Báo cáo khoa học: Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants potx

Báo cáo khoa học: Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants potx

Báo cáo khoa học: Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants potx

... FEBS. No claim to original French government works 735 Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants Vincent Sauveplane 1 , ... unsaturated C 18 fatty acids. This is also the first report describing a cytochrome P450 which can catalyze the epoxidation of f...
Ngày tải lên : 07/03/2014, 03:20
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Tài liệu Báo cáo khoa học: Arabidopsis thaliana BTB⁄ POZ-MATH proteins interact with members of the ERF⁄AP2 transcription factor family ppt

Tài liệu Báo cáo khoa học: Arabidopsis thaliana BTB⁄ POZ-MATH proteins interact with members of the ERF⁄AP2 transcription factor family ppt

... BPM1 version of 151 amino acids [BPM1(1–151)] comprising the first 38 amino acids of BPM1 followed by the com- plete MATH domain. As shown in Fig. 2A, BPM1(1– 151) is entirely capable of binding to GST:RAP2.4, ... assemble with other proteins either in the nucleus or the cyto- plasm. Discussion This work provides novel information, including the first descrip...
Ngày tải lên : 18/02/2014, 06:20
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Báo cáo khoa học: Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells pptx

Báo cáo khoa học: Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells pptx

... C-terminus of PEA is essential for the cytotoxicity of the endocytosed toxin, allowing PEA to reach its site of action [2,5]. This implies that PEA may interact with the KDEL receptor in order to traffic ... oocytes, but the oocytes could be pro- tected from autointoxication by injecting neutralizing antisaporin antibodies into the cytosol [22]. The mechanism(s) under...
Ngày tải lên : 23/03/2014, 15:21
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Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx

Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx

... grouped into three main classes of PDZ binding motifs, occurring at the C-terminus of the interacting proteins [16]. We scanned the human olfactory receptor repertoire for putative binding motifs ... tested binding of single PDZ domains 1 + 2, and found that both could bind to the OR C-terminus (Fig. 2D). Next, we investigated the ability of PDZ domains 1 + 2 to bind to...
Ngày tải lên : 18/02/2014, 13:20
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Tài liệu Báo cáo khoa học: Rotary F1-ATPase Is the C-terminus of subunit c fixed or mobile? docx

Tài liệu Báo cáo khoa học: Rotary F1-ATPase Is the C-terminus of subunit c fixed or mobile? docx

... suggested the unwinding of the single a-helix at the C-terminal portion of c, thus allowing for unimpaired rotation of the remainder of c.Furthermore, the calculations suggested the very end of c to ... summarized in Fig. 5. The emerging picture is that the central shaft of F 1 never comes to a full halt; c is free to slowly rotate back and forth in...
Ngày tải lên : 19/02/2014, 16:20
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Báo cáo khoa học: VEGF gene expression is regulated post-transcriptionally in macrophages pdf

Báo cáo khoa học: VEGF gene expression is regulated post-transcriptionally in macrophages pdf

... cloned into the 3¢ UTR of the luciferase gene of 3.1-luc. The VEGF-FL-luc construct contains nt 209–1747 of the mVEGF 3¢ UTR where nt 1 is the first base of the VEGF stop codon [34] (identical to ... 2005) doi:10.1111/j.1742-4658.2006.05106.x The macrophage is critical to the innate immune response and contributes to human diseases, including in ammatory...
Ngày tải lên : 07/03/2014, 12:20
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Báo cáo khóa học: ICAM-1 expression is highly NF-jB-dependent in A549 cells No role for ERK and p38 MAPK docx

Báo cáo khóa học: ICAM-1 expression is highly NF-jB-dependent in A549 cells No role for ERK and p38 MAPK docx

... Within resting cells, NF-jB is retained in the cytoplasm complexed to an inhibitor protein from the IjB family [3]. Stimulation with pro -in ammatory cytokines, such as tumour necrosis factor ... protein was rapidly induced (Fig. 1). This was first apparent by 2 h poststim- ulation and levels of ICAM-1 protein continued to rise over the 18 h of the experiment. To exam...
Ngày tải lên : 07/03/2014, 15:20
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Báo cáo khoa học: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers Implications for the epilepsy seen in the dementia FENIB ppt

Báo cáo khoa học: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers Implications for the epilepsy seen in the dementia FENIB ppt

... inclusions of neuroserpin within c ortical a nd subcortical neurons [1–3]. Neuroserpin is a member of the serine proteinase inhibitor or serpin s uperfamily. It inhibits the enzyme tissue plasminogen ... Neuroserpin polymers result from the sequential insertion of t he reactive centre loop of one molecule into b-sheet A of another [1,6]. The resulting s pecies is inactiv...
Ngày tải lên : 07/03/2014, 16:20
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Báo cáo khoa học: Androgen receptor function is modulated by the tissue-specific AR45 variant ppt

Báo cáo khoa học: Androgen receptor function is modulated by the tissue-specific AR45 variant ppt

... leads to glucocorticoid resistance in a number of pathological conditions [24]. In the case of the mineralocorticoid receptor a variant lacking the hinge and ligand-binding regions but able to increase ... [14]. They are organized in a modular fashion and act by binding to DNA response elements found in the regulatory regions of their target genes [14]. Due to...
Ngày tải lên : 07/03/2014, 16:20
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Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot

Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot

... has been shown to form a complex with the adaptor pro- tein Fe65 and the histone acetyltransferase Tip60 that is capable of inducing transcription of reporter genes [44]. The ability to form transcriptionally ... cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins. Biochem- ist...
Ngày tải lên : 15/03/2014, 10:20
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