Báo cáo khoa học: Reactions of gold(III) complexes with serum albumin docx
Báo cáo khoa học: Reactions of gold(III) complexes with serum albumin docx
... hydrophobic molecules; more-over albumins bind various metal ions [8].The reactions of gold(III) complexes with serum albumin were investigated primarily through the analysis of theCorrespondence to ... thesubject of further biochemical and pharmacological inves-tigations [1]. Studies of the interactions of these gold(III) complexes with DNA, the classical target of platinum(II) complexes, ... [2,3].Surprisingly, at variance with the reactions with nucleicacids, the reactions of antitumour metal complexes with proteins have been poorly explored until now although theymay be of extreme relevance...
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Báo cáo khoa học: Recruitment of transcription complexes to the b-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells docx
... andtemporal expression of specific subsets of genes. Thesequential silencing of genes involved in maintenance of pluripotent and multipotent states and the activa-tion of those involved in differentiation ... transcription complexes, often referred to as transcription factories [30]. It ispossible that one of the early events in globin locusactivation involves the association of the LCR with transcription ... 2006 FEBS 755Recruitment of transcription complexes to the b-globinlocus control region and transcription of hypersensitivesite 3 prior to erythroid differentiation of murineembryonic stem...
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Tài liệu Báo cáo khoa học: Effects of sequestration on signal transduction cascades docx
... a large amount of enzyme–substratecomplex compared with the total concentration of theinterconvertible enzyme may reduce the sensitivity of the cycle. They did not analyse any of the general ... transduction cascades often exhibitcomparable amounts of protein substrates and enzymes[16]. For example, the individual concentrations of Table 1. Concentrations of members of the MAPK cascade(MAPKKK, ... expressedthe response of the active fraction to a change of thekinase concentration as a function of the concentra-tions of the two forms ([T] and [T*]) and the elastici-ties of the enzymes by...
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Tài liệu Báo cáo khoa học: Association of feather colour with constitutively active melanocortin 1 receptors in chicken docx
... points, independent of concentration of a-MSH, as compared with the non-transfected cells. The cells transfected with hMC4-E100K,in contrast with the chicken receptors with Lys in position92, ... concentrations of a-MSH, thecAMP levels were lower than that observed for the cellstransfected with eb,Eand ER. All experiments wereperformed with a similar number of cells; the amount of protein ... the synthesis of bothclasses of melanin pigments, eumelanin and phaeomelanin.A low level of tyrosinase expression leads to increasedphaeomelanin synthesis, while elevated levels of tyrosinase,that...
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Báo cáo khoa học: Interactions of imidazoline ligands with the active site of purified monoamine oxidase A potx
... within 3 A˚ of N5 of the isoalloxazine ring of the flavin. Agmatine, however,binds poorly to MAO-A, giving only 50% inhibition of the oxidation of 0.3 mm kynuramine at 1 mm.Docking of imidazolines ... inhibition of MAO with a mechanism-based irreversible inhibitor did not prevent binding of the I2ligand 2-(2-benzofuranyl)-2-imidazoline (2-BFI),suggesting that the I2BS was not the active site of MAO ... thebinding of imidazolines to the active site of purifiedMAO-A. The representative I2BS ligands used are lin-ear competitive inhibitors of purified MAO-A, inagreement with the data of Ozaita...
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Báo cáo khoa học: "Boosting-based parse reranking with subtree features" docx
... First, the algorithm starts with a set of treesconsisting of single nodes, and then expands a giventree of size (n−1) by attaching a new node to it toobtain trees of size n. However, it would ... highlycorrelated with each other. Even when we exploit allsubtrees, most of them are extremely redundant.The motivation of this paper is based on the aboveobservation. We think that only a small set of ... for each task. Kernel methods offer an ele-gant solution to these problems. They can work on apotentially huge or even infinite number of featureswithout a loss of generalization. The best knownkernel...
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Tài liệu Báo cáo khoa học: Structure of RNase Sa2 complexes with mononucleotides – new aspects of catalytic reaction and substrate recognition pptx
... [33], with yields of 10–50 mg from 1 L of cul-ture medium. The crystallization of RNase Sa2 with a freeactive site was performed as described previously [32]. Complexes of RNase Sa2 with 2¢-GMP ... command of glide. Interactions of probe atoms with proteins werecalculated with the Receptor Grid Generation command of V. Bauerova´-Hlinkova´et al. Structures of RNase Sa2–mononucleotide complexes FEBS ... positional constraint of 4.5 A˚between thegeometrical center of the main chain nitrogen of Arg42 andO6 of the leading guanine. Accuracy of the docking wasassessed on the basis of scoring values...
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Báo cáo khoa học: The oleic acid complexes of proteolytic fragments of a-lactalbumin display apoptotic activity pdf
... (2005) Conversion of human alpha-lactalbumin toan apo-like state in the complexes with basic poly-amino acids: toward understanding of the molecularmechanism of antitumor action of HAMLET. J Prote-ome ... acid complexes of a-lactalbumin fragmentsFEBS Journal 277 (2010) 163–173 ª 2009 The Authors Journal compilation ª 2009 FEBS 173The oleic acid complexes of proteolytic fragments of a-lactalbumin ... of the various OA complexes could result froman enhanced solubility of the otherwise poorly solubleand inherently toxic fatty acid [33].ResultsPreparation of complexes of a-LA fragmentswith...
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Báo cáo khoa học: Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast ppt
... at 4 °C with 250 lL of phenol ⁄ chloroform (5 : 1, pH 4.7) and100 lL of Zirconia beads (Ambion, Applied Biosystems,Warrington, UK). The aqueous phase was mixed with anequal volume of 2 · RNA ... Lsm8p N-termini prevent aggregation of the Lsm complexes, potentially by interacting with the prion-like C-terminal domain of Lsm4p. This asparagine-richregion of Lsm4p plays a role in Lsm1–7p ... related to SmB, with itsC-terminus also containing a high level of basic lysineresidues. However, although deletion of most of theC-terminus abolishes nuclear accumulation of theN-terminally...
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Báo cáo khoa học: "Impact of computerized physician order entry on medication prescription errors in the intensive care unit: a controlled cross-sectional trial"
... one unit of our ICU, we implemented an ICIS with incorpo-rated CPOE and a moderate level of CDSS. The objective of this study was to evaluate and compare the incidence andseverity of medication ... completely unaware of the ongoing study. As itwas not possible to screen every patient on a daily basisbecause of lack of time, patients were picked with a minimalpause of one day between ... example of intercepted MPEinvolved the wrong prescription of a tenfold overdose of abeta-blocker, where rapid intervention of the clinical pharma-cist intercepted the administration of this...
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Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