... Company, Boston.[35] Lehtovirta M, Laakso MP, Soininen H, Helisalmi S, Mannermaa A, Helkala EL, Partanen K, Ryynanen M, Vainio P, Hartikainen P, et al.1995. Volumes of hippocampus, amygdala and ... visuospatial/cognitive and language factors did not change.Increased age was associated with lower scores, and higher education with higher scores on all factors at each interval. No APOE allele wasassociated ... increases ADrisk. APOE may be an active participant in-amyloidclearance [25,30,40]. APOE deficient mice expressing theAPP717mutation that causes an early-onset, autosomaldominant form of AD...