... orSTIM2, acting as a Ca2+sensor, located in the ERmembrane, are translocated to the plasma membraneand clustered at the ER-plasma membrane junctionsafter the detection of a shortage of Ca2+in ... inositol-1,4,5-trisphosphate; Jak2, Janus kinase 2; JM, juxtamembrane; LD, like domain; NCX, Na+⁄ Ca2+exchanger; NLS,nuclear localization sequence; PKC, protein kinase C; PMCA, plasma membrane Ca2+-ATPase; ... could form an antiparallel heli-cal dimer, and that the side chains of the basic aminoacids could interact with the negatively-charged innerleaflet of the plasma membrane [69].Kinetics measurements,...