Tài liệu Báo cáo khoa học: "PLAN REVISION IN PERSON-MACHINE DIALOGUE" docx

... (sentence 14). In the case of inconsistent values (sentence 20), a subplan is inserted for explaining why the value is inconsistent and asking the user to change something in order to correct ... dialogues, we distinguish between task level goals and plans (e.g., investing, traveling), and communicative level inten- tions and speech acts (e.g., explaining, re- questing information) [2,6,11]. ... Communicative-Plans models contain the effects an elementary communicative intention of the system in terms of the immediate expectations about the - 156- PLAN REVISION IN PERSON-MACHINE DIALOGUE Cldo...

Tài liệu Báo cáo khoa học: "Structure-Sharing in Lexical Representation" docx

... subjects of finite verbs have nominative case, so in the FINITE class frame we stipulate (CASE NOMINATIVE) for the subject. If we used the complete mode of inheritance in determining the case ... outputs is an instance; each rule copies idiosyncratic information from the input frame while avoiding copy- ing information which can still be inherited; each rule takes as input a single-word ... grammatical information appearing in the make entry below is a consequence of our maintaining the strong position that only information which is idiosyncratic should be included in a lexical...

Tài liệu Báo cáo khoa học: "Information Presentation in Spoken Dialogue Systems" potx

... of interest for any rational user. All dominantoptions represent some tradeoff, but depending onthe user’s interest, some of them are more interest-ing tradeoffs than others.Pruning dominated ... forcooperative response generation in information dialogues. In AAAI/IAAI 1999 pp. 148–155.M. Steedman 2000. Information structure and the syntax-phonology interface. In Linguistic Inquiry, 31(4): 649–689.A. ... group-averageclustering. The algorithm begins by assigningeach unique attribute value to its own bin, and suc-cessively merging adjacent bins whenever the dif-ference between the means of the bins falls...

Tài liệu Báo cáo khoa học: Transient DNA ⁄ RNA-protein interactions docx

... investing time and effort in preparing andanalyzing the full-length protein can be extremelyrewarding, as shown by the information obtained withthe tumor suppressor protein BRCA2 and its interac-tion ... structure facilitating protein bind-ing (indirect) and speciﬁc amino acid–base contacts(direct). A recent examination of proteinÆnucleic acidstructures has shown how minor groove narrowingenhances ... plays a driving role in transient pro-teinÆnucleic acid interactions, as well as in selectingand stabilizing the speciﬁc ones. Indeed, it may be themost important factor in the indirect readout...

Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx

... CIP1is involved in gefitinib-induced growthinhibition in HNSCC [58]. Another group of cell-cycleregulatory molecules – those of the INK4 family – hasalso been implicated in gefitinib-induced inhibition ... consists of p15INK4b,p16INK4a, p18INK4cand p19INK4d.AG1478, which, like gefitinib and erlotinib, acts as aspecific inhibitor of the EGFR tyrosine kinase, hasbeen shown to result in a dose-dependent ... EGFR-targeting tyrosine kinase inhibitors(TKIs) in patients with NSCLC is closely associatedwith EGFR mutations such as del746-750 and L858R in the kinase domain [9–11]. Lung cancer cellsharboring...

Tài liệu Báo cáo khoa học: How disorder inﬂuences order and vice versa – mutual effects in fusion proteins containing an intrinsically disordered and a globular protein docx

... (2005) The intrinsically disordered C-terminaldomain of the measles virus nucleoprotein interacts withthe C-terminal domain of the phosphoprotein via twodistinct sites and remains predominantly ... (2008) Mappingalpha-helical induced folding within the intrinsically dis-ordered C-terminal domain of the measles virus nucleo-protein by site-directed spin-labeling EPR spectroscopy.Proteins 73, ... predicting protein binding regions in disordered proteins. Bioinformatics 25, 2745–2746.41 Uversky VN (2002) Natively unfolded proteins: a pointwhere biology waits for physics. Protein Sci...

Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface pdf

... are linked to accessory proteins (e.g. zonulaoccludens proteins and cingulin), forging a connectionto the actin cytoskeletons of endothelial cells [8]. Occlu-din is an  65 kDa phosphoprotein ... Claudins are  22 kDaphosphoproteins that are thought to help maintainhigh transendothelial electrical resistance. Three typesof claudins (claudin1 ⁄ 3, claudin5 and claudin12) arefound in ... integrins. After docking to the vesselwall, leukocytes extend their processes toward interen-dothelial junctions to search for abluminal chemokinecues. Chemokine–chemokine receptor interactionsencourage...

Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: therapeutic aspects of vascular endothelial growth factor doc

... vascular leaksduring the clinical course of brain diseases or duringthe treatment of brain ischemia using pro-angiogenicmedicine.AcknowledgementsThis work was supported by Grant -in- Aid Special ... stress,resulting in an aggressive phenotype in terms of inva-sion and metastasis in vivo [35].Late in its clinical course, malignant glioma isknown to show extensive cell migration, and becomemore invasive ... all tumors in the CNS), but occurs in von Hippel–Lindau (VHL) patients. This tumor occursnot in the cerebrum, but in limited areas such as theretina, cerebellum, brainstem and spinal cord....

Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke docx

... for t-PA-induced intracranial bleeding in mousemodels of focal stroke [37]. In this model, co-treatmentwith the broad-spectrum MMP inhibitor GM6001effectively reduced intracranial bleeding. Morerecently, ... reinter-preted in the context of angiogenesis in the brain. Is itpossible that some of the acute neurovascular events in the brain after stroke represent an endogenous attemptby the brain ... forangiogenesis and recovery? In this minireview, we sur-vey a few key events in the neurovascular unit, includ-ing blood–brain barrier (BBB) perturbations, matrixproteases, coupling between neurogenesis...

Tài liệu Báo cáo khoa học: Catabolite repression in Escherichia coli – a comparison of modelling approaches docx

... B do-mains being part of the phosphorylation chain and theEIIC domain representing the membrane domain. Asall components of the PTS, depending on their phos-phorylation status, can interact ... transferred to the incoming glucose. Thedegrees of phosphorylation of the various PTS proteins representstarting points for a number of signal transduction pathways.A. Kremling et al. Modelling catabolite ... glu-cose was reduced from saturating to limiting concen-trations. As the model comprises metabolic processes,protein–protein and protein–DNA interactions as wellas protein synthesis, it is expected...

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