Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx

Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx

Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx

... to subsequent strands of b-sheet (Fig. 1). We have investigated the context-dependent effects of mutations at these sites on Fig. 6. Chevron plot analysis of the logarithm of the r efolding and unfolding ... substitutions imposed on the backbone conformation of WT* shows that the pattern of P37 P38 P19 W45 Fig. 1. Ribbon structure modelled on the X-ray stru...
Ngày tải lên : 07/03/2014, 16:20
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf

Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf

... sbwAFP (red, residues G ly34 to T hr49) and TmAFP (blue, residues Asn29fiGly41). Letters de note the five residues of on e of the three sides of s bwAFP o r s ix residues of on e of two sides of T mAFP. ... so, a considerable number of questions remain before we can solve the interaction at the atomic level and understand t he role of the threonine side...
Ngày tải lên : 19/02/2014, 16:20
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Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

... depending on the input, interconnections to other information, and an automatic activity decay scheme. In addition, the decay scheme is based on the state of the information, whether it has ... result of acti- vation of a pragmatic representation of a disambiguated word meaning. It is the in interaction of the results of these asynchronous processes that...
Ngày tải lên : 21/02/2014, 20:20
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Tài liệu Báo cáo khoa học: "Language Resources Factory: case study on the acquisition of Translation Memories" potx

Tài liệu Báo cáo khoa học: "Language Resources Factory: case study on the acquisition of Translation Memories" potx

... to continue processing the rest of the input data if the workflow is robust (i.e. makes use of retry and parallelisation) and the error is confined to a WS (i.e. it does not affect the rest of the ... factory of LRs that automates the stages involved in the acquisition, production, updating and maintenance of LRs required by Machine Translation (MT), and by oth...
Ngày tải lên : 22/02/2014, 03:20
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Báo cáo khoa học: Betulinic acid-mediated inhibitory effect on hepatitis B virus by suppression of manganese superoxide dismutase expression pot

Báo cáo khoa học: Betulinic acid-mediated inhibitory effect on hepatitis B virus by suppression of manganese superoxide dismutase expression pot

... (Fig. 3C). On the other hand, the SOD2 mutation reporter [SOD2 )1500 ⁄ )1335(T)] showed no effect of either BetA, overexpression of CREB in the presence of BetA, or siCREB alone, further demonstrating ... (2007) DNA bind- ing and phosphorylation induce conformational altera- tions in the kinase-inducible domain of CREB. Implications for the mechanism of transcription f...
Ngày tải lên : 16/03/2014, 01:20
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Báo cáo khoa học: "Last but Definitely not Least: On the Role of the Last Sentence in Automatic Polarity-Classification" pdf

Báo cáo khoa học: "Last but Definitely not Least: On the Role of the Last Sentence in Automatic Polarity-Classification" pdf

... polarity-classification, the last proposition of a given text should be of greater importance than the first one (contrary to topic-extraction). Based on preliminary investigations, we sug- gest that the DT of ... session and had an unlimited time to reflect and decide on the polarity of each text. Five seconds after a decision was made (as to whether the revi...
Ngày tải lên : 23/03/2014, 16:20
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Báo cáo khoa học: Nop53p interacts with 5.8S rRNA co-transcriptionally, and regulates processing of pre-rRNA by the exosome ppt

Báo cáo khoa học: Nop53p interacts with 5.8S rRNA co-transcriptionally, and regulates processing of pre-rRNA by the exosome ppt

... efficiently than the N-terminal portion of the protein. The Nop53p N-terminal region, on the other hand, is involved in RNA interaction and can partially complement the conditional strain Dnop53 ... the proteins in the pre-60S complex, but is less concentrated in the nucleolus. These results raised the question of whether any of the truncated mutants of Nop53p,...
Ngày tải lên : 30/03/2014, 04:20
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Tài liệu Báo cáo khoa học: Hyperactive antifreeze protein in flounder species The sole freeze protectant in American plaice docx

Tài liệu Báo cáo khoa học: Hyperactive antifreeze protein in flounder species The sole freeze protectant in American plaice docx

... up 60–65% of the compositions of 5a and 5a-like protein and 55% of ApAFP. Of the other amino acids, Thr (13%) is the next most abundant, and there are very low amounts of aromatic and long- chain ... concentrations, thermal hysteresis readings were done on dilutions of pure ApAFP in 1 mgÆmL )1 BSA. The plot of TH as a func- tion of ApAFP concentration with al...
Ngày tải lên : 20/02/2014, 01:20
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Báo cáo khoa học: Small exterior hydrophobic cluster contributes to conformational stability and steroid binding in ketosteroid isomerase from Pseudomonas putida biotype B pot

Báo cáo khoa học: Small exterior hydrophobic cluster contributes to conformational stability and steroid binding in ketosteroid isomerase from Pseudomonas putida biotype B pot

... k H 2 O U is the unfolding rate constant in the absence of urea and m U à the dependence of the unfolding rate con- stant on urea concentration. The free energy of activation for the unfolding of KSI-PI ... hydrophobic packing of the SEHC is important for the conforma- tional stability of KSI-PI. The stability of L125A ⁄ V127A was decreased by 0.9 kcalÆ...
Ngày tải lên : 23/03/2014, 13:20
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Báo cáo khoa học: Human liver mitochondrial cytochrome P450 2D6 – individual variations and implications in drug metabolism docx

Báo cáo khoa học: Human liver mitochondrial cytochrome P450 2D6 – individual variations and implications in drug metabolism docx

... mitochon- drial isolation. The mixtures were pre-incubated for 3 min at 37 °C and then the reactions were initiated by addition of 120 lm NADPH. The incubations were carried out for 10 min and then ... between residues 23–33 and that the positively-charged residues at positions 24, 25, 26, 28 and 32 are required for mitochondrial targeting. The importance of the po...
Ngày tải lên : 29/03/2014, 23:20
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