... exciting area of research forwards into the future. Indeed, obtaining accurate measurements of the concentrations, distributions and flux of all the mainplayers involved in protein folding in the ... tostudying ligand binding to human PDI in solution. The x-linker region, a 20 amino acid spacer between the b¢ and a¢ domains, is likely to play an importantrole in controlling binding of substrates ... in the human genome, and understanding their specific func-tions and interrelationships is of considerable impor-tance, given their value to industry and medicine.Protein folding in vitro and...