... close to the main chain of the cata-lytic aspartates forming new van der Waals contactsand a C-HÆÆÆO interaction. These new contacts with Asp25 ⁄ 25’ near the dimer interface correlate with the reduced ... National Insti-tutes of Health grant GM062920. We thank the staff atSER-CAT beamline at the Advanced Photon Source,Argonne National Laboratory, Argonne, IL, USA, forassistance during X-ray data ... Molecular Basis of Disease Program, Georgia State University, Atlanta, GA, USA2 Department of Computer Science, Molecular Basis of Disease Program, Georgia State Univers’ity, Atlanta, GA, USA3 Department...