... Paparelli2, and F. Fornai2;31Department of Neuroscience, Section of Neurology,2Department of Human Morphology and Applied Biology, University of Pisa, and 3Laboratory of Neurobiology of Movement Disorders, ... mutant disease- causing proteinThe principal disease- causing proteins, beta-amyloid and tau for Alzheimer’s (Fassbenderet al., 2001; Mandelkow and Mandelkow,1998), alpha-synuclein and parkin ... appraisal of brain pathology staging related to presymptomatic and symptomatic cases of sporadic Parkinson’s disease G. M. Halliday1, K. Del Tredici2, and H. Braa k21Prince of Wales Medical...