... to
subsequent strands of b-sheet (Fig. 1). We have investigated
the context-dependent effects of mutations at these sites on
Fig. 6. Chevron plot analysis of the logarithm
of the r efolding and unfolding ... substitutions imposed on the
backbone conformation of WT* shows that the pattern of
P37
P38
P19
W45
Fig. 1. Ribbon structure modelled on the X-ray stru...
... sbwAFP
(red, residues G ly34 to T hr49) and TmAFP (blue, residues
Asn29fiGly41). Letters de note the five residues of on e of the three
sides of s bwAFP o r s ix residues of on e of two sides of T mAFP. ... so, a considerable number of questions remain
before we can solve the interaction at the atomic level and
understand t he role of the threonine side...
... depending on the input, interconnections
to other information, and an automatic activity
decay scheme. In addition, the decay scheme is
based on the state of the information, whether it
has ... result of acti-
vation of a pragmatic representation of a
disambiguated word meaning.
It is the in interaction of the results of
these asynchronous processes that...
... to continue processing the rest of the
input data if the workflow is robust (i.e. makes
use of retry and parallelisation) and the error is
confined to a WS (i.e. it does not affect the rest of
the ... factory of LRs that
automates the stages involved in the acquisition,
production, updating and maintenance of LRs
required by Machine Translation (MT), and by
oth...
... (Fig. 3C). On the other hand, the
SOD2 mutation reporter [SOD2 )1500 ⁄ )1335(T)]
showed no effect of either BetA, overexpression of
CREB in the presence of BetA, or siCREB alone,
further demonstrating ... (2007) DNA bind-
ing and phosphorylation induce conformational altera-
tions in the kinase-inducible domain of CREB.
Implications for the mechanism of transcription f...
... polarity-classification, the
last proposition of a given text should be of
greater importance than the first one (contrary
to topic-extraction).
Based on preliminary investigations, we sug-
gest that the DT of ... session and had an unlimited time to
reflect and decide on the polarity of each text.
Five seconds after a decision was made (as to
whether the revi...
... efficiently than the N-terminal portion
of the protein. The Nop53p N-terminal region, on the
other hand, is involved in RNA interaction and can
partially complement the conditional strain Dnop53 ... the proteins in the pre-60S complex,
but is less concentrated in the nucleolus. These results
raised the question of whether any of the truncated
mutants of Nop53p,...
... up 60–65% of the compositions of 5a
and 5a-like protein and 55% of ApAFP. Of the other
amino acids, Thr (13%) is the next most abundant,
and there are very low amounts of aromatic and long-
chain ... concentrations, thermal
hysteresis readings were done on dilutions of pure
ApAFP in 1 mgÆmL
)1
BSA. The plot of TH as a func-
tion of ApAFP concentration with al...
... k
H
2
O
U
is the unfolding rate constant in the absence of
urea and m
U
à
the dependence of the unfolding rate con-
stant on urea concentration. The free energy of activation
for the unfolding of KSI-PI ... hydrophobic
packing of the SEHC is important for the conforma-
tional stability of KSI-PI. The stability of L125A ⁄
V127A was decreased by 0.9 kcalÆ...
... mitochon-
drial isolation. The mixtures were pre-incubated for 3 min
at 37 °C and then the reactions were initiated by addition
of 120 lm NADPH. The incubations were carried out for
10 min and then ... between
residues 23–33 and that the positively-charged residues at positions 24, 25,
26, 28 and 32 are required for mitochondrial targeting. The importance of
the po...