... promoting an increase in proopiomelanocortin and cocaine and amphetamineregulated transcript. Taken together, these findingsprovide a compelling argument for the role for malo-nyl-CoA in regulating ... fluctuations in the levels of blood glucose [13], fattyacids [12,14,15] and certain amino acids [16].A linkage between fatty acid synthesis in the CNS and feeding behavior was uncovered with the findingthat ... areknown to reach the CNS to effect changes in feedingbehavior and energy expenditure. Thus, insulin, leptin and ghrelin, as well as other hormones ⁄ cytokines,interact with their cognate receptors...