Báo cáo khoa học: Fowlicidin-3 is an a-helical cationic host defense peptide with potent antibacterial and lipopolysaccharideneutralizing activities ppt
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viewpoint and report some other observations
and issues in our experiments.
5.1 Comparison with Previous Work
This is to explain more about why our method
performs better...
... 25
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Fig. 5. His41 is essential for Paracoc-
cus pantotrophus NirF, but Asp129 is dis-
pensable. Growth plots and time courses of
nitrite appearance and disappearance for
P. pantotrophus SBN11 ... conserved
between NirF and NirS; it is the His residue that in
NirS is the proximal axial ligand to the d
1
heme.
Rep...
... of PDI,
and many have been shown to catalyze thiol–disulfide
exchange reactions. However, their specific roles,
substrate specificities and mechanisms of cooperation
with other catalysts and chaperones ... Bacitracin is not a specific inhibitor of protein disulfide
isomerase
Anna-Riikka Karala and Lloyd W. Ruddock
Biocenter Oulu and Department of Biochemistry, University of Oulu, Fin...
... tumorigenesis
The challenge of cross-platform analysis of cancer
microarray data was presented by Roland Eils (Heidel-
berg), who uses median rank scores and quantile dis-
cretization to derive numerically ... through membrane blebbing and
autophagic cell death. Two closely related kinases,
ZIPk and DRP-1, mediate trans-phosphorylation and
subsequent functional activation of ZIPk. DAP...
... (asperellum and harzianum) could be related to
differences in antagonistic behaviour and ⁄ or host range
between these strains and perhaps between the two bio-
types. In connection with this idea, it is ... polymers with glycosidic linkages using
0.5 mgÆmL
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of each substrate: mutan (a-1,3- and a-1,6-glu-
can), nigeran (a-1,3- and a-1,4-glucan), soluble starch
(a-1,4- and...
... Visfatin ⁄ PBEF ⁄ NAMPT is synthesized and
secreted in adipose tissue by adipocytes, and mostly
by macrophages, and circulates in the plasma of
humans and mice [4]. Plasma concentrations of visfa-
tin ... vitro translation and EMSA
PPARc and RXRa were in vitro transcribed from the
pSG5–hPPARc and pSG5–hRXRa plasmids, respectively,
using T7 polymerase, and subsequently transl...
... 4897
Acknowledgements
We thank Zhong Yu and Edwin van Bloois for helpful
discussions, and Sergei Sukharev (Department of
Biology, University of Maryland, MD, USA) for pro-
viding MscL plasmids and strains. O.P. is supported
by ... membrane protein biogenesis
because it is small and, after membrane insertion,
assembles into a pentameric complex for which the
structure is known [11...
... mutant, and the LEX2 mutant were all
grown under humidified conditions at 37 °C and 5% CO
2
in Ham’s F-12 media (Gibco BRL, Grand Island, NY,
USA) supplemented with 10% fetal bovine serum (Atlanta
Biologicals, ... for example, is an anticancer
toxin that consists of a chemical conjugate between the human uPA and
native saporin. Both saporin and uPA-saporin enter the target cell b...
... membrane
hydrolysis and prostaglandin production in a manner
distinct from other intracellular phospholipases A2.
J Biol Chem 280, 14028–14041.
32 Mancuso DJ, Han X, Jenkins CM, Lehman JJ, Sam-
bandam ... versatile and dynamic organelles engaged in
the b-oxidation of long and very long chain fatty
acids, in a-oxidation, bile acid and ether lipid synthe-
sis, and in amino acid and...
... the program
prism (GraphPad Software, San Diego, CA).
Acknowledgements
This work was supported by grants from the Heart
and Stroke Foundation of Canada (grant T4134) and
the Canadian Institutes ... complex by ATP binding and hydrolysis
Zvezdana Popovic and Douglas M. Templeton
Laboratory Medicine and Pathobiology, University of Toronto, Canada
Mechanisms of post-transcriptional regu...