... decreased total homocysteine but not totalcysteine levels in hyperhomocysteinemic mice The ability of AS101 to inhibit homocysteine was nexttested in vivo. C57bL ⁄ 6 mice were divided into fourexperimental ... ammonium trichloro(dioxoethylene-o,o ¢)tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice Eitan Okun1,*, Yahav Dikshtein1,*, Alon Carmely1, Hagar ... homocysteine to form homocystine, the lesstoxic disulfide form of homocysteine. Moreover, AS101 was shown here to reduce the levels of total homocysteine in an in vivo model of hyperhomo-cysteinemia....