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Tài liệu Báo cáo khoa học: "The Incremental Generation of Passive Sentences" pot

Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "The Incremental Generation of Passive Sentences" pot

... sketches some basic features of the SYNPHONICS account of the computational modelling of incremental language production with the example of the generation of passive sentences. The SYNPHONICS ... Incremental Language Production of This paper sketches some basic features of the SYNPHONICS account of the computational modelling of incremental language production with the example of ... Syntax of the Passive Before we proceed to the application of our process model to the production of passive sentences, we will sketch the basic features of the present SYNPHONICS account of...
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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... Moreover, orientation of the CDE ⁄ CHR inthe general context of a promoter appears to be rele-vant because inversion of the site in the humanCdc25C promoter resulted in a deregulation of cellcycle-dependent ... determine a role of NF-Y in theircontrol, a number of such genes were implicated tobe regulated through CCAAT-boxes. Cotransfection of dominant-negative NF-YA demonstrated thatmost of the Tome-1 ... investigatingdownregulation of the cyclin B2 promoter is that afterdeletion or mutation of constitutively activating sites,such as the destruction of CCAAT-boxes, small levels of reporter activity...
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Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc

Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc

... indicate that poly-merization of Gag occurs mainly through the forma-tion of an intermediate layer of cup-shaped structures,each made of one hollow hexameric ring of CAdomains placed immediately ... of the precise residues and interac-tions involved in the NTD–CTD interface [46]. Most of these involve side chains from helix 8 of the CTDwhich pack against the N-terminal end of helix 4 of the ... N-terminal end of helix 4 of the NTD of a neighboring subunit in the hexamer.Additional contacts involve helix 11 of the CTD andthe C-terminal end of helix 7 of the NTD of the neigh-boring subunit....
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Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly ppt

Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly ppt

... ring of CAP-1 inserts; the urea and dimethyla-monium groups of CAP-1 also make contacts with theside chains and ⁄ or backbones of several residues in theprotein. Thus, most of the contacts of ... shifts of the whole dimer-ization helix of CTD [27] (otherwise, those chemicalshifts are too broad to be observed because of thepresence of interconverting conformers) [29]. The bind-ing site of ... mature capsid of human immunodeficiency virus, HIV-1, is formed bythe assembly of copies of a capsid protein (CA). The C-terminal domain of CA, CTD, is able to homodimerize and most of the dimerization...
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Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

... biological function of the pro-form of bone morphogenetic protein-2 (BMP-2), a member of the transforminggrowth factor b (TGFb) ⁄ BLP superfamily. The role of the 263 amino acids of the pro-peptide ... experi-ments demonstrate binding of proBMP-2 tothe ECD of BMPR-IA. Interaction of BMP-2(A) and proBMP-2 (B) with immobilized ECD of BMPR-IA. Interaction of BMP-2 (C) andproBMP-2 (D) with ... effect of BMP-2 and proBMP-2 on the phosphorylation status of p38 was tested, addition of BMP-2 resulted inmaximal phosphorylation of p38 after 60 min, whileproBMP2 showed no induction of p38...
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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

... structure of hACMSD in complex with DHAPmay used for the design of potent and highly selectiveenzyme inhibitors that may prove to be of potentialinterest to reduce life-threatening complications of cerebral ... struc-ture-based rational design of enzyme inhibitors withpotential medical interest.Results and DiscussionOverall quality of the modelThe three-dimensional structure of hACMSD in com-plex with ... ccp4 suite of programs [39] was used for scaling. Structure deter-mination for hACMSD was performed by means of the molecular replacement technique, using the coordi-nates of a monomer of PfACMSD...
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Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

... 100 lm of (GlcNAc)1–4was analysed at thestart, in the middle and at the end of each series of sam-ples. The resulting average values of the standards (display-ing standard deviations of < ... 4MU-(GlcNAc)2assubstrate; 50 lL of supernatant was mixed with 50 lLof50 mm citrate–phosphate buffer, pH 3.8, containing 50 lm of substrate and 0.1 mgÆmL)1 of bovine serum albumin,giving a final volume of 100 lL. ... Reaction mixtures contained 1 lm of LlChi18A and ⁄ or 3 lm of LlCBP33A, 0.1 mgÆmL)1 of puri-fied bovine serum albumin, 0.1 mgÆmL)1 of b-chitin powderor 0.5 mgÆmL)1 of a-chitin powder, in 50 mm...
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Tài liệu Báo cáo khoa học: The intracellular region of the Notch ligand Jagged-1 gains partial structure upon binding to synthetic membranes docx

Tài liệu Báo cáo khoa học: The intracellular region of the Notch ligand Jagged-1 gains partial structure upon binding to synthetic membranes docx

... presence of SDS, and of random coil values for aprotein of the same sequence.Fig. S2. In-cell NMR.1H-15N HSQC spectra of theE. coli slurry [(A), not induced; (B), induced and of the supernatant ... spectra of J1_ic(7.0 lm) in buffer alone and in the presence of SDS (3mm) at pH 7.4 and at pH 6.Fig. S8. CD of J1_ic. Far-UV CD spectra of J1_ic(7.0 lm) in buffer alone and in the presence of ... Effect of pH. Far-UV CD spectra of J1_tmic(7.5 lm) in the presence of DMPG phospholipidvesicles (1 mm) at pH 7.4, after acidification to pH 6,and after return to pH 7.4.Fig. S7. CD of J1_ic....
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Tài liệu Báo cáo khoa học: The conformational stability of the Streptomyces coelicolor histidine-phosphocarrier protein Characterization of cold denaturation and urea–protein interactions doc

Tài liệu Báo cáo khoa học: The conformational stability of the Streptomyces coelicolor histidine-phosphocarrier protein Characterization of cold denaturation and urea–protein interactions doc

... understanding of the physical interactions underlyingthe structure, folding and the function of a protein requiresa detailed description of its conformational stability interms of the free energy of ... and values of the thermodynamic parameters governing the heat- andcold-denaturation processes have been obtained. Cold-denaturation of the protein is the result of the combination of an unusually ... were performed in the presence of differentamounts of urea ranging from 0 to 3M(with maximumtemperatures of 363 K) and from 5 to 6M(with maximumtemperatures of 323 K). Sample exposure to...
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Tài liệu Báo cáo khoa học: The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site docx

Tài liệu Báo cáo khoa học: The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site docx

... recognition of p NPP by the pNPP site at t he rear su rface of the N -domainis due the formation of an hydrogen bond of the NO2-group of pNPP with the amino group of N398. The hydrophobicity of the ... Characterization of 2¢,3¢-O-(2,4,6-trinitrocyclo hexad ieneylid ine) adenosine 5¢-triphos-phate as a fluorescent probe of the ATP site of sodium andpotassium aden osine triphosphatse. Determination of nucleotidebinding ... p-nitrophenylphosphatase of H4-H5loop–GST fusion proteins of different lengths. Theincreaseoftheintensityoffluorescence by TNP-ATP binding was recorded using various H4-H5loop–GST fusion proteins of different...
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