Báo cáo khoa học: Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis docx
Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc
... in actin filament assemblyin the actin patch. Binding of the LBD to Las17p mayalso stimulate Las17p-dependent activation of the Arp2 ⁄ 3 complex. De novo actin filament assembly iscritical for ... importance of WASP–WIP interaction in mammalian cells is sup-ported by the observation that the vast majority of the disease-causing missense mutations in human WASPmap to the N-terminal WH1 ... actin-binding domainThirumaran Thanabalu1,2, Rajamuthiah Rajmohan2, Lei Meng2, Gang Ren4,5, Parimala R. Vajjhala4and Alan L. Munn1,3,4,6*1 Institute of Molecular and Cell Biology, A* STAR Biomedical...
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Tài liệu Báo cáo khoa học: Deciphering enzymes Genetic selection as a probe of structure and mechanism docx
... which the genes encoding the bifunctional enzymes chorismate mutase–prephenate dehydratase and chorismate mutase–prephenate dehydratase were deleted. Monofunctionalversions of the dehydratase and ... better anticipate the naturalevolution of bacterial antibiotic resistance. Hydrolysis of aztreonam requires a change in the substrate specificity of TEM-1 b-lactamase. The chance of finding the threemutations ... [38]. A transition state analog, shownin a ball-and-stick representation, is bound in each of the active sites,which are located at the trimer interfaces. The location of the cystal-lographically...
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Tài liệu Báo cáo khoa học: "Using an Annotated Corpus as a Stochastic Grammar" ppt
... probabilities to these rules such that the probability of the parse of a equals 1/3, and the probability of the parse of ab equals 4/9. The parse of a can exhaustively be generated by applying ... We can estimate a probability as accurately as we want by choosing Nas large as we want, since according to the Strong Law of Large Numbers the estimated probability converges to the actual ... (ATIS) spoken language corpus. Preliminary experiments yield 96% test set parsing accuracy. 1 Motivation As soon as a formal grammar characterizes a non- trivial part of a natural language,...
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Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc
... local Src activation triggered the long-range propa-gation of active Src wave into the distal cell areas awayfrom the site of mechanical stimulation [50]. The mecha-nism of this wave propagation ... structure of the Abl/Argand Tec kinase families (in particular, of the c-Ablkinase) resembles the SFK structures. The c-Abl kinasepossesses three domains (SH2, SH3 and the two-lobekinase domain), ... Cellular Systems ModellingDatabase and can be accessed at http://jjj.biochem.sun.ac.za/database/kaimachnikov/index.html free of charge.Calculation of the QSS curves and steady states The QSS...
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Tài liệu Báo cáo khoa học: Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11⁄hippostasin ppt
... raised against KLK11 was the same size as that of the translational product by isoform 2mRNA (Fig. 4B). The product by isoform 1 mRNAwas smaller than the isoform 2 product. The multiplebands may ... 5¢-GGACTCAAGAGAGGAACCTG-3¢; F1b, 5¢-CTGCCTTGCTCCACACCTG-3¢; F1c, 5¢-CTGCCGTCTCCGCCGCCACT-3¢; FU, 5¢-TCAAGCCCCGCTACATAGTT-3¢; and R3, 5¢-AGGAACCAAACACCAAGTGG-3¢(Fig. 2A) .Luciferase promoter assayHuman ... 5¢-TCATGCTGGTTGAGACTGGA-3¢ and 5¢-CCAGGTGTGGAGCAAGGCAG-3¢) and a 938 bp fragment of promoter 3 (primers, 5¢-CTCACAGCAGCCAGTAAGTG-3¢ and 5¢-ACTCACAGGCTCTGGGGCTG-3¢) were amplified using a Taq polymerase...
