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Báo cáo khoa học: Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes pdf

Báo cáo khoa học: Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes pdf

Báo cáo khoa học: Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes pdf

... EMSAFluorescence quenchingResult Average Kd(nM)AAAGACATG + + 0.25 A GAGACATG ND –AAGGACATG ND –AAATACATG ––AAAGCCATG ––AAAGAGATG + + 1.5AAAGACCTG ND –AAAGACACG ND + 4AAAGACAT A ... was similar (3.0 ± 1.1) to that A BCshifted123123456bandProbe1.00E+008AAAGAGATGAAGGACATGAAAGACCTGAAAGACATGKd=1.2 nMAAAGAGATGKd=0.29 nMAAAGACACGKd=4 nMAAAGACACGAAAGACATAAGAGACATGAAAGACATGAAAGCCATGAAATACATG8.00E+0076.00E+0074.00E+0072.00E+0070.00E+000141612108Fluoriscence340Fluoriscence340640.00 ... AAAGCCATG (P5), AAAGAGATG (P6), AAAGACCTG (P7), AAAGACACG(P8), and AAAGACAT A (P9), and their complementarysequences CATGTCTCT (P2C), CATGTCCTT (P3C),CATGTATTT (P4C), CATGGCTTT (P5C), CATCTCTTT(P6C),...
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Báo cáo khoa học: Xenopus Rbm9 is a novel interactor of XGld2 in the cytoplasmic polyadenylation complex pptx

Báo cáo khoa học: Xenopus Rbm9 is a novel interactor of XGld2 in the cytoplasmic polyadenylation complex pptx

... oocyte maturation. Proc Natl Acad SciUSA 98, 13728–13733.41 Zhu Y, Bond J & Thomas P (2003) Identification, clas-sification, and partial characterization of genes inhumans and other vertebrates ... thatother transcript -specific complexes are present at the 3¢-UTR of regulated mRNAs.Although cytoplasmic polyadenylation is regulatedby a protein complex at the 3¢-end of the mRNA, PAPis the ... in the regulation of translation. On the one hand, CPEB represses the translation of CPE-containing mRNAs via its interac-tion with other partners, including Maskin, the RNAhelicase Xp54 and...
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Báo cáo khoa học:

Báo cáo khoa học: "Creative Language Retrieval: A Robust Hybrid of Information Retrieval and Linguistic Creativity" pot

... creativeanticipation, acting as a mediator between the lit-eral specification of a meaning and the retrieval of creative articulations of this meaning. This antici-pation ranges from simple re-articulation ... Nonetheless,ad-hoc categories in creative IR are often popu-lated with the bindings produced by uses of @ and ? and combinations thereof. In a sense, ?X and @X and their variations are themselves ... non-literalmatching and automatic query expansion.3 Creative Text RetrievalIn language, creativity is always a matter of con-strual. While conventional IR queries articulate a need for information,...
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Báo cáo khoa học: Functional fine-mapping and molecular modeling of a conserved loop epitope of the measles virus hemagglutinin protein pdf

Báo cáo khoa học: Functional fine-mapping and molecular modeling of a conserved loop epitope of the measles virus hemagglutinin protein pdf

... beenpartially induced against the linear isoform of the HNEpeptide. Although the binding pattern may be somewhatblurred by these antibodies and by the polyclonal nature of the sera, the importance ... phaseformats including surface plasmon resonance (SPR). Bindingdata were corroborated by a molecular model of the epitope and by immunization experiments with peptide-conjugates.Materials and ... peptide was at least partially oxidized and the signal of the reduced species increased as a result of oxidation.Identification of the active isoformBecause of disulfide scrambling HPLC-purified isoformsrapidly...
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Báo cáo khoa học:

Báo cáo khoa học: "GAMR VIEWED AS A FUNCTIONING PART OF A COGNITIVES SERM A YTM" pot

... of each meaning of a phonetic word is also a part of the grammatical representation where it makes associations with other syntactic categories. The associations visible in the grammatical ... grammar, a brief dis- cussion of the structure of the grammar and the role of the grammar in the global nature of the control must be given. 3.2 The Local Representation of the Grammar The ... grammar space representation. Part of the grammatical meaning of any syn- tactic category is the meaning category that is expected to follow it in the input. The other part of the grammatical...
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Báo cáo khoa học: Oxidative stress induces a reversible flux of cysteine from tissues to blood in vivo in the rat pptx

