... high-light the relevance of CD44v isoforms in cancer whichseem to be suitable targets for anti -cancer therapy. Inseveral primary and cancer cells, CD44v6 forms a ter-nary complex with HGF and ... are responsible for maintaining thetumor and, possibly, for the formation of new tumorsat metastatic loci. CD44 has been identified as animportant marker of such a population of cancer stemcells ... Acad Sci USA 100, 3983–3988.80 Simeone DM (2008) Pancreatic cancer stem cells:implications for the treatment of pancreatic cancer. Clin Cancer Res 14, 5646–5648.81 Du L, Wang H, He L, Zhang J,...