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Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx
... 4¢-phosphopantothenate is not commercially available,it was synthesized enzymatically in situ by addingpantothenate kinase, His-CoaA,D-pantothenate andATP to the His-CoaB assay mixtures [5]. Therefore,0.9 ... with4¢-phosphopantothenoyl-CMP.Copurification of the 4¢-phosphopantothenoyl-CMPintermediateTaking into account that residues Arg206, Asn210 andAla276 are crucial for the second-half reaction of the bacterial PPC synthetase activity, ... byKupke et al. in 2000 [6] and was later confirmed for the plant PPC decarboxylase AtHAL 3a (AtCoaC) by purifyingoxidatively decarboxylated pantothenoylcysteine as a reac-tion intermediate [11] and...
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Tài liệu Báo cáo khoa học: Cell surface heparan sulfate proteoglycans Target and partners of the basic ®broblast growth factor in rat Sertoli cells pptx
... CTCTTTGATGACAGAAGTGCCT-3¢Syndecan-4 5¢-85 GAGTCGATTCGAGAGACTGA-3¢ 3655¢-450 AAAAATGTTGCTGCCCTG-3¢Glypican-1 5¢-566 GAATGACTCGGAGCGTACACTG-3¢ 4885¢-1054 CCTTTGAGCACATTTCGGCAA-3¢P450 aromatase 5¢-1555GCTTCTCATCGCAGAGTATCCGG-3¢ ... 5¢-1555GCTTCTCATCGCAGAGTATCCGG-3¢ 2895¢-1821CAAGGGTAAATTCATTGGGCTTGG-3¢b-actin 5¢-2350 ACAGACTACCTCATGAAGAT-3¢ 6655¢-3222 AGCCATGCCAAATGTCTCAT-3¢Fig. 1. Dose-related eect of bFGF on FSH-stimulated ... interassay coef®cients of variation were lessthan 10%. The analysis o f the radioimmunoassay data wasperformed using the SECURIAprogram from the PackardInstrument Company (Meriden, CT, USA).DNA...
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Tài liệu Báo cáo khoa học: Aldehydes release zinc from proteins. A pathway from oxidative stress⁄lipid peroxidation to cellular functions of zinc pptx
... release, the E-amino groups of lysines in MT2 were carbamoylated with potassiumcyanate and the modified protein was assayed for zincrelease as described above. Acetaldehyde releasesalmost the ... to a final concentration of 10 mgÆmL)1, andsolid potassium cyanate was added to a final concentration of 1 m. The reaction mixture was incubated at 37 °C for24 h. Excess potassium cyanate was ... 80 °C and used immediately. Malonaldehydetetrabutylammonium salt was used as a source of ‘malondi-aldehyde’. Evaporation of acetaldehyde during measure-ments was minimized by sealing the cuvettes...
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Tài liệu Báo cáo khoa học: Diol dehydratase-reactivating factor is a reactivase – evidence for multiple turnovers and subunit swapping with diol dehydratase pdf
... and the reactivase eluted separately at theirrespective retention times. In contrast, a peak of the freereactivase decreased and a new peak appeared in the presence of ADP. The latter peak was ... the enzymeÆreactivase complex was formed in smallamounts from apoenzyme and the reactivase and not atall from the enzymeÆCN-Cbl complex and the reactivase(data not shown).Affinity of the reactivase ... min)1at 37 °C from the initial rate. The time course of the reactivation of glycerol-inacti-vated holoenzyme by the reactivase in the presence of ATP and Mg2+at a molar ratio of the reactivase...
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Tài liệu Báo cáo khoa học: Catabolite repression in Escherichia coli – a comparison of modelling approaches docx
... exclusion,whereas phosphorylated EIIA activates adenylatecyclase (CyaA) and leads to an increase in the intra-cellular cyclic AMP (cAMP) level [1].Mathematical models of cataboliterepression ... the concentration (mass of a compound based on a certain volume, or mass of a compound based on the entire biomass as usual in bio-engineering) is the focus of the model, as in the twocontributions ... idea of a modular representation of cellularprocesses is very popular [21]. One advantage of the method of modular modeling is that the granularity of the submodels can easily be adjusted to the...
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Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnchuyên đề điện xoay chiều theo dạngNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Chuong 2 nhận dạng rui roKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt nam