Báo cáo khoa học: Oxidative stress induces a reversible flux of cysteine from tissues to blood in vivo in the rat pptx

... lmolÆmin)1Ækg)1intravenously) and blood withdrawal. Blood was withdrawn 15 minafter the end of diamide infusion and maintained at 37 °C. Timezero indicates the time of withdrawal. Data are the means ± SD of three ... con-centrations of total cysteine in both plasma (black bars) and erythro-cytes (gray bars) to the relative hematocrit value. Values areexpressed as thiol equivalents. Data are the means ± SD of ... oxidative stress on cysteine and glutathioneexchange among tissues. Indeed, the factors that main-tain the redox homeostasis of plasma thiols as well as the mechanisms that regulate the exchange...
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Báo cáo khoa học: E2A participates in a fine control of pre-mature B-cell apoptosis mediated by B-cell receptor signaling via transcriptional regulation of survivin, IAP2 and caspase-8 genes pot

Báo cáo khoa học: E2A participates in a fine control of pre-mature B-cell apoptosis mediated by B-cell receptor signaling via transcriptional regulation of survivin, IAP2 and caspase-8 genes pot

... to a balance of the amounts of each of the threecaspases and the inhibitors survivin and IAP2 (and alsoFLIP and IAP1). The slightly decreased caspase-8 activity mediated by PMA/ionomycin treatment ... inE 2A )/)may have resulted from the balanced mRNA (and probably protein) levels of caspase-8, which leadto activation of pro-caspase-9, causing formation of the active form of caspase-3, and of ... mustdepend on both the reduced amount of activatedcaspase-3 itself as a result of decreased caspase-8 (and probably caspase-9) activity, and the elevated protein (and also mRNA) levels of the inhibitors...
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Báo cáo khoa học:

Báo cáo khoa học: "Extending Lambek grammars: a logical account of minimalist grammars" pot

... by labeling each formula in the proof. Theselabels, that are called phonological and seman-tic features in the transformational tradition, arecomputed from the proofs and consist of two partsthat ... (or feature checking)is their common base, they differ in various re-spects. On the one hand, traditional categorialgrammar has no move operation, and usually have a poor generative capacity ... logical definition of Min-imalist grammars, that are Stabler’sformalization of Chomsky’s minimal-ist program. Our logical definitionleads to a neat relation to catego-rial grammar, (yielding a...
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Báo cáo khoa học: MNB⁄ DYRK1A as a multiple regulator of neuronal development pdf

Báo cáo khoa học: MNB⁄ DYRK1A as a multiple regulator of neuronal development pdf

... Signal 21,1626–1633.84 Kurabayashi N, Hirota T, Sakai M, Sanada K & Fuk-ada Y (2010) DYRK 1A and glycogen synthase kinase3beta, a dual-kinase mechanism directing proteasomaldegradation of ... (2005) Dual-specificitytyrosine-phosphorylated and regulated kinase 1A (DYRK 1A) interacts with the phytanoyl-CoA alpha-hydroxylase associated protein 1 (PAHX-AP1), a brain specific protein. Int ... overproliferation can alter the balance between neu-ronal populations, leading to mental disorders and neuropathologies.MNB ⁄ DYRK 1A has also been implicated in variousaspects of late neuronal differentiation....
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Báo cáo khoa học: Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours pot

Báo cáo khoa học: Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours pot

... interleukin-8), and enzymes that lead to extracellular matrix degra-dation (matrix metalloproteases) [75–78]. In addition,NF-jB activation was reported as an early event inmalignant transformation in ... studiesallowed the demonstration of complete HIF- 1a degra-dation after each cycle of 30 min of reoxygenation,showing that HIF- 1a had not accumulated in the course of intermittent hypoxia cycles, and thereforethat ... glyceraldehyde-3-phosphate dehydro-genase gene) and angiogenesis [e.g. the vascular endo-thelial growth factor (VEGF) gene] [45], thus allowingcells to adapt to hypoxia [46]. The stabilization of HIF-1 a and activation...
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