Báo cáo khoa học: MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-jB1 ppt

... 0.05).MiR-9 inhibits ovarian cancer cell growth L M. Guo et al.5540 FEBS Journal 276 (2009) 5537–5546 ª 2009 The Authors Journal compilation ª 2009 FEBSKnockdown of NF-jB1 inhibits ES-2 cells growth in ... relative NF-jB1 expression level (mean ± SD) is shown (*P < 0.05).Fig. 6. Knockdown of NF-jB1 inhibits growth of ES-2 cells in vitro.(A) The validity of pSilencer ⁄ si -NF-jB1 (si -NF-jB1) ... 5537–5546 ª 2009 The Authors Journal compilation ª 2009 FEBS MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-jB1 Li-Min Guo*, Yong Pu*, Zhe Han*, Tao Liu, Yi-Xuan Li, Min Liu,...

Báo cáo khoa học: Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism pptx

... death.Table 1. Percentage of cells in each phase of the cell cycle asevaluated by ﬂow cytometry.Percentage of cells in the phases of thecellcycleG1SG2⁄ M Cell deathC33A Control 40 21 ... risk of development of cancer. Oral administration of DHEA to mice inhibits spontaneous breast cancer andchemically induced tumors of the lung and colon [7];however, its effect in cervical cancer ... antiproliferative effect of DHEA has been asso-ciated with an arrest of the cell cycle and cell death inBV-2 cells, a murine microglial cell line, in hepatoma cell lines and in HepG2 cells [25,54,55]....

Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

... Central administration of oleic acid inhibits glucose production and food intake. Diabetes51, 271–275.16 Woods SC, Seeley RJ & Cota D (2008) Regulation of food intake through hypothalamic ... entry of fatty acid into mitochon-dria. Thus, the steady-state level of malonyl-CoA inthese tissues is determined by the relative activities of ACC and malonyl-CoA decarboxylase.Role of the ... aspects of the affects of fructose on foodintake, these ﬁndings lend further support to the mech-anism by which malonyl-CoA participates in the regu-lation of feeding behavior.Role of carnitine...

Báo cáo khoa học: Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through both extracellular signal-regulated kinase and phosphatidylinositol 3-kinase⁄Akt pathways pot

... the growth of both mesenchymal chondroprogeni-tor cells and chondrosarcoma-derived chondrocytic cells in vitro. However,the cartducin-signaling pathways responsible for the regulation of cell ... pro-liferation of these cells.Another signaling pathway associated with the con-trol of cell proliferation is the PI3K ⁄ Akt pathway. It isalso an important mediator of cell growth and survivalin ... involvement of thePI3K ⁄ Akt pathway in the ability of cartducin to sti-mulate proliferation of these cells.DiscussionSkeletal development requires the condensation of multipotential mesenchymal cells...

Báo cáo khoa học: "A New Approach to the Mechanical Syntactic Analysis of Russian" ppt

... vast capacity of the human brain by the paltry contents of an electronic contraption, the absurdity of * This work was sponsored by the Office of Ordnance Research, Department of the Army. ... insertion of a signal into the profile skeleton (PS). PART II Part II of the projected scheme, now in process of be- ing programmed, has the purpose of analyzing the syntactical structure of each ... is placed in the normal position of the target T for final printout. ILLUSTRATION 1. As an example of the performance of this section of the program, we offer the text word РАСПОЛОЖЕНИЕ....

Báo cáo khoa học: "UNDERSTANDING REPETITION IN NATURAL LANGUAGE INSTRUCTIONS - THE SEMANTICS OF EXTENT" pptx

... discuss the issue of extent in more detail s . Karlin [3], presents a semantic analysis of verbal modifiers in the domain of cooking tasks. Much of this is pertinent to an examination of extent, ... required, and some of these are discussed in the rest of this paper. Semantics of verbal modifiers In analysing the semantics of verbal modifiers, Karlin[3] identifies three kinds of modifiers, ... theme of my thesis is that both scope and extent must be accounted for in a full treatment of repetition, but a discussion of scope is outwith the scope of this paper. 279 1 The number of repetitions...

Báo cáo khoa học: Sp1 and Sp3 are involved in up-regulation of human deoxyribonuclease II transcription during differentiation of HL-60 cells pptx

... involved in up -regulation of humandeoxyribonuclease II transcription during differentiation of HL-60 cellsSan-Fang Chou1, Hui-Ling Chen2* and Shao-Chun Lu1*1Department of Biochemistry ... IImediates the digestion of internucleosomal DNA in apop-totic cells. Torriglia et al. [8] have shown that DNase II isinvolved in the degradation of ﬁber cell DNA during lens cell differentiation. ... inapoptotic cells after they are engulfed by phagocytic cells.Mice with targeted disruption of the DNase II gene die atbirth because of severe anemia [10] and/or asphyxiation [11];after examination of...

Tài liệu Báo cáo khoa học: Autophagy inhibits reactive oxygen species-mediated apoptosis via activating p38-nuclear factor-kappa B survival pathways in oridonin-treated murine ﬁbrosarcoma L929 cells doc

... SBSB020406080100************abcdefDCF positive cells (%)DCF positive cells (%)Percentage of sub-G1 cells (%)Percentage of sub-G1 cells (%)Fig. 6. Effects of NF-jB and p38 on oridonin-induced L929 cells apoptosis and ... and cell death [27]. The functionalroles of the activation of these kinases are often con-troversially discussed. The ERK1 ⁄ 2 cascade isregarded to be the main method of transmission for cell ... logarithmically growing cells.Measurement of intracellular ROS generationGeneration of intracellular ROS was examined by DCF-DA, which is a relatively speciﬁc probe for intracellularROS formation....

Tài liệu Báo cáo khoa học: Oxidation inhibits amyloid ﬁbril formation of transthyretin ppt

... calculated as the percentage of the turbidity (absorbance at 330 nm) of the oxidizedproteins divided by the turbidity of the unoxidizedproteins. Oxidation reduced ﬁbril growth of the WTprotein by ... of V30M TTR protein, oxidation reducedﬁbril growth by 90% after 1 day and 74% after14 days. After 1 day of incubation, 60% of the unoxi-dized V30M TTR was in the supernatant, whereas80% of ... 2006)doi:10.1111/j.1742-4658.2006.05532.xThe role of amino acid side chain oxidation in the formation of amyloidassemblies has been investigated. Chemical oxidation of amino acid sidechains has been used as a facile method of introducing...

Báo cáo khoa học: Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding Pallavi Srivastava and Dulal Panda ppt

... theHeLa cells on ice for 1 h. Then, the kinetics of thereassembly of the microtubules in live HeLa cells wasBAFig. 3. Effects of rotenone on the microtubules of MCF-7 and HeLa cells. Cells ... 1. Effect of rotenone on the proliferation of mammalian cells.(A) Rotenone inhibited the proliferation of HeLa (s), and MCF-7 (d)cells. Cell proliferation was determined after one cell cycle ... microtubules of both cell types. However,it had a much stronger effect on the interphase microtubules of MCF-7cells compared to that of the HeLa cells. Rotenone suppressed the reassem-bly of microtubules...

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