Báo cáo khoa học: Assembly and molecular mode of action of the Helicobacter pylori Cag type IV secretion apparatus doc

... conserved and unique components of the Cag- T4SS, together withpotential implications for the current understanding of its mode of action. The cagPAI and the Cag type IV secretion apparatus Gene ... FEBSMINIREVIEW Assembly and molecular mode of action of the Helicobacter pylori Cag type IV secretion apparatus Wolfgang FischerMax von Pettenkofer-Institut, Ludwig-Maximilians-Universita¨t, ... components, see the accom-panying review by Cendron and Zanotti [27]. The putative type IV secretion apparatus corecomplex The assembly of different type IV secretion machines and functions of their...

Báo cáo khoa học: Architecture of the Helicobacter pylori Cag-type IV secretion system pdf

... proteins in the T4SS apparatus is not clear,although several of them are essential for the secretion of CagA or the induction of interleukin-8 [23]. The NTPases battery of the Cag- T4SS The Cag- T4SS ... picture of the architecture and func-tion of the Cag- encoded T4SS can be derived.Architecture of T4SS The T4SS apparatus generally consists of twelve pro-teins named VirB1–11 and VirD4 based on the ... example, the human pathogen Helicobacter pylori encodes aT4SS, the Cag- T4SS, which mediates the injection of the toxin CagA. Wereview the progress made in the past decade in our understanding of...

Tài liệu Báo cáo khoa học: Isolation and molecular characterization of a novel D-hydantoinase from Jannaschia sp. CCS1 docx

... performed usingT-COFFEE [44].Docking simulation of substrate on the active site of HYDJs The substrate binding pockets of HYDJs and the mode of interaction between substrate and enzyme were ... A3(2).Cloning and expression of the putative hydgenes The deduced open reading frames of putative hydgenes were PCR-ampliﬁed from the genomic DNA of the corresponding organisms. The PCR fragments of the ... homology model of the structure of HYDJswasgenerated to further investigate the structural basis for the higher activity of HYDJscompared to HYDBp. The Z-score for the homology model HYDJsbased...

Tài liệu Báo cáo khoa học: Biochemical and molecular characterization of hazelnut (Corylus avellana) seed lipoxygenases pdf

... products of the hazelnutLOX were compared with the reaction products of soybeanLOX type I and authentic standards of 9- and 13-HODE.As shown in Fig. 4, 9-HODE is the main product of the hazelnut ... responsible for the LOXactivity in immature hazelnut seed.In order to correlate LOX activity and the production of C6 and C9aldehydes deriving from the activity of otherenzymes of the LOX pathway, ... produced by the activity of the divinyl ethersynthase [30,31] and may act as antifungal moleculesinhibiting the germination of the fungal spores [32].Moreover some other oxylipins deriving from...

Báo cáo khóa học: Biochemical and molecular characterization of a laccase from the edible straw mushroom, Volvariella volvacea docx

... also positively affected the activity and stability of the enzyme [40]. The effect of copper onenzyme stability may be related to the inhibitory effect of the metal on the activity of an extracellular ... T-vector and sequenced as above. The full-length cDNA of lac1 was then generated by 3¢-RACEusing the primer 5¢-TCTCAACCGTCGACAGCAGTGTTCGTG-3¢ designed from the sequence of the extreme5¢ end of ... 7).Although the spectral characteristics of the lac1 proteinsuggest the absence of a type 1 copper site, this is not borneout by analysis of the deduced amino acid sequence of the enzyme. Thus, the...

Báo cáo khoa học: NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist Structural implications for the MHC II (I-Au)–peptide complex from docking calculations ppt

... elucidate the role of the positively charged residue Arg78 and the effect of the reduction of cationicity of MBP in the triggering of multiplesclerosis. Flexible docking calculatio ns of the MBP(74–85)epitope ... eycharacteristic of the structure of the native epitope inMe2SO is the presence of a large number of electrostaticinteractions, especially in the central region of the peptide. The side chain of Arg78 ... distantfrom the side chain of Arg78. The side chain of Arg78 is lesswell deﬁned, as in the case of aqueous solution, because of the absence of interactions with the s ide chains of A sp81 (in the agonist...

Báo cáo khoa học: Cellular and molecular action of the mitogenic protein-deamidating toxin from Pasteurella multocida pptx

... is the detection of the modiﬁcation, whichinvolves the detection of a molecular mass change of 1 Da in a relatively large protein substrate (20–45 kDa).Another challenge is the development of ... understanding of the structural and biochemical basis of the effects of these toxins on vari-ous host signaling pathways have provided interesting and sometimes surprising insights into the molecular mechanisms ... in the G-protein tar-get, which results in the activation of intrinsic GTPase activity. Structural and biochemical data point to the uniqueness of PMT among these toxinsin its structure and action. ...

Báo cáo khoa học: Biochemical and molecular characterization of puriﬁed chicken pancreatic phospholipase A2 docx

... concentrations of Ca2+, usingPC as substrate, at pH 9.5 and at 37 °C in the presence of 1 mMNaTDC. The star indicates the phospholipase activity measured in the absence of CaCl2 and in the presence of ... of the hydrolysis products [12,19]. In order to investigate the effect of bile salts on ChPLA2activity, the rate of hydrolysis of PC by ChPLA2in the presence of vari-ous concentrations of ... a-carbons). The Ramachandran plot statistics of ChPLA2 and the complex ChPLA2–substrate analogmodel showed that 97% and 94.6–97.3% of the resi-dues were in the most favored or in the additionalallowed...

Tài liệu Báo cáo khoa học: Enzymatic and electron paramagnetic resonance studies of anabolic pyruvate synthesis by pyruvate: ferredoxin oxidoreductase from Hydrogenobacter thermophilus doc

... thermophilus and its close relatives [16,17]; in theseorganisms, the heteropentameric POR and OGORfunction as the key components of the reductive TCAcycle and catalyze the anabolic reductive carboxylation of ... intermediate in both the oxidative and reductive reactions. The HE-TPP radical wasformed only after the reduction of the iron-sulfur clus-ters of the enzyme, suggesting that the electrons sup-plied ... thatH. thermophilus POR functions toward pyruvate syn-thesis in vivo.To investigate the reaction mechanism of H. thermo-philus POR, we measured the EPR spectra of the enzyme in the presence of...

Tài liệu Báo cáo khoa học: Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus doc

... the numbering of the amino-acid sequences of immunoglobulins and the deﬁnition of their CDR loops, as described from 1997 [13]. The number-ing and deﬁnition of the L-CDR3 and H-CDR3 loops of mAb4E11 ... segment, and the VH-D, D-JH, and VL-JLjunctions [17]. They are located at the center of the antibody combining site [18,19] and provide the major part of the free energy of interaction with the ... 1).Kinetics of the interactionTo analyse the contributions of the residues in the CDR3 loops to the kinetics of interaction between the Fab4E11-H6 fragment and its MalE-E3-H6 antigen,we measured the...

Xem thêm

Từ khóa: báo cáo khoa học mẫu báo cáo khoa học y học báo cáo khoa học sinh học báo cáo khoa học nông nghiệp báo cáo khoa học lâm nghiệp báo cáo khoa học thủy sản Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018 Báo cáo quy trình mua hàng CT CP Công Nghệ NPV chuyên đề điện xoay chiều theo dạng Nghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấp Một số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTP Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Phát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninh Trả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ long Nghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùng Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tin Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khí Sở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIX Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)chuong 1 tong quan quan tri rui ro Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật