... decarboxylation catalysed by a- amino-b-carboxymuconate-e-semialdehyde decarbox-ylase. J Am Chem Soc 129, 9278–9279.20 Fukuoka SI, Ishiguro K, Yanagihara K, Tanabe A, Egashira Y, Sanada H & ... picolinicacid (PA), quinolinic acid (QA) and NAD homeostasis. Indeed, the enzymestands at a branch point of the tryptophan to NAD pathway, and deter-mines the final fate of the amino acid, i.e. transformation ... potential medical interest, and suggest a regulatory link between de novo NAD biosynthesis and glycolysis.AbbreviationsACMS, a- amino-b-carboxymuconate-e-semialdehyde; ACMSD, a- amino-b-carboxymuconate-e-semialdehyde...