... Biology, Shandong Provincial Research Center for Bioinformatic Engineering and Techniques,Shandong University of Technology, Zibo, China2 Department of Physics, Tianjin University, ChinaFrom the 1970s ... by a straight line using the least square technique,z ¼ kn ð2Þwhere (z, n) is the coordinate of a point on the straightline fitted and k is its slope. Instead of using the curve of zn% n, we ... spindle attachment and maintaining sister chromatid cohesion [22]. Becausecentromere regions are heterochromatic and containtandem repeats arrays, the genomic organization of centromere remains...