... FEBS Promoters of type I interferon genes from Atlantic salmon contain two main regulatory regions Veronica Bergan, Silje Steinsvik, Hao Xu, Øyvind Kileng and Børre RobertsenDepartment of Marine Biotechnology, ... transcription start site of their promoters [19]. The IFN-b promoter contains fourpositive regulatory domains (PRDs), which bind IRFs:mainly IRF-3 and IRF-7 (PRDI and PRDIII), NF jB(PRDII) and ... medium; IFN, interferon; IPNV, infectious pancreatic necrosis virus; IRF, interferon regulatory factor; IRF-E, interferon regulatory factor binding element; ISAV, infectious salmon anemia virus;...