... 1C).Increased nucleolin/C23 protein levels in Hsp70-transfected cells in response toH2O2-induced apoptosisWe next examined the expression of nucleolin ⁄ C23protein in these cells in response ... complexes with other factors,such as casein kinase II, c-Myb, midkine, histone H1,nucleophosmin, p53 and protein phosphatase 1. Anumber of studies, including our own, indicate thatnucleolin ⁄ C23 ... mmolÆL)1H2O2for 12 h and harvested for the determination of protease activity of caspase-3 using the caspase colorimetric assaykit. Data were obtained from four independent experiments.*P < 0.05...