... present in the cytosolfraction (caspase-2, -3, -6, -7, -8 and -9) of living cells to separate silent precursor caspases in the cytosol from pro-apoptotic cofactors in the mitochondria and nucleus ... Ser112 and Ser136, Bad is dephospho-rylated at Ser155, which allows translocation to mitochondria and the binding of Bcl-xL [86], and increases the release of cytochrome c from mitochon-dria into ... inhibitor of CAD[14,24].Mitochondrial DNA fragmentation-inducingfactor: EndoG, AIFSeveral pro-apoptotic proteins exist in mitochondria and are released during apoptosis. These includeapoptosis-inducing...