against a GST-War1p fusion protein containing 294 amino
acids of the C-terminal part of War1p (amino acids 650–
944) fused in- frame to the C-terminus of GST. The gene
fusion ... DNA-binding zinc
cluster at the N-terminus, whereas the acidic activation
domain is usually present at the C-terminus. The mid-
dle homology region (MHR) bridging the D...
... defining the set of
items that have ever been the actor in a flight. Their definition is
solely within NIKL using the QUA link [14], which is exactly the set of
fillers of a slot. While having ... expressions in inten-
sional logic. 3
4. Use of the Taxonomy in Janus
By domain mode/we mean the set of axioms en-
coded in NIKL regarding the constants. The...
...
meanings).
2. the meaning of the rules (rule meanings).
In Montague Grammar these meanings are ex-
pressed in intensional logic. In the Rosetta system
the meanings of rules and basic expressions ... If we combine this
principle with the Isomorphy Principle, the main
consequence is that the semantic derivation trees
constitute the intermediate language and tha...
... examination of the polyubiquitination
of mutant SOD1 using FRET may be useful for inves-
tigating the details of the role of the ubiquitin–protea-
some system in neurodegenerative diseases in ... analysis of HSP70–YFP in Huntingtin-
150Q–CFP inclusions revealed that HSP70 is mobile
within the inclusion [20]. As the movement of HSP70 is
significantly slower in t...
... inhi-
bitor of growth protein 3 (ING3) PHD, which is
another domain involved in chromatin binding and
clearly more divergent (e-value 0.019) from DIDO and
the other sequences. As the alignment ... from the other bran-
ches, which was indeed predicted. The other main
group, obtained 97% of the time in 20 740 explored
trees, contained the DIDO PHD sequences clustered
with...
... [41]. In the present
study, most of the proteins from both EDTA-SM and
WSMmigratedinthegelwithnodistinctpattern,leavinga
dark continuous smear after silver staining (Fig. 4). No
discrete individual ... acid-rich
glycoproteins would be present both within the silk gel prior
to mineralization and also as electron-dense patches at the
surface of b-chitin. The presence of chitin...
... near
the N- and C-termini of the linkers: this suggests that
a mobile connection with both the catalytic domain
and the binding module is required for the function of
the nanomachine. Furthermore, ... spring, allowing
the nanomachine (catalytic domain–linker–binding
module) to crawl on the substrate surface. The possible
functional implications of the linker primary...
... Yer-
sinia, the increased synthesis of LcrV triggered by the
activation of the system leads to the titration of LcrG,
which binds LcrV in a 1 : 1 complex. In turn, this
results in a release of the ... by the sug-
gestion that pH sensing by Salmonella involves modi-
fications in the assembly of the translocon, which
affect the pH gradient within the needle,...