Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx
Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx
... the presence of the endocannabinoids, anandamide and 2-arachidonoylglycerol (2-AG), the cannabinoid CB1 and CB2receptors, and one of the enzymes mostlyresponsible for endocannabinoid hydrolysis, ... frommonocytes, and as monocytes were previously described toexpress the endocannabinoid system, we investigated the presence and regulation of endocannabinoids, cannabinoidreceptors and FAAH in immature ... N-terminal and the first trans-membrane domain of the protein of the human and ratCB2receptor. The specificity of the CB1 and CB2antibodieswas described in McIntosh et al. [41] and in Shire...
- 8
- 645
- 0
Tài liệu Báo cáo Y học: Characterization and regulation of yeast Ca2+-dependent phosphatidylethanolamine-phospholipase D activity docx
... results indicate that SPO14/PLD1 may beinvolved in regulating the expression of genes that are part of the INO1 regulon [13]. Therefore, we examined the effect of the presence of inositol and choline ... Characterization and regulation of yeast PtdEtn-PLD activity (Eur. J. Biochem. 269) 3823 in the presence of Ca2+we lysed the yeast cells in the presence of Ca2+(10 mM)orEGTA(1mM) and examinedPtdEtn-PLD ... activity in response tooxidative stress. Wild-type cells were grown to mid log-phase in SCmedium. The cells were then aliquoted and incubated in the absence or in the presence of H2O2at the indicated...
- 10
- 499
- 0
Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx
... 36% of the interaction of the full peptide with the binding cavity of SM3. The sizes of the surfaces were determined using distances between ligandatoms and protein atoms of less than 3 A˚. These ... struc-ture into the binding cavity of SM3 and the binding epitopeobtained from STD NMR is very good.Comparison with the X-ray and previous NMR structuresAs mentioned above, in the crystal cell the ... residue and/ or by the binding contribution fromtheGalNAcresidue.Docking the glycopeptide to the antibody the sugar ringhas little contact to the protein surface. Only the N-acetylmethyl group...
- 12
- 717
- 0
Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx
... coordination of the phosphorylation of UTP and hydrolysis of glutamine foroptimal efficiency in CTP synthesis rather than just acting toincrease the rate of glutamine hydrolysis itself.Keywords: ... activity, (B) CTPsynthesis in the absence of GTP and (C) CTP synthesis in the presence of GTP. (A) Glutamine hydrolysis in the absence of nucleotides takesplace on the enzyme without any large structural ... binding analog of ATP. CTP synthesisrequires the presence of both the nucleotide substrates ATP and UTP. When phosphorylation of UTP is hindered by the absence of ATP, only glutamine hydrolysis...
- 8
- 698
- 0
Tài liệu Báo cáo Y học: Expression and characterization of active site mutants of hevamine, a chitinase from the rubber tree Hevea brasiliensis docx
... between the se two classes.Role of Tyr183 in catalysis In previous crystallographic studies it was shown that the hydroxyl side chain of Tyr183 is within hydrogen bondingdistance of the N-acetyl ... residue resultingfrom the cloning procedure has apparently been cleaved offduring the maturation of the e nzyme.Enzyme activity studies The lysozyme activities of the various hevamine variants ... the recombinant hevamine did not bind to the column,probably because of the high amount of arginine present in the refolding buffer. Even after repeated, extensivedialysis the recombinant hevamine...
- 9
- 616
- 0
Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx
... the phenotype of cells [53]. Further-more, in human breast tumors and cell lines, miR-17-5p and miR-20a are induced in a manner that dependson cyclin D1 and repress the expression of cyclin ... sig-naling pathway.Some other miRNAs are also reported to be inducedby the MAPK signaling pathway. In the human B-cellline Ramos, miR-155 is induced by signaling by the B-cell receptor through the ... pathways byrepressing the expression of components of the signal-ing pathways and, in some cases, components of othersignaling pathways, thus forming a complex regulatorynetwork (Fig. 1). The mitogen-activated...
- 9
- 684
- 0
Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx
... behave differently from the rest of the promoters. Of these, amino acid residues 243 and 275 are involved in DNA binding and 244 and 246are in very close proximity to DNA binding. This indi-cates ... either does not use these residues forbinding or that they are not necessary for binding as the DNA binds sufficiently hard to the other DNA bindingresidues. For the WAF1 and MDM2 promoters, the ... unknown severity. In Table 9, the predictionaccuracy is shown using difference sizes of the safetymargin. By increasing the safety margin, we can gofrom 77% accuracy and an MCC value of 0.52 to88%...
- 14
- 561
- 0
Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"
... age of 8 years, the top of the frontal sinuses is at the level of the orbital roof, and by the age of 10 years, the sinuses extend into the vertical portion of the frontal bone. The final adult ... By the age of 4 years, the average cranial extent of the frontal sinus reaches half the height of the orbit and extends just above the top of the most-anterior ethmoid cells. By the age of ... craniotomy because of the proximity of the sinus to the orbit and the anterior skull base [5]. The frequency of bilateral absence of the frontal sinus has been reported in 3-4% to 10% of several...
- 5
- 577
- 0
Tài liệu Báo cáo Y học: Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA pdf
... [6,7]. The methylationpattern is created by de novo methylation and demethyla-tion of the DNA, and maintained during mitosis bymaintenance methylation [reviews 8,9]. De novo methyla-tion of DNA ... methyl groups are always introduced, oneslowly by Dnmt3a or by de novo methylation catalyzed byDnmt1 and the second one very fast. Therefore, this effectcan only double the rate of DNA methylation, ... maintenance methylation in these regions. On the other hand, Dnmt3a and Dnmt3b are not capable of efficient de novo methylation of DNA in the absence of Dnmt1. Whereas the maintenance methylation is...
- 4
- 526
- 0
Tài liệu Báo cáo Y học: DNA and RNA damage by Cu(II)-amikacin complex docx
... results of the strand-break assay of yeasttRNAPhe in the presence of Ami, Cu(II)-Ami and the Cu(II)-Ami-H2O2 system, performed by means of poly-acrylamide gel electrophoresis. Strikingly, in the ... to the linear formIII. In the Cu(II) + H2O2 system, the amount of form IIincreased during the duration of the experiment. Only for the complex in the presence of hydrogen peroxide a furtherdegradation ... Also other amino-glycosides, as kanamycin A, neomycin B and a syntheticneomycin-neomycin dimer have been shown to inducefragmentation of tRNAPheat Y3 7 and additionally atm7G46 in the variable...
- 10
- 503
- 1
Từ khóa: Báo cáo y học tài liệu báo cáo tài liệu báo cáo môn triếttài liệu báo cáo tài chínhtài liệu báo cáo nghiên cứu khoa họcNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXChuong 2 nhận dạng rui roQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