Effects of Electrical Current in Human Body

... and Machinery Equipment Field Evaluation Services EFFECTS OF ELECTRICAL CURRENT IN THE HUMAN BODY Current Reaction Below 1 Milliampere Generally not perceptible 1 Milliampere Faint Tingle ... electric plug into an electric outlet. ü Don’t use temporary wiring in place of permanent wiring. If the equipment that in installed within your jurisdiction is not NRTL-Listed, AHJ inspectors ... shock felt. Not painful but disturbing. Average individual can let go. Strong involuntary reactions can lead to other injuries. 6 to 25 Milliampere (women) Painful shocks. Loss of muscle control....

... concept of human rights. Human rights as an article of faithAccording to a standard definition, human rights are those rights one has byvirtue of being human. 1This definition suggests that human ... belong toevery human being in every human society: all human beings have them, equallyand in equal measure. Implied in one’s humanity, human rights are generallypresented as being inalienable ... ConventionGiventhatthecasesIdiscussinthebookaremerelyillustrative,thereisastrongelementoffortuityinthewaythefive‘criticallight’chaptersareassembled.Theimageofthekaleidoscopecomestomindinthatitpointstoaninfinitenumberofcombinationsofeithertheoreticalorempiricalelements,orboth.IneachchapteritisasifIhadcollectedpiecesofcaselaw,shakenthem,andobservedtheresultingcombination–ifnotexactlysymmetry–inthemirror(orlight )of aparticulartheory.Icouldhaverepeatedtheexerciseoverandoveragain,adinfinitum,eitherwiththesameorwithslightlydifferentmaterial(caselaw)ormirrors(critiques).30Eachtimetheresultwouldhavebeendifferentbut,Iwouldargue,nolesscompelling.Theimageofthekaleidoscopedrawsattentiontothewayoursensesconstructpatternswhichdonot‘really’existexceptthroughtheartificeofreflection(theory).ItcouldbesaidthatIofferakaleidoscopicreadingoftheConvention,i.e.onegeneratingarrangementswhichare,ifnotaestheticallypleasing,atleastdeceptivelyattractiveintheirsimplicityand(imposed)regularity.AfriendwhoreadChapter3wasnotdeceived.Sheremarked,disapprovingly,thatitwasasthough...

... calcium-independentphospholipase A2participates in ER stress-inducedINS-1 insulinoma cell apoptosis by promoting cera-mide generation via hydrolysis of sphingomyelins byneutral sphingomyelinase. ... datasuggesting that some of the genes involved in thegenetics of Lewy body disease, have in common thefact that they impinge on ceramide metabolism. Oneshortfall of the present theory is the lack of ... destinations.Cells from NPC subjects show a decrease in acidsphingomyelinase activity, leading to the accumulation of sphingomyelin [27]. Because one of the pathwaysfor ceramide recycling...

... two intermediateprocessing products of the invariant chain accumulate [8].This indicates that the amount of cysteine peptidase activity in the processing compartment for the invariant chain ... prein-cubation of the primary antibody with anexcess of recombinant cystatin F [5] a totalabsorption of the signal was apparent.Fig. 6. Double staining of cystatin F and ER.(A) Cystatin ... characterization and use of monoclonal antibodiesagainst the major extracellular human cysteine proteinaseinhibitors cystatin C and kininogen. Scand. J. Clin. LaboratoryInvest 48, 573–582.15....

... incubating 50 lg of protein in 30 lLof50mMpotassium phosphatebuffer, pH 7.0, containing 50 mMKCl, protease andesterase inhibitors, and [3H]AcCoA (0.2 lCi, 8.3 lM)at37 °C for 15 min. ... activities of OAT:OAE-L provides a significant insight into the regula-tion of this important modification in normal as well as in diseased tissue. Based on this information a reduction in orhalting of ... isshown in Table 1, the expression of oligo-O-acetylated sialicacid appeared to be completely eliminated. Similar findingshave been observed in studies utilizing a series of human colorectal carcinoma...

... quercetin and hesperetin significantly enhancedthe sensitivity towards thioguanine in MRP4-expressingcells, whereas quercetin, daidzein, naringenin andhesperetin did so in MRP5-expressing cells, ... doxorubicin, quercetin, silymarin, hesperetin, daidz-ein, resveratrol, naringenin, GSH and GST were allobtained from Sigma Chemicals (Poole, UK). Acetoxy-methyl esters of calcein (calcein-AM) and of ... activity. Effects of quercetin and silymarin onphotoaffinity labelling of MRP1 and MRP4with [32P] 8-azidoATP[aP]To determine whether silymarin and quercetin bind tonucleotide (ATP)-binding sites...

... cyste-ine protease, legumain, because of removal of thekey amino acid in the legumain-binding site of cysta-tin C [22]. The amino acid substitutions reside in opposing parts of the cystatin C ... curve.Papain and cathepsin B inhibitionThe cysteine protease inhibitory capacity in cell lysates wasdetermined by measuring the inhibition of papain as well ascathepsin B. To measure the capacity of ... biolo-gical specificity of cystatin C. Identification of leucine 9 in the N-terminal binding region as a selectivity-confer-ring residue in the inhibition of mammalian cysteinepeptidases. J Biol...

... FNIII29 of TNX in a study of C-terminalTNX domains [20]. The recombinant TNX domains in our previous study were produced in prokaryotic cells[20], therefore glycosylation may in uence binding of native ... antibody against FNIII29–30. This is in linewith the sequence obtained using MS ⁄ MS, which showsthe most N-terminal part of the sequence for the75 kDa TNX species starting in the C-terminal ... species of  200 kDa was detected using an antibody directedagainst FNIII3–5 of bovine TNX. This N-terminalTNX species was not recognized by an antibody direc-ted against FNIII12–15 of bovine...

... N-termini of RGS8 protein[19,20]. The N-terminal deletion of RGS8 resulted in aremarkable decrease in the inhibitory effects of RGS8on Gaq-coupled responses. The nine amino acids in theN-termini ... of Biological Science, Allergan, Inc., Irvine, CA, USAHeterotrimeric guanine nucleotide-binding proteins(G proteins) comprise a superfamily that is involved in the transmission of ligand binding ... RGS5s proteins. T, total protein; M, mem-brane protein; C, cytosolic protein. Arrows indicate a 26 kDa protein of RGS5 and a 13 kDa protein of RGS5s.Alternative mRNA splicing variant of RGS5 Y....

... 16sequences in cervical carcinoma cell lines. J Virol 1987, 61:962-971.36. Kohler PO, Bridson WE: Isolation of hormone-producing clonal lines of human choriocarcinoma. J Clin Endocrinol Metab ... Choriocarcinoma of women maintained in serial passage in hamster and rat. Proc Soc Exp Biol Med 1959, 102:77-81.40. Pattillo RA, Gey GO: The establishment of a cell line of human hormone-synthesizing ... [1]. Currently, fourclasses of proteinases are known as being capable of breaking down nearly all components of the extracellularmatrix: serine proteinases, aspartatic proteases, cysteinproteinases...