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Báo cáo khoa học: The organotellurium compound ammonium trichloro(dioxoethylene-o,o¢)tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice pptx

Báo cáo khoa học: The organotellurium compound ammonium trichloro(dioxoethylene-o,o¢)tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice pptx

Báo cáo khoa học: The organotellurium compound ammonium trichloro(dioxoethylene-o,o¢)tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice pptx

... decreased total homocysteine but not totalcysteine levels in hyperhomocysteinemic mice The ability of AS101 to inhibit homocysteine was nexttested in vivo. C57bL ⁄ 6 mice were divided into fourexperimental ... ammonium trichloro(dioxoethylene-o,o ¢)tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice Eitan Okun1,*, Yahav Dikshtein1,*, Alon Carmely1, Hagar ... homocysteine to form homocystine, the lesstoxic disulfide form of homocysteine. Moreover, AS101 was shown here to reduce the levels of total homocysteine in an in vivo model of hyperhomo-cysteinemia....
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Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc

Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc

... specific interactionsbetween cis-acting elements mainly localized in the UTRs of the transcript and the trans-acting factors(RNA-binding proteins and noncoding regulatoryRNAs) that bind to these ... SF2 to induce the destabilization of the mRNA encodingPKCI-related protein by direct binding to a purine-richsequence present in PKCI-r mRNA 3¢ UTR [15]. On the other hand, other studies indicated ... SF2 relocalized into the cytoplasm in response to stress and accumulated in bona fideSGs. Furthermore, the results obtained in the presentstudy indicate that ASF ⁄ SF2 migration into SGsstrongly...
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Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

... literature: the dominant polymorpha-chitin (antiparallel packing of the chitin chains);b-chitin (parallel packing of the chitin chains); and the minor polymorph c-chitin (mixture of parallel and antiparallel ... to gain access to and degrade individualpolymer chains. First, the chains are degraded by bothendochitinases, that attack the chitin chain randomly, and exochitinases, that attack the chitin ... importance of chitin-binding proteins in chitin turnover, and provide the first example of a family 33 chitin-bindingprotein that increases chitinase efficiency towards a-chitin.AbbreviationsCBM,...
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Tài liệu Báo cáo khoa học: The RNA recognition motif, a plastic RNA-binding platform to regulate post-transcriptional gene expression ppt

Tài liệu Báo cáo khoa học: The RNA recognition motif, a plastic RNA-binding platform to regulate post-transcriptional gene expression ppt

... determined. In all five cases, the two RRMs and the interdomain lin-ker cooperatively bind RNA providing high affinity and specificity. In the free forms of sex-lethal and nucleolin, the linkers ... and ⁄ or as a hydrogen bond donor interacting with the carbonyl oxygen of the protein backbone [38].Other parts of the RRM domain, such as the b2-strand and the loops, also interact with the ... proteins contain both RRM and auxiliary domains, such as zinc fingers, also involved in nucleic acid binding. No structural studies, how-ever, indicate if these two RNA-binding domainswithin the same...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "The QuALiM Question Answering Demo: Supplementing Answers with Paragraphs drawn from Wikipedia" ppt

... article with title “Franz Kafka” and to expect the answer in the text on that page. For the question “Who invented the automobile?” on the other hand, it is more reasonable to search the information ... intentionbehind this mode of presentation is to prominentlydisplay the piece of information the user is most in- terested in, but also to present context information and to furthermore provide ... title of the Wikipedia article the para-graph is from, Headers, which lists the title and allsection and subsection headings indicating the posi-tion of the paragraph in the article and Text,...
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Tài liệu Báo cáo khoa học: The resident endoplasmic reticulum protein, BAP31, associates with c-actin and myosin B heavy chain Analysis by capillary liquid chromatography microelectrospray tandem MS ppt

Tài liệu Báo cáo khoa học: The resident endoplasmic reticulum protein, BAP31, associates with c-actin and myosin B heavy chain Analysis by capillary liquid chromatography microelectrospray tandem MS ppt

... the interaction betweenactin and myosin in the actomyosin complex [19,20]. The acetylation of the N terminus removes a positive charge and increases the interaction between actin and myosincompared ... maintained a normal c-actindistribution within the cell in contrast with the parental KBcells [9] whereas the ectopic expression of p20 BAP31(lacking the 8 kDa C-terminal segment containing ... contained a free N terminus. In contrast with many other acetylated proteins, removal of the initiatormethionine residue and acetylation of the glutamic acidresidue is important in regulating the...
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Báo cáo khoa học: The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand pptx

Báo cáo khoa học: The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand pptx

... which forms one of the internal borders of the ligand-binding pocket. The side chain of W318 itself isdirected into the ligand-binding pocket. Thus, the trypto-phan is in a position to potentially ... into the ligand-binding pocket cavity (and not interacting with secondary recep-tor structures or extending to the receptor surface to interact with coactiva-tors, corepressors or receptor dimer ... [47] showthat the side chains of these conserved cysteine and histi-dine residues point into the cavity of the ligand-bindingG. Jones et al. Nanomolar binding of methyl farnesoate to USPFEBS...
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Báo cáo khoa học: The optimization of protein secondary structure determination with infrared and circular dichroism spectra docx

Báo cáo khoa học: The optimization of protein secondary structure determination with infrared and circular dichroism spectra docx

... scaling factordetermined by Fourier self-deconvolving the spectra, deter-mining the tyrosine band a rea ratios at 1518 cmÀ1,andthenusing this as the scaling factor for subtracting the originalspectra ... baseline-correction was notused, the first value in the band was subtracted from allother data points in order to bring the minimum to zero.Combination of CD and IR spectra To analyze combined ... sidechain spectrum was generated using the amino acidcomposition of the protein listed in the SWISS-PROTdatabase [38,39]. The side chain spectrum was thensubtracted from the protein spectrum u sing...
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Báo cáo khoa học: The mystery of nonclassical protein secretion A current view on cargo proteins and potential export routes pdf

Báo cáo khoa học: The mystery of nonclassical protein secretion A current view on cargo proteins and potential export routes pdf

... classical secretory proteinsinto the endoplasmic reticulum, import of proteins intomitochondria and peroxisomes, as well as protein importinto and export from the nucleus), are understood in greatdetail. ... FGF-1 homodimer in the cyto-plasm. These are a cleavage product of the transmembraneprotein synaptotagmin consisting of its cytoplasmic domain(p40-Syt1) and the Ca2+-binding protein S100A13. ... processing of IL-1a involves myristoylation and, following insertion into the plasma membrane, calpain-dependent cleavage that is thought to cause release of the mature form of IL-1a into the extracellular...
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Báo cáo khoa học: The leech product saratin is a potent inhibitor of platelet integrin a2b1 and von Willebrand factor binding to collagen pdf

Báo cáo khoa học: The leech product saratin is a potent inhibitor of platelet integrin a2b1 and von Willebrand factor binding to collagen pdf

... demonstrate that saratin interferes with inte-grin a2b1binding to collagen in addition to inhibiting von Willebrandfactor–collagen binding, presumably by binding to an overlapping epitopeon collagen. ... demonstrates that saratin interferes with integrina2b1binding to collagen, in addition to inhibitingVWF–collagen binding, presumably by binding to anoverlapping epitope on collagen. This ... a2b1–collagen interactions.Inhibition of a2integrin subunit I domain binding to collagen by saratin In an attempt to determine whether the binding site oncollagen for the platelet receptor a2b1is...
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